Note: Check with your organization’s library for availability. “APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline,” by Axel Montagne, Daniel A. Nation, Abhay P. Sagare, Giuseppe Barisano, Melanie D. Sweeney, Ararat Chakhoyan, Maricarmen Pachicano, Elizabeth Joe, Amy R. Nelson, Lina M. D’Orazio, David P. Buennagel, Michael G. Harrington, Tammie L. S. Benzinger, Anne M. Fagan, John M. Ringman, Lon S. Schneider, John C. Morris, Eric M. Reiman, Richard J. Caselli, Helena C. Chui, Julia TCW, Yining Chen, Judy Pa, Peter S. Conti, Meng Law, Arthur W. Toga & Berislav V. Zlokovic (Vol. 581, No. 7806, May 7, 2020, p. 71-76).
May 6, 2020
May 24, 2019
CAAR – US Centers for Disease Control and Prevention Article – May 24, 2019
“Vision Impairment and Subjective Cognitive Decline–Related Functional Limitations — United States, 2015–2017,” by Sharon Saydah, Robert B. Gerzoff, Christopher A. Taylor, Joshua R. Ehrlich, and Jinan Saaddine (Morbidity and Mortality Weekly Report, Vol. 68, No. 20, May 24, 2019, .pdf and HTML format, p. 453-457).
Comments Off on CAAR – US Centers for Disease Control and Prevention Article – May 24, 2019
March 19, 2019
CAAR – Proceedings of the National Academies of Sciences Article Abstracts – March 19, 2019
A. “Advantaged socioeconomic conditions in childhood are associated with higher cognitive functioning but stronger cognitive decline in older age,” by Marja J. Aartsen, Boris Cheval, Stefan Sieber, Bernadette W. Van der Linden, Rainer Gabriel, Delphine S. Courvoisier, Idris Guessous, Claudine Burton-Jeangros, David Blane, Andreas Ihle, Matthias Kliegel, and Stephane Cullati (Vol. 116, No. 12, March 19, 2019, p. 5478-5486).
www.pnas.org/content/116/12/5478
B. “Parkinson’s disease-linked D620N VPS35 knockin mice manifest tau neuropathology and dopaminergic neurodegeneration,” by Xi Chen, Jennifer K. Kordich, Erin T. Williams, Nathan Levine, Allyson Cole-Strauss, Lee Marshall, Viviane Labrie, Jiyan Ma, Jack W. Lipton, and Darren J. Moore (Vol. 116, No. 12, March 19, 2019, p. 5765-5774). Note: PNAS is providng open access to the full-text of this article.
Comments Off on CAAR – Proceedings of the National Academies of Sciences Article Abstracts – March 19, 2019
March 18, 2019
CAAR – Public Library of Science (PLoS) Articles – March 18, 2019
A. “Age and cognitive decline in the UK Biobank,” by Marilyn C. Cornelis, Yamin Wang, Thomas Holland, Puja Agarwal, Sandra Weintraub, and Martha Clare Morris (PLoS ONE 14(3): e0213948. doi.org/10.1371/journal.pone.0213948, XML, HTML, and .pdf format, 16p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0213948
B. “Breathlessness and incidence of COPD, cardiac events and all-cause mortality: A 44-year follow-up from middle age throughout life,” by Jacob Sandberg, Gunnar Engstrom, and Magnus Ekstrom (PLoS ONE 14(3): e0214083. doi.org/10.1371/journal.pone.0214083, XML, HTML, and .pdf format, 11p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0214083
Comments Off on CAAR – Public Library of Science (PLoS) Articles – March 18, 2019
November 5, 2018
CAAR – National Bureau of Economic Research Working Paper – November 5, 2018
Links to an abstract are available. For full text availability check your organization’s library. “The Effect of Physical and Cognitive Decline at Older Ages on Job Mismatch and Retirement,” by Peter Hudomiet, Michael D. Hurd, Susann Rohwedder, and Robert J. Willis (w25229, October 2018, .pdf format, 75p.).
Comments Off on CAAR – National Bureau of Economic Research Working Paper – November 5, 2018
October 26, 2018
CAAR – Nature Letter Abstract – October 26, 2018
“Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline,” by Tyler J. Bussian, Asef Aziz, Charlton F. Meyer, Barbara L. Swenson, Jan M. van Deursen & Darren J. Baker (Vol. 562, No. 7728, October 25, 2018, p. ).
