“Identification of fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration,” by Meenakshi Ambati, Ivana Apicella, Shao-bin Wang, Siddharth Narendran, Hannah Leung, Felipe Pereira, Yosuke Nagasaka, Peirong Huang, Akhil Varshney, Kirstie L. Baker, Kenneth M. Marion, Mehrdad Shadmehr, Cliff I. Stains, Brian C. Werner, Srinivas R. Sadda, Ethan W. Taylor, S. Scott Sutton, Joseph Magagnoli, and Bradley D. Gelfand (Vol. 118, No. 41, October 12, 2021, e2102975118).
October 12, 2021
CAAR – Proceedings of the National Academy of Sciences Article Abstract – October 12, 2021
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May 20, 2021
CAAR – Public Library of Science (PLoS) Articles – May 20, 2021
A. “The impact of urinary incontinence on falls: A systematic review and meta-analysis,” by Shinje Moon, Hye Soo Chung, Yoon Jung Kim, Sung Jin Kim, Ohseong Kwon, Young Goo Lee, Jae Myung Yu, and Sung Tae Cho ( PLoS ONE 16(5): e0251711. doi.org/10.1371/journal.pone.0251711, XML, HTML, and .pdf format, 18p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0251711
B. “The impact of glucosamine on age-related macular degeneration in patients: A nationwide, population-based cohort study,” by Kathy Ming Feng, Wu-Chien Chien, Jiann-Torng Chen, Yi-Hao Chen, Chi-Hsiang Chung, Chien-An Sun, and Ching-Long Chen (PLoS ONE 16(5): e0251925. doi.org/10.1371/journal.pone.0251925, HTML, XML, and .pdf format, 15p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0251925
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June 10, 2020
CAAR – Proceedings of the National Academy of Sciences Article – June 10, 2020
Note: Check with your organization’s library for availability. “Altered photoreceptor metabolism in mouse causes late stage age-related macular degeneration-like pathologies,” by Shun-Yun Cheng, Joris Cipi, Shan Ma, Brian P. Hafler, Rahul N. Kanadia, Richard S. Brush, Martin-Paul Agbaga, and Claudio Punzo (Vol. 117, No. 23, June 9, 2020, p. 13094-13104). Note: _PNAS_ is providing open access to the full-text of this article.
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April 20, 2020
CAAR – Public Library of Science (PLoS) Articles – April 20, 2020
A. “Detecting vision loss in intermediate age-related macular degeneration: A comparison of visual function tests,” by Susanne G. Pondorfer, Manuel Heinemann, Maximilian W. M. Wintergerst, Maximilian Pfau, Annika L. Strömer, Frank G. Holz, and Robert P. Finger (PLoS ONE 15(4): e0231748. doi.org/10.1371/journal.pone.0231748, HTML, XML, and .pdf format, 12p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0231748
B. “Urine dicarboxylic acids change in pre-symptomatic Alzheimer’s disease and reflect loss of energy capacity and hippocampal volume,” by K. J. Castor, S. Shenoi, S. P. Edminster, T. Tran, K. S. King, H. Chui, J. M. Pogoda, A. N. Fonteh, and M. G. Harrington (PLoS ONE 15(4): e0231765. doi.org/10.1371/journal.pone.0231765, XML, HTML, and .pdf format, 18p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0231765
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January 29, 2020
CAAR – Public Library of Science (PLoS) Article – January 29, 2020
“Age- and sex-based evaluation of the association between refractive error and age-related macular degeneration in the Korean population,” by Kook Lee, Jin-Woo Kwon, Wan Jin Jahng, Young-Hoon Park, and Donghyun Jee (PLoS ONE 15(1): e0228468. doi.org/10.1371/journal.pone.0228468, XML, HTML, and .pdf format, 13p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0228468
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November 26, 2019
CAAR – Proceedings of the National Academy of Sciences Article Abstract – November 26, 2019
Note: For full text availability check your organization’s library.
A. “Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration,” by Andrew P. Voigt, Kelly Mulfaul, Nathaniel K. Mullin, Miles J. Flamme-Wiese, Joseph C. Giacalone, Edwin M. Stone, Budd A. Tucker, Todd E. Scheetz, and Robert F. Mullins (Vol. 116, No. 48, November 26, 2019, p. 24100-24107).
www.pnas.org/content/116/48/24100
B. “Elovanoids counteract oligomeric {beta}-amyloid-induced gene expression and protect photoreceptors,” by Khanh V. Do, Marie-Audrey I. Kautzmann, Bokkyoo Jun, William C. Gordon, Robert Nshimiyimana, Rong Yang, Nicos A. Petasis, and Nicolas G. Bazan (Vol. 116, No. 48, November 26, 2019, p. 24317-24325).
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November 19, 2019
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – November 19, 2019
Note: Check with you organization’s library for availability.
