July 28, 2021

CAAR – Public Library of Science (PLoS) Articles – July 28, 2021

Filed under: Reports and Articles — Tags: , , — admin @ 5:17 pm

A. “Prevalence of loneliness amongst older people in high-income countries: A systematic review and meta-analysis,” by Kavita Chawla, Tafadzwa Patience Kunonga, Daniel Stow, Robert Barker, Dawn Craig, and Barbara Hanratty (PLoS ONE 16(7): e0255088., XML, HTML, and .pdf format, 15p.).

B. “The Mean Unfulfilled Lifespan (MUL): A new indicator of the impact of mortality shocks on the individual lifespan, with application to mortality reversals induced by COVID-19,” by Patrick Heuveline ( PLoS ONE 16(7): e0254925., HTML, XML, and .pdf format, 16.).

July 2, 2021

CAAR – Demographic Research Article – July 2, 2021

Filed under: Reports and Articles — Tags: — admin @ 5:55 pm

Probabilistic forecasting of maximum human lifespan by 2100 using Bayesian population projections,” by Michael Pearce, Adrian E. Raftery (Vol. 44, Article 52, June 2021, .pdf format, p. 1271-1294).

December 1, 2020

CAAR – Proceedings of the National Academy of Science Article Abstract – December 1, 2020

Global associations between macronutrient supply and age-specific mortality,” by Alistair M. Senior, Shinichi Nakagawa, David Raubenheimer, and Stephen J. Simpson (Vol. 117, No. 48, December 1, 2020, p. 30824-30835).

April 19, 2017

CAAR – Proceedings of the National Academy of Science Article Abstract – April 19, 2017

Prenatal loss of father during World War One is predictive of a reduced lifespan in adulthood,” by Nicolas Todd, Alain-Jacques Valleron, and Pierre Bougnères (Vol. 114, No. 16, April 18, 2017, p. 4201–4206).

October 12, 2016

CAAR – Nature Letter Abstracts – October 12, 2016

Filed under: Reports and Articles — Tags: , , , — admin @ 5:15 pm

A. “Evidence for a limit to human lifespan,” by Xiao Dong, Brandon Milholland & Jan Vijg (Vol. 538, No. 7624, October 13, 2016, p. 257-259).

B. “Tissue-specific mutation accumulation in human adult stem cells during life,” by Francis Blokzijl, Joep de Ligt, Myrthe Jager, Valentina Sasselli, Sophie Roerink, Nobuo Sasaki, Meritxell Huch, Sander Boymans, Ewart Kuijk, Pjotr Prins, Isaac J. Nijman, Inigo Martincorena, Michal Mokry, Caroline L. Wiegerinck, Sabine Middendorp, Toshiro Sato, Gerald Schwank, Edward E. S. Nieuwenhuis, Monique M. A. Verstegen, Luc J. W. van der Laan, Jeroen de Jonge, Jan N. M. IJzermans, Robert G. Vries, Marc van de Wetering, Michael R. Stratton, Hans Clevers, Edwin Cuppen & Ruben van Boxtel (Vol. 538, No. 7624, October 13, 2016, p. 260-264).

February 2, 2016

CAAR – Proceedings of the National Academy of Sciences Article Abstracts – February 2, 2016

A. “Nicastrin functions to sterically hinder {gamma}-secretase–substrate interactions driven by substrate transmembrane domain,” by David M. Bolduc, Daniel R. Montagna, Yongli Gu, Dennis J. Selkoe, and Michael S. Wolfe (Vol. 113, No. 5, February 2, 2016, p. E509-E518).

B. “Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila,” by Sonita Afschar, Janne M. Toivonen, Julia Marianne Hoffmann, Luke Stephen Tain, Daniela Wieser, Andrew John Finlayson, Yasmine Driege, Nazif Alic, Sahar Emran, Julia Stinn, Jenny Froehlich, Matthew D. Piper, and Linda Partridge (Vol. 113, No. 5, February 2, 2016, p. 1321-1326).

C. “Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice,” by Roberta Marongiu, Margarita Arango-Lievano, Veronica Francardo, Peter Morgenstern, Xiaoqun Zhang, M. Angela Cenci, Per Svenningsson, Paul Greengard, and Michael G. Kaplitt (Vol. 113, No. 5, February 2, 2016, p. 1423-1428).

D. “p11 modulates L-DOPA therapeutic effects and dyskinesia via distinct cell types in experimental Parkinsonism,” by Nicoletta Schintu, Xiaoqun Zhang, Alexandra Alvarsson, Roberta Marongiu, Michael G. Kaplitt, Paul Greengard, and Per Svenningsson (Vol. 113, No. 5, February 2, 2016, p. 1429-1434).

November 6, 2014

CAAR – US National Center for Health Statistics Report – November 6, 2014

Filed under: Reports and Articles — Tags: , — admin @ 4:59 pm

United States Life Tables, 2010,” by Elizabeth Arias (National Vital Statistics Report, Vol. 63, No. 7, November 2014, .pdf format, 62p.).

November 15, 2013

CAAR – US National Institute on Aging News Release – November 15, 2013

Filed under: Reports and Articles — Tags: — admin @ 4:42 pm

Diabetes drug increases lifespan of male mice, shows smaller effect in females,” (November 15, 2013).

