“Assessment of dietary patterns, physical activity and obesity from a national survey: Rural-urban health disparities in older adults,” by Steven A. Cohen, Mary L. Greaney, and Natalie J. Sabik (PLoS ONE 13(12): e0208268. doi.org/10.1371/journal.pone.0208268, XML, HTML, and .pdf format, 15p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0208268
“The role of obesity in exceptionally slow US mortality improvement,” by Samuel H. Preston, Yana C. Vierboom and Andrew Stokes (Vol. 115, No. 5, January 30, 2018, p. 957-961).
“Examining the Multigenerational Effects of Obesity, Overweight and Stunting in a Latin American Middle Income Country: The Case of Colombia,” by Mary McEniry, Carmen Elisa Florez, Renata Pardo, Rafael Samper-Ternent, and Carlos Cano-Gutierrez (CDE Working Paper 2017-07, 2017, .pdf format, 45p.).
Abstract:
Examining multigenerational effects on health in Latin American populations from grandparents to subsequent generations is a fruitful area for research. Many Latin American populations have experienced rapid demographic and nutritional changes across generations with possible consequences for older adult health and subsequent generations. Understanding the multigenerational effects of obesity – an important health concern internationally – and early life nutritional status on child stunting merits further consideration. Using comprehensive data collected on households and individuals throughout Colombia (ENDS, ENSIN), we examine differences in child health according to whether grandparents are living/not living in the household and the degree to which obesity and height in older generations predicts child obesity, overweight and stunting in multigenerational households. We find that households with children living with grandparents have a higher prevalence of child obesity and lower prevalence of stunting; junk food consumption is similar across all types of households. In multigenerational households, we find strong intergenerational associations between grandmother-mother obesity and mother-female child obesity (overweight), and strong multigenerational associations between (1) grandfather obesity and female child obesity and overweight; (2) grandmother obesity and male child overweight; and (3) grandparent height and child stunting, mediated by mother height. We conclude that grandparent proximity, family resources, and relationship to household head play an important role in child obesity, overweight and stunting. In spite of grandparent proximity, mother being present in the household is important in terms of child health. Puzzling gender patterns for obesity/overweight raises the possibility of additional multigenerational factors affecting child health.
Note: The link below is to the table of contents for the current issue of JAMA (Vol. 318, No. 3, July 18, 2017). Check with your organization’s information center for availability.
jamanetwork.com/journals/jama/issue/318/3
A. “Association of Changing Hospital Readmission Rates With Mortality Rates After Hospital Discharge,” by Kumar Dharmarajan, Yongfei Wang, Zhenqiu Lin, Sharon-Lise T. Normand, Joseph S. Ross, Leora I. Horwitz, Nihar R. Desai, Lisa G. Suter, Elizabeth E. Drye, Susannah M. Bernheim, and Harlan M. Krumholz (p. 270-278).
B. “Associations of Weight Gain From Early to Middle Adulthood With Major Health Outcomes Later in Life,” by Yan Zheng, JoAnn E. Manson, Changzheng Yuan, Matthew H. Liang, Francine Grodstein, Meir J. Stampfer, Walter C. Willett, and Frank B. Hu (p. 255-269).
“The Impact of Obesity on Adult Mortality: Assessment of Estimates with Applications,” by Alberto Palloni and Hiram Beltrán-Sánchez (WR-1193, May 2017, .pdf format. 26p.). Note: Links to the abstract and the full text of the paper available at:
“Aerobic or Resistance Exercise, or Both, in Dieting Obese Older Adults,” by Dennis T. Villareal, Lina Aguirre, A. Burke Gurney, Debra L. Waters, David R. Sinacore, Elizabeth Colombo, Reina Armamento-Villareal, and Clifford Qualls (Vol. 376, No. 20, May 18, 2017, p. 1943-1955).