A. “N,N′-Diacetyl-p-phenylenediamine restores microglial phagocytosis and improves cognitive defects in Alzheimer’s disease transgenic mice,” by Min Hee Park, Misun Lee, Geewoo Nam, Mingeun Kim, Juhye Kang, Byung Jo Choi, Min Seock Jeong, Kang Ho Park, Wan Hui Han, Eunyoung Tak, Min Sun Kim, Juri Lee, Yuxi Lin, Young-Ho Lee, Im-Sook Song, Min-Koo Choi, Joo-Yong Lee, Hee Kyung Jin, Jae-sung Bae, and Mi Hee Lim (Vol. 116, No. 47, November 19, 2019, p. 23426-23436).
www.pnas.org/content/116/47/23426
B. “Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina,” by Shoji Notomi, Kenji Ishihara, Nikolaos E. Efstathiou, Jong-Jer Lee, Toshio Hisatomi, Takashi Tachibana, Eleni K. Konstantinou, Takashi Ueta, Yusuke Murakami, Daniel E. Maidana, Yasuhiro Ikeda, Shinji Kume, Hiroto Terasaki, Shozo Sonoda, Judith Blanz, Lucy Young, Taiji Sakamoto, Koh-Hei Sonoda, Paul Saftig, Tatsuro Ishibashi, Joan W. Miller, Guido Kroemer, and Demetrios G. Vavvas (Vol. 116, No. 47, November 19, 2019, p. 23724-23734).
www.pnas.org/content/116/47/23724
C. “Swim exercise in Caenorhabditis elegans extends neuromuscular and gut healthspan, enhances learning ability, and protects against neurodegeneration,” by Ricardo Laranjeiro, Girish Harinath, Jennifer E. Hewitt, Jessica H. Hartman, Mary Anne Royal, Joel N. Meyer, Siva A. Vanapalli, and Monica Driscoll (Vol. 116, No. 47, November 19, 2019, p. 23829-23839).
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September 30, 2019
CAAR – Public Library of Science (PLoS) Article – September 30, 2019
“Comorbidity of age-related macular degeneration with Alzheimer’s disease: A histopathologic case-control study,” by Gordon J. Smilnak, John R. Deans, P. Murali Doraiswamy, Sandra Stinnett, Heather E. Whitson, and Eleonora M. Lad (PLoS ONE 14(9): e0223199. doi.org/10.1371/journal.pone.0223199, XML, HTML, and .pdf format, 14p.).
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February 26, 2019
CAAR – Proceedings of the National Academy of Science Article Abstract – February 26, 2019
“Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice,” by Michael Landowski, Una Kelly, Mikael Klingeborn, Marybeth Groelle, Jin-Dong Ding, Daniel Grigsby, and Catherine Bowes Rickman (Vol. 116, No. 9, February 26, 2019, p. 3703-3711).
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November 1, 2018
CAAR – Public Library of Science (PLoS) Article – November 1, 2018
“The cost-effectiveness of systematic screening for age-related macular degeneration in South Korea,” by Ra Ho, Lina D. Song, Jin A. Choi, and Donghyun Jee (PLoS ONE 13(10): e0206690. doi.org/10.1371/journal.pone.0206690, XML, HTML, .pdf format, 14p.).
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August 9, 2018
CAAR – Public Library of Science (PLoS) Articles – August 9, 2018
A. “More push from your push-off: Joint-level modifications to modulate propulsive forces in old age,” by Michael G. Browne and Jason R. Franz ( PLoS ONE 13(8): e0201407. doi.org/10.1371/journal.pone.0201407, XML, HTML, and .pdf format, 14p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0201407
B. “Human pharyngeal microbiota in age-related macular degeneration,” by Eliza Xin Pei Ho, Chui Ming Gemmy Cheung, Shuzhen Sim, Collins Wenhan Chu, Andreas Wilm, Clarabelle Bitong Lin, Ranjana Mathur, Doric Wong, Choi Mun Chan, Mayuri Bhagarva, Augustinus Laude, Tock Han Lim, Tien Yin Wong, Ching Yu Cheng, Sonia Davila, and Martin Hibberd (PLoS ONE 13(8): e0201768. doi.org/10.1371/journal.pone.0201768, XML, HTML, and .pdf format, 16p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0201768
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August 1, 2018
CAAR – Public Library of Science (PLoS) Article – August 1, 2018
“Utility values for age-related macular degeneration patients in Korea,” by Seulggie Choi, Sang Min Park, and Donghyun Jee (PLoS ONE 13(7): e0201399. doi.org/10.1371/journal.pone.0201399, XML and .pdf format, 10p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0201399
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July 19, 2018
CAAR – Public Library of Science (PLoS) Articles – July 19, 2018
A. “Wishes and needs of community-dwelling older persons concerning general practice: A qualitative study,” by Sophie C. E. van Blijswijk, Claudia S. de Waard, Petra G. van Peet, Dagmar Keizer, Margaret von Faber, Margot W. M. de Waal, Wendy P. J. den Elzen, Jacobijn Gussekloo, and Jeanet W. Blom (PLoS ONE 13(7): e0200614. doi.org/10.1371/journal.pone.0200614, XML and .pdf format, 14p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0200614