Comments Off on CAAR – Nature Letter Abstract – October 26, 2018
September 11, 2018
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – September 11, 2018
A. “Multidimensional comparison of countries’ adaptation to societal aging,” by Cynthia Chen, Dana P. Goldman, Julie Zissimopoulos, John W. Rowe, and Research Network on an Aging Society (Vol. 115, No. 37, September 12, 2018, p. 9169-9174).
www.pnas.org/content/115/37/9169
B. “The impact of exposure to air pollution on cognitive performance,” by Xin Zhang, Xi Chen, and Xiaobo Zhang (Vol. 115, No. 37, September 12, 2018, p. 9193-9197).
Comments Off on CAAR – Proceedings of the National Academy of Sciences Article Abstracts – September 11, 2018
July 17, 2018
CAAR – US Centers for Disease Control Article – July 17, 2018
“Subjective Cognitive Decline Among Adults Aged => 45 Years — United States, 2015–2016,” by Christopher A. Taylor, Erin D. Bouldin, and Lisa C. McGuire (Morbidity and Mortality Weekly Report, Vol. 67, No. 27, July 13, 2018, .pdf and HTML format, p. 753-757).
www.cdc.gov/mmwr/volumes/67/wr/mm6727a1.htm?s_cid=mm6727a1_w
Comments Off on CAAR – US Centers for Disease Control Article – July 17, 2018
April 5, 2018
CAAR – Public Library of Science (PLoS) Medicine Articles – April 5, 2018
A. “Cerebral white matter disease and functional decline in older adults from the Northern Manhattan Study: a longitudinal cohort study,” by Mandip S. Dhamoon, Ying-Kuen Cheung, Yeseon Moon, Janet DeRosa, Ralph Sacco, Mitchell S.V. Elkind, and Clinton B. Wright (PLoS Med 15(3): e1002529. doi.org/10.1371/journal.pmed.1002529, XML, HTML, and .pdf format, 14p.).
journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002529
B. “Trajectories of functional decline in older adults with neuropsychiatric and cardiovascular multimorbidity: A Swedish cohort study,” by Davide L. Vetrano, Debora Rizzuto, Amaia Calderón-Larranaga, Graziano Onder, Anna-Karin Welmer, Roberto Bernabei, Alessandra Marengoni, and Laura Fratiglioni (PLoS Med 15(3): e1002503. doi.org/10.1371/journal.pmed.1002503, XML, HTML, and .pdf format, 15p.).
journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002503
Comments Off on CAAR – Public Library of Science (PLoS) Medicine Articles – April 5, 2018
February 20, 2018
CAAR – Public Library of Science (PLoS) Articles – February 20, 2018
A. “Factors associated with occasional and recurrent falls in Mexican community-dwelling older people,” by Marcela Agudelo-Botero, Liliana Giraldo-Rodríguez, Juana Catalina Murillo-González, Dolores Mino-Leon, and Esteban Cruz-Arenas (PLoS ONE 13(2): e0192926.
doi.org/10.1371/journal.pone.0192926, XML, HTML, and .pdf format, 12p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0192926
B. “Apolipoprotein E genotype does not moderate the associations of depressive symptoms, neuroticism and allostatic load with cognitive ability and cognitive aging in the Lothian Birth Cohort 1936,” by Zander Crook, Tom Booth, Simon R. Cox, Janie Corley, Dominika Dykiert, Paul Redmond, Alison Pattie, Adele M. Taylor, Sarah E. Harris, John M. Starr, and Ian J. Deary (PLoS ONE 13(2): e0192604. doi.org/10.1371/journal.pone.0192604, XML, HTML, and .pdf format, 20p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0192604
Comments Off on CAAR – Public Library of Science (PLoS) Articles – February 20, 2018
June 15, 2017
CAAR – Journal of the American Medical Association Article – June 15, 2017
Note: The link below is to the table of contents for the current issue of JAMA (Vol. 317, No. 22, June 13, 2017). Check with your organization’s information center for availability.
jamanetwork.com/journals/jama/issue/317/22
“Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons,” by Michael C. Donohue, Reisa A. Sperling, Ronald Petersen, Chung-Kai Sun, Michael W. Weiner, and Paul S. Aisen, for the Alzheimer’s Disease Neuroimaging Initiative (p. 2305-2316).
Comments Off on CAAR – Journal of the American Medical Association Article – June 15, 2017
April 12, 2017
CAAR – Lancet Neurology Article Abstracts – April 12, 2017
A. “Serotonin and dopamine transporter PET changes in the premotor phase of LRRK2 parkinsonism: cross-sectional studies,” by Dr. Daryl J. Wile, Pankaj A. Agarwal, Prof. Michael Schulzer, Edwin Mak, Katherine Dinelle, Elham Shahinfard, Nasim Vafai, Kazuko Hasegawa, Prof. Jing Zhang, Jessamyn McKenzie, Nicole Neilson, Audrey Strongosky, Prof. Ryan J. Uitti, Mark Guttman, Cyrus P. Zabetian, Prof. Yu-Shin Ding, Mike Adam, Prof. Jan Aasly, Prof. Zbigniew K. Wszolek, Prof. Matthew Farrer, Prof. Vesna Sossi, and Prof. A. Jon Stoessl (Vol. 16, No. 5, May 2017, p. 351–359).