“Metabolically Healthy Obesity and the Risk of Cardiovascular Disease in the Elderly Population,” by Klodian Dhana, Chantal M. Koolhaas, Elisabeth F. C. van Rossum, M. Arfan Ikram, Albert Hofman, Maryam Kavousi, and Oscar H. Franco (PLoS ONE 11(4): e0154273. doi:10.1371/journal.pone.0154273, XML, HTML, and .pdf format, 12p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0154273
Population Bulletin (Vol. 70, No. 2, December 2015, .pdf format, 19p.). Note: The main article of this article is “Aging Baby Boomers to Face Caregiving, Obesity, Inequality Challenges,” by Mark Mather, Linda A. Jacobsen, and Kelvin M. Pollard.
www.prb.org/Publications/Reports/2015/unitedstates-population-bulletin.aspx
“Abdominal Obesity and Brain Atrophy in Type 2 Diabetes Mellitus,” by Rachel E. D. Climie, Chris Moran, Michele Callisaya, Leigh Blizzard, James E. Sharman, Alison Venn, Thanh G. Phan, Richard Beare, Josephine Forbes, Nicholas B. Blackburn, and Velandai Srikanth (PLoS ONE 10(11): e0142589. doi:10.1371/journal.pone.0142589, XML, HTML, and .pdf format, 11p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0142589
“Prospective Cohort Study of Central Adiposity and Risk of Death in Middle Aged and Elderly Chinese,” by Shaneda Warren Andersen, Xiao-Ou Shu, Yu-Tang Gao, Xianglan Zhang, Hui Cai, Gong Yang, Hong-Lan Li, Yong-Bing Xiang, and Wei Zheng (PLoS ONE 10(9): e0138429. doi:10.1371/journal.pone.0138429, XML, HTML, and .pdf format, 13p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0138429
“Obesity and Hepatic Steatosis Are Associated with Elevated Serum Amyloid Beta in Metabolically Stressed APPswe/PS1dE9 Mice,” by Feng-Shiun Shie, Young-Ji Shiao, Chih-Wen Yeh, Chien-Hung Lin, Tsai-Teng Tzeng, Hao-Chieh Hsu, Fong-Lee Huang, Huey-Jen Tsay, and Hui-Kang Liu (PLoS ONE 10(8): e0134531. doi:10.1371/journal.pone.0134531, XML, HTML, and .pdf format, p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0134531
“SES Disparities in Obesity, Diabetes, and Hypertension among Older Adults in Low and Middle Income Countries,” by Mary McEniry and Zhangjun Zhou (PSC Research Report No. 15-841, July 2015, .pdf format, 27p.). Note: Links to the abstract and the full text of the paper available at:
“Adipocyte Secreted Factors Enhance Aggressiveness of Prostate Carcinoma Cells,” by Angela Moreira, Sofia S. Pereira, Madalena Costa, Tiago Morais, Ana Pinto, Rúben Fernandes, and Mariana P. Monteiro (PLoS ONE 10(4): e0123217. doi:10.1371/journal.pone.0123217, XML, HTML, and .pdf format, 16p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0123217
A. “Obesity accelerates epigenetic aging of human liver,” by Steve Horvath, Wiebke Erhart, Mario Brosch, Ole Ammerpohl, Witigo von Schönfels, Markus Ahrens, Nils Heits, Jordana T. Bell, Pei-Chien Tsai, Tim D. Spector, Panos Deloukas, Reiner Siebert, Bence Sipos, Thomas Becker, Christoph Rocken, Clemens Schafmayer, and Jochen Hampe (Vol. 111, No. 43, October 28, 2014, p. 15538-15543). Note: PNAS is providing open access to the full-text of this article.
www.pnas.org/content/111/43/15538.abstract
B. “LIMP-2 expression is critical for {beta}-glucocerebrosidase activity and {alphpa}-synuclein clearance,” by Michelle Rothaug, Friederike Zunke, Joseph R. Mazzulli, Michaela Schweizer, Hermann Altmeppen, Renate Lullmann-Rauch, Wouter W. Kallemeijn, Paulo Gaspar, Johannes M. Aerts, Markus Glatzel, Paul Saftig, Dimitri Krainc, Michael Schwake, and Judith Blanz (Vol. 111, No. 43, October 28, 2014, p. 15573-15578).