B. “Age-related macular degeneration and progression of coronary artery calcium: The Multi-Ethnic Study of Atherosclerosis,” by Antonio B. Fernandez, Kevin D. Ballard, Tien Y. Wong, Mengye Guo, Robyn L. McClelland, Gregory Burke, Mary Frances Cotch, Barbara Klein, Matthew Allison, and Ronald Klein (PLoS ONE 13(7): e0201000. doi.org/10.1371/journal.pone.0201000, XML and .pdf format, 10p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0201000
C. “Amyloidogenic cross-seeding of Tau protein: Transient emergence of structural variants of fibrils,” by Bartosz Nizynski, Hanna Nieznanska, Robert Dec, Solomiia Boyko, Wojciech Dzwolak, and Krzysztof Nieznanski (PLoS ONE 13(7): e0201182. doi.org/10.1371/journal.pone.0201182, XML and .pdf format, 18p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0201182
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March 12, 2018
CAAR – Public Library of Science (PLoS) Article – March 12, 2018
“Investigating the modulation of genetic effects on late AMD by age and sex: Lessons learned and two additional loci,” by Thomas W. Winkler, Caroline Brandl, Felix Grassmann, Mathias Gorski, Klaus Stark, Julika Loss, Bernhard H. F. Weber, and Iris M. Heid, for the International Age-related Macular Degeneration Genomics Consortium (IAMDGC) (PLoS ONE 13(3): e0194321. doi.org/10.1371/journal.pone.0194321, XML, HTML, and .pdf format, 21p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0194321
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January 23, 2018
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – January 23, 2018
A. “Structural heterogeneity and intersubject variability of A{beta} in familial and sporadic Alzheimer’s disease,” by Carlo Condello, Thomas Lemmin, Jan Stöhr, Mimi Nick, Yibing Wu, Alison M. Maxwell, Joel C. Watts, Christoffer D. Caro, Abby Oehler, C. Dirk Keene, Thomas D. Bird, Sjoerd G. van Duinen, Lars Lannfelt, Martin Ingelsson, Caroline Graff, Kurt Giles, William F. DeGrado, and Stanley B. Prusiner (Vol. 115, No. 4, January 23, 2018, .pdf and HTML format, p. E782-E791). Note: PNAS is providing open access to the full-text of this article.
www.pnas.org/content/115/4/E782.abstract
B. “GBA1 deficiency negatively affects physiological {alpha}-synuclein tetramers and related multimers,” by Sangjune Kim, Seung Pil Yun, Saebom Lee, George Essien Umanah, Veera Venkata Ratnam Bandaru, Xiling Yin, Peter Rhee, Senthilkumar S. Karuppagounder, Seung-Hwan Kwon, Hojae Lee, Xiaobo Mao, Donghoon Kim, Akhilesh Pandey, Gabsang Lee, Valina L. Dawson, Ted M. Dawson, and Han Seok Ko (Vol. 115, No. 4, January 23, 2018, p. 798-803).
www.pnas.org/content/115/4/798.abstract
C. “CFH and ARMS2 genetic risk determines progression to neovascular age-related macular degeneration after antioxidant and zinc supplementation,” by Demetrios G. Vavvas, Kent W. Small, Carl C. Awh, Brent W. Zanke, Robert J. Tibshirani, and Rafal Kustra (Vol. 115, No. 4, January 23, 2018, .pdf and HTML format, p. E696-E704). Note: PNAS is providing open access to the full-text of this article.
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January 9, 2018
CAAR – Nature Medicine Article Abstracts – January 9, 2018
A. “Amyloid-{beta} plaques enhance Alzheimer’s brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation,” by Zhuohao He, Jing L. Guo, Jennifer D. McBride, Sneha Narasimhan, Hyesung Kim, Lakshmi Changolkar, Bin Zhang, Ronald J. Gathagan, Cuiyong Yue, Christopher Dengler, Anna Stieber, Magdalena Nitla, Douglas A. Coulter, Ted Abel, Kurt R. Brunden, John Q. Trojanowski & Virginia M-Y Lee (Vol. 24, No. 1, January 2018, p. 29-38).
www.nature.com/articles/nm.4443
B. “cGAS drives noncanonical-inflammasome activation in age-related macular degeneration,” by Nagaraj Kerur, Shinichi Fukuda, Daipayan Banerjee, Younghee Kim, Dongxu Fu, Ivana Apicella, Akhil Varshney, Reo Yasuma, Benjamin J. Fowler, Elmira Baghdasaryan, Kenneth M. Marion, Xiwen Huang, Tetsuhiro Yasuma, Yoshio Hirano, Vlad Serbulea, Meenakshi Ambati, Vidya L. Ambati, Yuji Kajiwara, Kameshwari Ambati, Shuichiro Hirahara, Ana Bastos-Carvalho, Yuichiro Ogura, Hiroko Terasaki, Tetsuro Oshika, Kyung Bo Kim, David R. Hinton, Norbert Leitinger, John C. Cambier, Joseph D.Buxbaum, M. Cristina Kenney, S. Michal Jazwinski, Hiroshi Nagai, Isao Hara, A. Phillip West, Katherine A. Fitzgerald, SriniVas R. Sadda, Bradley D. Gelfand & Jayakrishna Ambati (Vol. 24, No. 1, January 2018, p. 50-61).