www.thelancet.com/journals/laneur/article/PIIS1474-4422(17)30056-X/abstract
B. “Effect of long-term omega 3 polyunsaturated fatty acid supplementation with or without multidomain intervention on cognitive function in elderly adults with memory complaints (MAPT): a randomised, placebo-controlled trial,” by Sandrine Andrieu, Sophie Guyonnet, Nicola Coley, Christelle Cantet, Marc Bonnefoy, Serge Bordes, Lawrence Bories, Marie-Noelle Cufi, Thierry Dantoine, Jean-François Dartigues, Françoise Desclaux, Audrey Gabelle, Yannick Gasnier, Alain Pesce, Kristel Sudres, Jacques Touchon, Philippe Robert, Olivier Rouaud, Philippe Legrand, Pierre Payoux, Jean-Paul Caubere, Michael Weiner, Isabelle Carrié, Pierre-Jean Ousset, and Bruno Vellas for the MAPT Study Group (Vol. 16, No. 5, May 2017, p. 377–389).
www.thelancet.com/journals/laneur/article/PIIS1474-4422(17)30040-6/abstract
Comments Off on CAAR – Lancet Neurology Article Abstracts – April 12, 2017
January 5, 2016
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – January 5, 2016
A. “Human-specific derived alleles of CD33 and other genes protect against postreproductive cognitive decline,” by Flavio Schwarz, Stevan A. Springer, Tasha K. Altheide, Nissi M. Varki, Pascal Gagneux, and Ajit Varki (Vol. 113, No. 1, January 5, 2016, p. 75-79).
www.pnas.org/content/113/1/74.abstract
B. “Effects of aging on circadian patterns of gene expression in the human prefrontal cortex,” by Cho-Yi Chen, Ryan W. Logan, Tianzhou Ma, David A. Lewis, George C. Tseng, Etienne Sibille, and Colleen A. McClung (Vol. 113, No. 1, January 5, 2016, p. 206-211).
Comments Off on CAAR – Proceedings of the National Academy of Sciences Article Abstracts – January 5, 2016
November 16, 2015
CAAR – Public Library of Science (PLoS) Article – November 16, 2015
“An Event Related Potentials Study of the Effects of Age, Load and Maintenance Duration on Working Memory Recognition,” by Diego Pinal, Montserrat Zurron, and Fernando Díaz (PLoS ONE 10(11): e0143117. doi:10.1371/journal.pone.0143117, XML, HTML, and .pdf format, 19p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0143117
Comments Off on CAAR – Public Library of Science (PLoS) Article – November 16, 2015
September 23, 2015
CAAR – Public Library of Science (PLoS) Article – September 23, 2015
“Prevalence of Dementia and Cognitive Complaints in the Context of High Cognitive Reserve: A Population-Based Study,” by Magali Perquin, Nico Diederich, Jessica Pastore, Marie-Lise Lair, Saverio Stranges, and Michel Vaillant, on behalf of the MemoVie Group (PLoS ONE 10(9): e0138818. doi:10.1371/journal.pone.0138818, XML, HTML, and .pdf format, 19p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0138818
Comments Off on CAAR – Public Library of Science (PLoS) Article – September 23, 2015
September 9, 2015
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – September 9, 2015
A. “Effect of aging on muscle mitochondrial substrate utilization in humans,” by Kitt Falk Petersen, Katsutaro Morino, Tiago C. Alves, Richard G. Kibbey, Sylvie Dufour, Saki Sono, Peter S. Yoo, Gary W. Cline, and Gerald I. Shulman (Vol. 112, No. 36, September 8, 2015, .pdf and HTML format, p. 11330-11334). Note: PNAS is providing open access to the full-text of this article.
www.pnas.org/content/112/36/11330.abstract
B. “Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1{beta} in the aged hippocampus,” by G. Aleph Prieto, Shikha Snigdha, David Baglietto-Vargas, Erica D. Smith, Nicole C. Berchtold, Liqi Tong, Dariush Ajami, Frank M. LaFerla, Julius Rebek Jr., and Carl W. Cotman (Vol. 112, No. 36, September 8, 2015, .pdf and HTML format, p. E5078-E5087). Note: PNAS is providing open access to the full-text of this article.