A. “Tissue injury and hypoxia promote malignant progression of prostate cancer by inducing CXCL13 expression in tumor myofibroblasts,” by Massimo Ammirante, Shabnam Shalapour, Youngjin Kang, Christina A. M. Jamieson, and Michael Karin (Vol. 111, No. 41, October 14, 2014, p. 14776-14781).
www.pnas.org/content/111/41/14776.abstract
B. “Modulation of age-related insulin sensitivity by VEGF-dependent vascular plasticity in adipose tissues,” by Jennifer Honek, Takahiro Seki, Hideki Iwamoto, Carina Fischer, Jingrong Li, Sharon Lim, Nilesh J. Samani, Jingwu Zang, and Yihai Cao (Vol. 111, No. 41, October 14, 2014, p. 14906-14911).
www.pnas.org/content/111/41/14906.abstract
C. “Vitamin D prevents cognitive decline and enhances hippocampal synaptic function in aging rats,” by Caitlin S. Latimer, Lawrence D. Brewer, James L. Searcy, Kuey-Chu Chen, Jelena Popovic, Susan D. Kraner, Olivier Thibault, Eric M. Blalock, Philip W. Landfield, and Nada M. Porter (Vol. 111, No. 41, October 14, 2014, p. E4359–E4366). Note: PNAS is providing open access to the full-text of this article.
www.pnas.org/content/111/41/E4359.abstract
D. “Proteopathic tau seeding predicts tauopathy in vivo,” by Brandon B. Holmes, Jennifer L. Furman, Thomas E. Mahan, Tritia R. Yamasaki, Hilda Mirbaha, William C. Eades, Larisa Belaygorod, Nigel J. Cairns, David M. Holtzman, and Marc I. Diamond (Vol. 111, No. 41, October 14, 2014, p. E4376–E4385).
“Obesity in an Ageing Society: Implications for health, physical function and health service utilisation,” by iobhan Leahy, Anne Nolan, Jean O’ Connell, Rose Anne Kenny (July 2014, .pdf format, 73p.).
tilda.tcd.ie/assets/pdf/Obesity_in_an_Ageing_Society_Report.pdf
“Validation of a Pre-Coded Food Diary Used among 60–80 Year Old Men: Comparison of Self-Reported Energy Intake with Objectively Recorded Energy Expenditure,” by Tonje H. Stea, Lene F. Andersen, Goran Paulsen, Ken J. Hetlelid, Hilde Lohne-Seiler, Svanhild Adnanes, Thomas Bjornsen, Svein Salvesen, and Sveinung Berntsen (PLoS ONE 9(7): e102029. doi:10.1371/journal.pone.0102029, XML, HTML, and .pdf format, 6p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0102029
“The Relationship between Obesity and Diabetes among Mexican Elderly: Results from MHAS 2001-2014,” by Guido Pinto (Working Paper No. 2014-04, 2014, .pdf format, 21p.).
Abstract:
Objective. To assess the magnitude of the relationship between obesity and type 2 Diabetes Mellitus (T2DM) among Mexican elderly population. Material and
Methods. Data from the 2001, 2003, and 2012 Mexican Health and Aging Study (MHAS) was used and estimates were obtained using multivariate logit regression methods for panel data.
Results. Logit models produced positive, strong, and significant estimates of the relationship between obesity and T2DM at the population-level, after adjusting for respondent’s individual traits and thus, show that obese individuals, particularly those with abdominal obesity, are more likely to develop diabetes.
Conclusion. The empirical findings gleaned in this paper provide additional evidence of the role of obesity as the primary driver of diabetes. This means that reductions in obesity rates, especially waist obesity, may lead to important declines in morbidity and mortality from diabetes, which consequently may lead to cost reductions for the health system.
“Extended lifespan and reduced adiposity in mice lacking the FAT10 gene,” by Allon Canaan, Jason DeFuria, Eddie Perelman, Vincent Schultz, Montrell Seay, David Tuck, Richard A. Flavell, Michael P. Snyder, Martin S. Obin, and Sherman M. Weissman (Vol. 111, No. 14, April 8, 2014, p. 5313-5318)
“How Will More Obesity and Less Smoking Affect Life Expectancy?” by Samuel H. Preston, Andrew Stokes, Neil K. Mehta and Bochen Cao (IB No. 14-2, January 2014, .pdf format, 7p.).