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August 2, 2017
CAAR – Public Library of Science (PLoS) Article – August 2, 2017
“Cigarette smoke induced autophagy-impairment regulates AMD pathogenesis mechanisms in ARPE-19 cells,” by Viren Kumar Govindaraju, Manish Bodas, and Neeraj Vij ( PLoS ONE 12(8): e0182420. doi.org/10.1371/journal.pone.0182420, XML, HTML, and .pdf format, 17p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0182420
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May 30, 2017
CAAR – Proceedings of the National Academy of Sciences Article Abstract – May 30, 2017
“Involvement of a gut–retina axis in protection against dietary glycemia-induced age-related macular degeneration,” by Sheldon Rowan, Shuhong Jiang, Tal Korem, Jedrzej Szymanski, Min-Lee Chang, Jason Szelog, Christa Cassalman, Kalavathi Dasuri, Christina McGuire, Ryoji Nagai, Xue-Liang Du, Michael Brownlee, Naila Rabbani, Paul J. Thornalley, James D. Baleja, Amy A. Deik, Kerry A. Pierce, Justin M. Scott, Clary B. Clish, Donald E. Smith, Adina Weinberger, Tali Avnit-Sagi, Maya Lotan-Pompan, Eran Segal, and Allen Taylor (Vol. 114, No. 22, May 30, 2017, p. E4472-E4481).
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March 10, 2017
CAAR – Public Library of Science (PLoS) Article – March 10, 2017
“Age-related macular degeneration phenotypes are associated with increased tumor necrosis-alpha and subretinal immune cells in aged Cxcr5 knockout mice,” by Hu Huang, Ying Liu, Lei Wang, and Wen Li (PLoS ONE 12(3): e0173716. doi:10.1371/journal.pone.0173716, XML, HTML, and .pdf format, 23p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0173716
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November 28, 2016
CAAR – Public Library of Science (PLoS) Article – November 28, 2016
“Features of Age-Related Macular Degeneration in the General Adults and Their Dependency on Age, Sex, and Smoking: Results from the German KORA Study,” by Caroline Brandl, Valentin Breinlich, Klaus J. Stark, Sabrina Enzinger, Matthias Assenmacher, Matthias Olden, Felix Grassmann, Jochen Graw, Margit Heier, Annette Peters, Horst Helbig, Helmut Küchenhoff, Bernhard H. F. Weber, and Iris M. Heid (PLoS ONE 11(11): e0167181. doi:10.1371/journal.pone.0167181, HTML, XML, and .pdf format, 19p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0167181
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June 21, 2016
CAAR – Proceedings of the National Academy of Sciences Article Abstract – June 21, 2016
“Photodegradation of retinal bisretinoids in mouse models and implications for macular degeneration,” by Keiko Ueda, Jin Zhao, Hye Jin Kim, and Janet R. Sparrow (Vol. 113, No. 25, June 21, 2016, .pdf and HTML format, p. 6904–6909). Note: PNAS is providing open access to the full text of this article.