September 18, 2013

CAAR – Public Library of Science (PLoS) Articles – September 18, 2013

Filed under: Reports and Articles — Tags: , , , , — admin @ 4:31 pm

A. “Diets Based on Virgin Olive Oil or Fish Oil but Not on Sunflower Oil Prevent Age-Related Alveolar Bone Resorption by Mitochondrial-Related Mechanisms,” by Pedro Bullon, Maurizio Battino, Alfonso Varela-Lopez, Patricia Perez-Lopez, Sergio Granados-Principal, Maria C. Ramirez-Tortosa, Julio J. Ochoa, Mario D. Cordero, Adrian Gonzalez-Alonso, César L. Ramirez-Tortosa, Corrado Rubini, Antonio Zizzi, and Jose L. Quiles (PLoS ONE 8(9): e74234. doi:10.1371/journal.pone.0074234, XML, HTML, and .pdf format, 11p.).

B. “Area-Specific Alterations of Synaptic Plasticity in the 5XFAD Mouse Model of Alzheimer’s Disease: Dissociation between Somatosensory Cortex and Hippocampus,” by Nadine Crouzin, Kevin Baranger, Melanie Cavalier, Yannick Marchalant, Catherine Cohen-Solal, François S. Roman, Michel Khrestchatisky, Santiago Rivera, Francois Feron, and Michel Vignes (PLoS ONE 8(9): e74667. doi:10.1371/journal.pone.0074667, XML, HTML, and .pdf format, 9p.).

C. “Rare Variants in Calcium Homeostasis Modulator 1 (CALHM1) Found in Early Onset Alzheimer’s Disease Patients Alter Calcium Homeostasis,” by Fanny Rubio-Moscardo, Nuria Seto-Salvia, Marta Pera, Monica Bosch-Morato, Cristina Plata, Olivia Belbin, Gemma Gene, Oriol Dols-Icardo, Martin Ingelsson, Seppo Helisalmi, Hilkka Soininen, Mikko Hiltunen, Vilmantas Giedraitis, Lars Lannfelt, Ana Frank, Ma Jesus Bullido, Onofre Combarros, Pascual Sanchez-Juan, Merce Boada, Lluís Tarraga, Pau Pastor, Jordi Perez-Tur, Miquel Baquero, Jose L. Molinuevo, Raquel Sanchez-Valle, Pablo Fuentes-Prior, Juan Fortea, Rafael Blesa, Francisco J. Munoz, Alberto Lleo, Miguel A. Valverde, and Jordi Clarimon (PLoS ONE 8(9): e74203. doi:10.1371/journal.pone.0074203, XML, HTML, and .pdf format, 8p.).

D. “Prevalence of Major Chronic Conditions among Older Chinese Adults: The Study on Global AGEing and Adult Health (SAGE) Wave 1,” by Fan Wu, Yanfei Guo, Paul Kowal, Yong Jiang, Min Yu, Xinjian Li, Yang Zheng, and Jiying Xu (PLoS ONE 8(9): e74176. doi:10.1371/journal.pone.0074176, XML, HTML, and .pdf format, 8p.).

E. “Mitochondrial Inverted Repeats Strongly Correlate with Lifespan: mtDNA Inversions and Aging,” by Jiang-Nan Yang, Andrei Seluanov, and Vera Gorbunova (PLoS ONE 8(9): e73318. doi:10.1371/journal.pone.0073318, XML, HTML, and .pdf format, 10p.).

F. “Effects of apoE Deficiency and Occlusal Disharmony on Amyloid-Beta Production and Spatial Memory in Rats,” by Daisuke Ekuni, Yasumasa Endo, Takaaki Tomofuji, Tetsuji Azuma, Koichiro Irie, Kenta Kasuyama, and Manabu Morita (PLoS ONE 8(9): e74966. doi:10.1371/journal.pone.0074966, XML, HTML, and .pdf format, 8p.).


July 30, 2013

CAAR – US National Institutes of Health Press Release – July 30, 2013

Filed under: Reports and Articles — Tags: , — admin @ 4:24 pm

NIH researchers find diabetes drug extends health and lifespan in mice,” (July 30, 2013).

June 26, 2012

CAAR – US National Institute on Aging Press Release – June 26, 2012

Filed under: Reports and Articles — Tags: — admin @ 4:18 pm

Understanding of mTOR pathway and lifespan refined in new study,” (June 25, 2012).

February 1, 2012

CAAR – Proceedings of the National Academy of Sciences Articles, Article Abstract – February 1, 2012

A. “Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression,” by Justin M. Drake, Nicholas A. Graham, Tanya Stoyanova, Amir Sedghi, Andrew S. Goldstein, Houjian Cai, Daniel A. Smith, Hong Zhang, Evangelia Komisopoulou, Jiaoti Huang, Thomas G. Graeber, and Owen N. Witte (Vol. 109, No. 5, Jan. 31, 2012, HTML and .pdf format, p. 1643-1648). This article is available free of charge.

B. “Telomere length in early life predicts lifespan,” by  Britt J. Heidinger, Jonathan D. Blount, Winnie Boner, Kate Griffiths, Neil B. Metcalfe, and Pat Monaghan Vol. 109, No. 5, Jan. 31, 2012, HTML and .pdf format, p. 1743-1748). This article is available free of charge.

B. “Antagonists of growth hormone-releasing hormone inhibit growth of androgen-independent prostate cancer through inactivation of ERK and Akt kinases,” by Ferenc G. Rick, Andrew V. Schally, Luca Szalontay, Norman L. Block, Karoly Szepeshazi, Mehrdad Nadji, Marta Zarandi, Florian Hohla, Stefan Buchholz, and Stephan Seitz (Vol. 109, No. 5, Jan. 31, 2012, p. 1655-1660).

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