crr.bc.edu/briefs/how-will-more-obesity-and-less-smoking-affect-life-expectancy/
“AMPK and Insulin Action – Responses to Ageing and High Fat Diet,” by Christian Frosig, Thomas E. Jensen, Jacob Jeppesen, Christian Pehmoller, Jonas T. Treebak, Stine J. Maarbjerg, Jonas M. Kristensen, Lykke Sylow, Thomas J. Alsted, Peter Schjerling, Bente Kiens, Jorgen F. P. Wojtaszewski, and Erik A. Richter (PLoS ONE 8(5): e62338. doi:10.1371/journal.pone.0062338, XML, HTML, and .pdf format, p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062338
A. “Fingolimod Phosphate Attenuates Oligomeric Amyloid {beta}-Induced Neurotoxicity via Increased Brain-Derived Neurotrophic Factor Expression in Neurons,” by Yukiko Doi, Hideyuki Takeuchi, Hiroshi Horiuchi, Taketo Hanyu, Jun Kawanokuchi, Shijie Jin, Bijay Parajuli, Yoshifumi Sonobe, Tetsuya Mizuno, and Akio Suzumura (PLoS ONE 8(4): e61988. doi:10.1371/journal.pone.0061988, XML, HTML, and .pdf format, 10p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0061988
B. “Dietary Iron Concentration May Influence Aging Process by Altering Oxidative Stress in Tissues of Adult Rats,” by Lorena Fernandes Arruda, Sandra Fernandes Arruda, Natalia Aboudib Campos, Fernando Fortes de Valencia, and Egle Machado de Almeida Siqueira (PLoS ONE 8(4): e61058. doi:10.1371/journal.pone.0061058, XML, HTML, and .pdf format, 12p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0061058
C. “Amyloid-{beta} Peptide on Sialyl-Lewis{X}-Selectin-Mediated Membrane Tether Mechanics at the Cerebral Endothelial Cell Surface,” by Sholpan Askarova, Zhe Sun, Grace Y. Sun, Gerald A. Meininger, and James C-M. Lee (PLoS ONE 8(4): e60972. doi:10.1371/journal.pone.0060972, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0060972
D. “Mitotic Spindle Defects and Chromosome Mis-Segregation Induced by LDL/Cholesterol-Implications for Niemann-Pick C1, Alzheimer’s Disease, and Atherosclerosis,” by Antoneta Granic and Huntington Potter (PLoS ONE 8(4): e60718. doi:10.1371/journal.pone.0060718, XML, HTML, and .pdf format, p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0060718
E. “Obesity and Risk of Hip Fracture in Adults: A Meta-Analysis of Prospective Cohort Studies,” by Xianye Tang, Gang Liu, Jian Kang, Yang Hou, Fungui Jiang, Wen Yuan, and Jiangang Shi (PLoS ONE 8(4): e55077. doi:10.1371/journal.pone.0055077, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0055077
“Physical Inactivity Mediates the Association between the Perceived Exercising Behavior of Social Network Members and Obesity: A Cross-Sectional Study,” by Janette S. Leroux, Spencer Moore, Lucie Richard, and Lise Gauvin (PLoS ONE 7(10): e46558. doi:10.1371/journal.pone.0046558, XML, HTML, and .pdf format, 6p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0046558
“Prevalence of Obesity Among Older Adults in the United States, 2007-2010,” by Tala H.I. Fakhouri, Cynthia L. Ogden, Margaret D. Carroll, Brian K. Kit, and Katherine M. Flegal (Data Brief No. 106, September 2012, .pdf format, 8p.).
A. “Waist-to-Height Ratio and Cardiovascular Risk Factors in Elderly Individuals at High Cardiovascular Risk,” by Marta Guasch-Ferre, Monica Bullo, Miguel Angel Martínez-Gonzalez, Dolores Corella, Ramon Estruch, María-Isabel Covas, Fernando Aros, Julia Warnberg, Miquel Fiol, Jose Lapetra, Miguel Angel Munoz, Lluís Serra-Majem, Xavier Pinto, Nancy Babio, Andres Díaz-Lopez, and Jordi Salas-Salvado (PLoS ONE 7(8): e43275. doi:10.1371/journal.pone.0043275, XML, HTML, and .pdf format, 6p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0043275
B. “A Synthetic Peptide with the Putative Iron Binding Motif of Amyloid Precursor Protein (APP) Does Not Catalytically Oxidize Iron,” by Kourosh Honarmand Ebrahimi, Peter-Leon Hagedoorn, and Wilfred R. Hagen (PLoS ONE 7(8): e40287. doi:10.1371/journal.pone.0040287, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0040287
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