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February 29, 2016
CAAR – Public Library of Science (PLoS) Articles – February 29, 2016
A. “Prevalence and Genetic Characteristics of Geographic Atrophy among Elderly Japanese with Age-Related Macular Degeneration,” by Yoichi Sakurada, Seigo Yoneyama, Atsushi Sugiyama, Naohiko Tanabe, Wataru Kikushima, Fumihiko Mabuchi, Atsuki Kume, Takeo Kubota, and Hiroyuki Iijima (PLoS ONE 11(2): e0149978. doi:10.1371/journal.pone.0149978, XML, HTML, and .pdf format, 8p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0149978
B. “Relationship of Self-Rated Health to Stroke Incidence and Mortality in Older Individuals with and without a History of Stroke: A Longitudinal Study of the MRC Cognitive Function and Ageing (CFAS) Population,” by Nahal Mavaddat, Rianne van der Linde, Richard Parker, George Savva, Ann Louise Kinmonth, Carol Brayne, and Jonathan Mant (PLoS ONE 11(2): e0150178. doi:10.1371/journal.pone.0150178, XML, HTML, and .pdf format, 11p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0150178
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August 7, 2015
CAAR – Public Library of Science (PLoS) Article – August 7, 2015
“Association between Blood Lead Levels and Age-Related Macular Degeneration,” by Ho Sik Hwang, Seung Bum Lee, Donghyun Jee (PLoS ONE 10(8): e0134338. doi:10.1371/journal.pone.0134338, XML, HTML, and .pdf format, 15p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0134338
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July 29, 2015
CAAR – Public Library of Science (PLoS) Articles – July 29, 2015
A. “Did {alpha}-Synuclein and Glucocerebrosidase Coevolve? Implications for Parkinson’s Disease,” by James M. Gruschus (PLoS ONE 10(7): e0133863. doi:10.1371/journal.pone.0133863, XML, HTML, and .pdf format, 21p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0133863
B. “The Clinical Effectiveness and Cost-Effectiveness of Screening for Age-Related Macular Degeneration in Japan: A Markov Modeling Study,” by Hiroshi Tamura, Rei Goto, Yoko Akune, Yoshimune Hiratsuka, Shusuke Hiragi, and Masakazu Yamada (PLoS ONE 10(7): e0133628. doi:10.1371/journal.pone.0133628, XML, HTML, and .pdf format, 20p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0133628
C. “Enrichment of Minor Alleles of Common SNPs and Improved Risk Prediction for Parkinson’s Disease,” by Zuobin Zhu, Dejian Yuan, Denghui Luo, Xitong Lu, and Shi Huang (PLoS ONE 10(7): e0133421. doi:10.1371/journal.pone.0133421, XML, HTML, and .pdf format, 11p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0133421
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July 16, 2015
CAAR – Public Library of Science (PLoS) Articles – July 16, 2015
A. “Can Patients with Parkinson’s Disease Use Dry Powder Inhalers during Off Periods?” by M. Luinstra, A. W. F. Rutgers, H. Dijkstra, F. Grasmeijer, P. Hagedoorn, J. M. J. Vogelzang, H. W. Frijlink, and A. H. de Boer (PLoS ONE 10(7): e0132714. doi:10.1371/journal.pone.0132714, XML, HTML, and .pdf format, 12p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0132714
B. “Sleep Disorders in Parkinsonian and Nonparkinsonian LRRK2 Mutation Carriers,” by Claustre Pont-Sunyer, Alex Iranzo, Carles Gaig, Ana Fernández-Arcos, Dolores Vilas, Francesc Valldeoriola, Yaroslau Compta, Ruben Fernández-Santiago, Manel Fernández, Angels Bayes, Matilde Calopa, Pilar Casquero, Oriol de Fàbregues, Serge Jaumà, Victor Puente, Manel Salamero, Maria José Martí, Joan Santamaría, and Eduard Tolosa (PLoS ONE 10(7): e0132368. doi:10.1371/journal.pone.0132368, XML, HTML, and .pdf format, 20p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0132368
C. “Systemic and Ocular Long Pentraxin 3 in Patients with Age-Related Macular Degeneration,” by Helene Bae Juel, Carsten Faber, Lea Munthe-Fog, Simone Bastrup-Birk, Alexander Lynge Reese-Petersen, Mads Kruger Falk, Amardeep Singh, Torben Lykke Sorensen, Peter Garred, and Mogens Holst Nissen (PLoS ONE 10(7): e0132800. doi:10.1371/journal.pone.0132800, XML, HTML, and .pdf format, p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0132800
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June 9, 2015
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – June 9, 2015
A. “Regulation of age-related macular degeneration-like pathology by complement factor H,” by Christopher B. Toomey, Una Kelly, Daniel R. Saban, and Catherine Bowes Rickman (Vol. 112, No. 23, June 9, 2015, .pdf and HTML format, p. E3040–E3049). Note: PNAS is providing open access to the full-text of this article.
www.pnas.org/content/112/23/E3040.abstract
B. “Overlapping functions of stonin 2 and SV2 in sorting of the calcium sensor synaptotagmin 1 to synaptic vesicles,” by Natalie Kaempf, Gaga Kochlamazashvili, Dmytro Puchkov, Tanja Maritzen, Sandra M. Bajjalieh, Natalia L. Kononenko, and Volker Hauck (Vol. 112, No. 23, June 9, 2015, .pdf and HTML format, p. 7297–7302). Note: PNAS is providing open access to the full-text of this article.
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June 4, 2015
CAAR – Public Library of Science (PLoS) Article – June 4, 2015
“Dietary Supplement Enriched in Antioxidants and Omega-3 Protects from Progressive Light-Induced Retinal Degeneration,” by Khaoula Ramchani-Ben Othman, Christine Cercy, Mohamed Amri, Michel Doly, and Isabelle Ranchon-Cole (PLoS ONE 10(6): e0128395. doi:10.1371/journal.pone.0128395, XML, HTML, and .pdf format, 20p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0128395
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May 1, 2015
CAAR – Public Library of Science (PLoS) Article – May 1, 2015
“Age-Related Macular Degeneration Is Associated with Less Physical Activity among US Adults: Cross-Sectional Study,” by Paul D. Loprinzi, Bonnielin K. Swenor, and Pradeep Y. Ramulu (PLoS ONE 10(5): e0125394. doi:10.1371/journal.pone.0125394, XML, HTML, and .pdf format, 11p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0125394
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February 3, 2015
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – February 3, 2015
A. “Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye,” by Richard B. Thompson, Valentina Reffatto, Jacob G. Bundy, Elod Kortvely, Jane M. Flinn, Antonio Lanzirotti, Emrys A. Jones, David S. McPhail, Sarah Fearn, Karsten Boldt, Marius Ueffing, Savanjeet Guy Singh Ratu, Laurenz Pauleikhoff, Alan C. Bird, and Imre Lengyel (Vol. 112, No. 5, February 3, 2015, .pdf and HTML format, p. 1565-1570).
www.pnas.org/content/112/5/1565.abstract.html?etoc
B. “Endostatin: A novel inhibitor of androgen receptor function in prostate cancer,” by Joo Hyoung Lee, Tatyana Isayeva, Matthew R. Larson, Anandi Sawant, Ha-Ram Cha, Diptiman Chanda, Igor N. Chesnokov, and Selvarangan Ponnazhagan (Vol. 112, No. 5, February 3, 2015, .pdf and HTML format, p. 1392–1397).
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November 11, 2014
CAAR – Proceedings of the National Academy of Sciences Article Abstract – November 11, 2014
“DICER1/Alu RNA dysmetabolism induces Caspase-8–mediated cell death in age-related macular degeneration,” by Younghee Kim, Valeria Tarallo, Nagaraj Kerur, Tetsuhiro Yasuma, Bradley D. Gelfand, Ana Bastos-Carvalho, Yoshio Hirano, Reo Yasuma, Takeshi Mizutani, Benjamin J. Fowler, Shengjian Li, Hiroki Kaneko, Sasha Bogdanovich, Balamurali K. Ambati, David R. Hinton, William W. Hauswirth, Razqallah Hakem, Charles Wright, and Jayakrishna Ambati (Vol. 111, No. 45, November 12, 2014, p. 16082–16087).
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July 10, 2014
CAAR – US National Institutes of Health News Release – July 10, 2014
“Rehabilitation helps prevent depression from age-related vision loss” (Jul. 9, 2014).
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May 15, 2014
CAAR – Public Library of Science (PLoS) Articles – May 15, 2014
A. “Consumption of Green Tea, but Not Black Tea or Coffee, Is Associated with Reduced Risk of Cognitive Decline,” by Moeko Noguchi-Shinohara, Sohshi Yuki, Chiaki Dohmoto, Yoshihisa Ikeda, Miharu Samuraki, Kazuo Iwasa, Masami Yokogawa, Kimiko Asai, Kiyonobu Komai, Hiroyuki Nakamura, and Masahito Yamada (PLoS ONE 9(5): e96013. doi:10.1371/journal.pone.0096013, HTML, XML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0096013
B. “Proteomics of Vitreous Humor of Patients with Exudative Age-Related Macular Degeneration,” by Michael Janusz Koss, Janosch Hoffmann, Nauke Nguyen, Marcel Pfister, Harald Mischak, William Mullen, Holger Husi, Robert Rejdak, Frank Koch, Joachim Jankowski, Katharina Krueger, Thomas Bertelmann, Julie Klein, Joost P. Schanstra, and Justyna Siwy (PLoS ONE 9(5): e96895. doi:10.1371/journal.pone.0096895, HTML, XML, and .pdf format, p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0096895
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March 31, 2014
CAAR – Public Library of Science (PLoS) Article – March 31, 2014
“Age-Related Macular Degeneration and the Incidence of Cardiovascular Disease: A Systematic Review and Meta-Analysis,” by Juan Wu, Miki Uchino, Srinivas M. Sastry, and Debra A. Schaumberg (PLoS ONE 9(3): e89600. doi:10.1371/journal.pone.0089600, XML, HTML, and .pdf format, 11p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0089600
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October 22, 2013
CAAR – Proceedings of the National Academy of Sciences Article Abstract – October 22, 2013
“Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology,” by Peng Hu, Rolf Herrmann, Amanda Bednar, Peter Saloupis, Mary A. Dwyer, Ping Yang, Xiaoping Qi, Russell S. Thomas, Glenn J. Jaffe, Michael E. Boulton, Donald P. McDonnell, and Goldis Mal (Vol. 110, No. 43, October 22, 2013, .pdf and HTML format, p. E4069-E4078).
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October 11, 2013
CAAR – Lancet Article Abstracts – October 11, 2013
Note: Lancet requires free registration prior to providing access to content.
A. “Lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea and Clostridium difficile diarrhoea in older inpatients (PLACIDE): a randomised, double-blind, placebo-controlled, multicentre trial,” by Stephen J. Allen, Kathie Wareham, Duolao Wang, Caroline Bradley, Hayley Hutchings, Wyn Harris, Anjan Dhar, Helga Brown, Alwyn Foden, Michael B. Gravenor, and Dietrich Mack (Vol. 382, No. 9900, October 12, 2013, p. 1249-1257).
www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)61218-0/abstract
B. “Alternative treatments to inhibit VEGF in age-related choroidal neovascularisation: 2-year findings of the IVAN randomised controlled trial,” by Usha Chakravarthy, Simon P. Harding, Chris A. Rogers, Susan M. Downes, Andrew J. Lotery, Lucy A. Culliford, and Barnaby C. Reeves, on behalf of the IVAN study investigators (Vol. 382, No. 9900, October 12, 2013, p. 1258-1267).
www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)61501-9/abstract
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August 28, 2013
CAAR – Public Library of Science (PLoS) Article – August 28, 2013
“Metabolome-Wide Association Study of Neovascular Age-Related Macular Degeneration,” by Melissa P. Osborn, Youngja Park, Megan B. Parks, L. Goodwin Burgess, Karan Uppal, Kichun Lee, Dean P. Jones, and Milam A. Brantley Jr. (PLoS ONE 8(8): e72737. doi:10.1371/journal.pone.0072737, XML, HTML, and .pdf format, 10p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0072737
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August 26, 2013
CAAR – Public Library of Science (PLoS) Articles – August 26, 2013
A. “Elevated Alpha-Synuclein Impairs Innate Immune Cell Function and Provides a Potential Peripheral Biomarker for Parkinson’s Disease,” by Shyra J. Gardai, Wenxian Mao, Birgitt Schüle, Michael Babcock, Sue Schoebel, Carlos Lorenzana, Jeff Alexander, Sam Kim, Heather Glick, Kathryn Hilton, J. Kent Fitzgerald, Manuel Buttini, San-San Chiou, Lisa McConlogue, John P. Anderson, Dale B. Schenk, Frederique Bard, J. William Langston, Ted Yednock, and Jennifer A. Johnston (PLoS ONE 8(8): e71634. doi:10.1371/journal.pone.0071634, XML, HTML, and .pdf format, 21p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0071634
B. “Phototoxic Action Spectrum on a Retinal Pigment Epithelium Model of Age-Related Macular Degeneration Exposed to Sunlight Normalized Conditions,” by Emilie Arnault, Coralie Barrau, Celine Nanteau, Pauline Gondouin, Karine Bigot, Francoise Vienot, Emmanuel Gutman, Valerie Fontaine, Thierry Villette, Denis Cohen-Tannoudji, Jose-Alain Sahel, and Serge Picaud (PLoS ONE 8(8): e71398. doi:10.1371/journal.pone.0071398, XML, HTML, and .pdf format, 12p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0071398
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July 30, 2013
CAAR – Public Library of Science (PLoS) Articles – July 30, 2013
A. “Circulating miRNA Biomarkers for Alzheimer’s Disease,” by Pavan Kumar, Zoltan Dezso, Crystal MacKenzie, Judy Oestreicher, Sergei Agoulnik, Michael Byrne, Francois Bernier, Mamoru Yanagimachi, Ken Aoshima, and Yoshiya Oda (PLoS ONE 8(7): e69807. doi:10.1371/journal.pone.0069807, XML, HTML, and .pdf format, 10p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069807
B. “The Association between Plasma 25-Hydroxyvitamin D and Subgroups in Age-Related Macular Degeneration: A Cross-Sectional Study,” by Amardeep Singh, Mads Kruger Falk, Yousif Subhi, and Torben Lykke Sorensen (PLoS ONE 8(7): e70948. doi:10.1371/journal.pone.0070948, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0070948
C. “Drawing to Remember: External Support of Older Adults’ Eyewitness Performance,” by Coral J. Dando (PLoS ONE 8(7): e69937. doi:10.1371/journal.pone.0069937, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069937
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July 2, 2013
CAAR – Public Library of Science (PLoS) Article – July 2, 2013
“Interaction of Complement Factor H and Fibulin3 in Age-Related Macular Degeneration,” by M. Keith Wyatt, Jen-Yue Tsai, Sanghamitra Mishra, Maria Campos, Cynthia Jaworski, Robert N. Fariss, Steven L. Bernstein, and Graeme Wistow (PLoS ONE 8(6): e68088. doi:10.1371/journal.pone.0068088, XML, HTML, and .pdf format, p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068088
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April 3, 2013
CAAR – US National Institutes of Health Press Release – April 3, 2013
“Targeting cholesterol buildup in eye may slow age-related vision loss,” (April 3, 2013).
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February 21, 2013
CAAR – Public Library of Science (PLoS) Medicine Article – February 21, 2013
“Prevalence of Age-Related Macular Degeneration in Nakuru, Kenya: A Cross-Sectional Population-Based Study,” by Wanjiku Mathenge, Andrew Bastawrous, Tunde Peto, Irene Leung, Allen Foster, and Hannah Kuper (PLoS Med 10(2): e1001393. doi:10.1371/journal.pmed.1001393, XML, HTML, and .pdf format, 11p.).
www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001393
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September 24, 2012
CAAR – Public Library of Science (PLoS) Article – September 24, 2012
“Interleukin 27 Induces the Expression of Complement Factor H (CFH) in the Retina,” by Ahjoku Amadi-Obi, Cheng-Rong Yu, Ivy Dambuza, Sung-Hye Kim, Bernadette Marrero, and Charles E. Egwuagu (PLoS ONE 7(9): e45801. doi:10.1371/journal.pone.0045801, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0045801
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August 21, 2012
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – August 21, 2012
A. “Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids,” by Peter X. Shaw, Li Zhang, Ming Zhang, Hongjun Du, Ling Zhao, Clara Lee, Seanna Grob, Siok Lam Lim, Guy Hughes, Janet Lee, Matthew Bedell, Mark H. Nelson, Fang Lu, Martin Krupa, Jing Luo, Hong Ouyang, Zhidan Tu, Zhiguang Su, Jin Zhu, Xinran Wei, Zishan Feng, Yaou Duan, Zhenglin Yang, Henry Ferreyra, Dirk-Uwe Bartsch, Igor Kozak, Liangfang Zhang, Feng Lin, Hui Sun, Hong Feng, and Kang Zhang (Vol. 109, No. 34, Aug. 21, 2012, p. 13757-13762).
www.pnas.org/content/109/34/13757.abstract
B. “ERK1/2 activation is a therapeutic target in age-related macular degeneration,” by Sami Dridi, Yoshio Hirano, Valeria Tarallo, Younghee Kim, Benjamin J. Fowler, Balamurali K. Ambati, Sasha Bogdanovich, Vince A. Chiodo, William W. Hauswirth, Jennifer F. Kugel, James A. Goodrich, Steven L. Ponicsan, David R. Hinton, Mark E. Kleinman, Judit Z. Baffi, Bradley D. Gelfand, and Jayakrishna Ambati (Vol. 109, No. 34, Aug. 21, 2012, p. 13781-13786).
www.pnas.org/content/109/34/13781.abstract
C. “Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer’s disease,” by Álvaro O. Ardiles, Cheril C. Tapia-Rojas, Madhuchhanda Mandal, Frédéric Alexandre, Alfredo Kirkwood, Nibaldo C. Inestrosa, and Adrian G. Palacios (Vol. 109, No. 34, Aug. 21, 2012, p. 13835-13840).
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August 13, 2012
CAAR – Tables of Contents – August 13, 2012
American Journal of Epidemiology (Vol. 176, No. 4, Aug. 15, 2012).
aje.oxfordjournals.org/content/176/4.toc?etoc
Archives of Gerontology and Geriatrics (Vol. 55, No. 2, September/October 2012).
www.sciencedirect.com/science/journal/01674943
Journal of the American Geriatrics Society (Vol. 60, No. 8, August 2012).
onlinelibrary.wiley.com/doi/10.1111/jgs.2012.60.issue-8/issuetoc
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May 8, 2012
CAAR – Nature Medicine Article Abstract – May 8, 2012
“NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components,” by Sarah L. Doyle, Matthew Campbell, Ema Ozaki, Robert G. Salomon, Andres Mori, Paul F. Kenna, Gwyneth Jane Farrar, Anna-Sophia Kiang, Marian M. Humphries, Ed C. Lavelle, Luke A. J. O’Neill, Joe G. Hollyfield & Peter Humphries (Vol. 18, No. 5, May 2012, p. 791-798).
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May 7, 2012
CAAR – Lancet Series Abstract – May 7, 2012
Note: Lancet requires free registration before providing articles.
“Age-related macular degeneration,” by Laurence S. Lim, Paul Mitchell, Johanna M. Seddon, Frank G. Holz, and Tien Y. Wong (Vol. 379, No. 9827, May 5, 2012, p. 1728-1738).
www.lancet.com/journals/lancet/article/PIIS0140-6736%2812%2960282-7/abstract
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April 30, 2012
CAAR – US National Institutes of Health Press Release – April 30, 2012
“Avastin and Lucentis are equivalent in treating age-related macular degeneration,” (April 30, 2012).
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April 23, 2012
CAAR – US Department of Health and Human Services, Office of Inspector General Report – April 23, 2012
“Medicare Payments for Drugs Used To Treat Wet Age Related Macular Degeneration,” (OEI-03-10-00360, April 2012, .pdf format, 18p.).
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February 24, 2012
CAAR – Lancet Article Abstract – February 24, 2012
Note: Lancet requires free registration before providing content. “Embryonic stem cell trials for macular degeneration: a preliminary report,” by Steven D Schwartz, Jean-Pierre Hubschman, Gad Heilwell, Valentina Franco-Cardenas, Carolyn K Pan, Rosaleen M Ostrick, Edmund Mickunas, Roger Gay, Irina Klimanskaya, and Robert Lanza (Vol. 379, No. 9817, February 25, 2012, p. 713-720).
www.thelancet.com/journals/lancet/article/PIIS0140-6736%2812%2960028-2/abstract
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