Comments Off on CAAR – Proceedings of the National Academy of Sciences Article Abstracts – September 9, 2015
September 3, 2015
CAAR – Public Library of Science (PLoS) Articles – September 3, 2015
A. “Gender-Specific Differences in the Relationship between Autobiographical Memory and Intertemporal Choice in Older Adults,” by Maayke Seinstra, Katharina Grzymek, and Tobias Kalenscher (PLoS ONE 10(9): e0137061. doi:10.1371/journal.pone.0137061, XML, HTML, and .pdf format, 22p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0137061
B. “Comparative Incidence of Conformational, Neurodegenerative Disorders,” by Jesús de Pedro-Cuesta, Alberto Rábano, Pablo Martínez-Martín, María Ruiz-Tovar, Enrique Alcalde-Cabero, Javier Almazán-Isla, Fuencisla Avellanal, and Miguel Calero (PLoS ONE 10(9): e0137342. doi:10.1371/journal.pone.0137342, XML, HTML, and .pdf format, 15p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0137342
Comments Off on CAAR – Public Library of Science (PLoS) Articles – September 3, 2015
July 9, 2015
CAAR – Journal of the American Medical Association Articles – July 9, 2015
Note: The link below is to the table of contents for the current issue of JAMA (Vol. 314, No. 1, July 7, 2015). Check with your organizations information for availability.
“Trajectory of Cognitive Decline After Incident Stroke,” by Deborah A. Levine, Andrzej T. Galecki, Kenneth M. Langa, Frederick W. Unverzagt, Mohammed U. Kabeto, Bruno Giordani, and Virginia G. Wadley (p. 41-51).
jama.jamanetwork.com/issue.aspx?journalid=67&issueid=934202&direction=P
Comments Off on CAAR – Journal of the American Medical Association Articles – July 9, 2015
June 25, 2015
CAAR – Public Library of Science (PLoS) Articles – June 25, 2015
A. “Influence of Retirement on Adherence to Statins in the Insurance Medicine All-Sweden Total Population Data Base,” by Heli Halava, Hugo Westerlund, Maarit Jaana Korhonen, Jaana Pentti, Mika Kivimaki, Linnea Kjeldgard, Kristina Alexanderson, and Jussi Vahtera (PLoS ONE 10(6): e0130901. doi:10.1371/journal.pone.0130901, HTML, XML, and .pdf format, 14p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0130901
B. “Effect of APOE and CD33 on Cognitive Decline,” by Kathleen M. Hayden, Michael W. Lutz, Maragatha Kuchibhatla, Cassandra Germain, and Brenda L. Plassman (PLoS ONE 10(6): e0130419. doi:10.1371/journal.pone.0130419, XML, HTML, and .pdf format, 10p.).
journals.plos.org/plosone/article?id=10.1371/journal.pone.0130419
Comments Off on CAAR – Public Library of Science (PLoS) Articles – June 25, 2015
March 31, 2015
CAAR – Center for Retirement Research at Boston College Issue Brief – March 31, 2015
“Are Cognitive Constraints a Barrier to Annuitization?” by Jeffrey R. Brown, Arie Kapteyn, Erzo F.P. Luttmer and Olivia S. Mitchell (IB 15-06, March 2015, .pdf format, 7p.).
crr.bc.edu/briefs/are-cognitive-constraints-a-barrier-to-annuitization/
Comments Off on CAAR – Center for Retirement Research at Boston College Issue Brief – March 31, 2015
March 17, 2015
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – March 17, 2015
A. “Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH Open,” by Shangyu Dang, Shenjie Wu, Jiawei Wang, Hongbo Li, Min Huang, Wei He, Yue-Ming Li, Catherine C. L. Wong, and Yigong Shi (Vol. 112, No. 11, March 17, 2015, .pdf and HTML format, p. 3344–3349). Note: PNAS is providing open access to the full-text of this article.
www.pnas.org/content/112/11/3344.abstract.html?etoc
B. “Insulin resistance in brain alters dopamine turnover and causes behavioral disorders,” by Andre Kleinridders, Weikang Cai, Laura Cappellucci, Armen Ghazarian, William R. Collins, Sara G. Vienberg, Emmanuel N. Pothos, and C. Ronald Kahn (Vol. 112, No. 11, March 17, 2015, p. 3463–3468).
Comments Off on CAAR – Proceedings of the National Academy of Sciences Article Abstracts – March 17, 2015
December 30, 2014
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – December 30, 2014
A. “Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors,” by Jin Zhang, Enshun Xu, Cong Ren, Wensheng Yan, Min Zhang, Mingyi Chen, Robert D. Cardiff, Denise M. Imai, Erik Wisner, and Xinbin Chen (Vol. 111, No. 52, December 30, 2014, p. 18637–18642).
www.pnas.org/content/111/52/18637.abstract.html?etoc
B. “Glutamatergic regulation prevents hippocampal-dependent age-related cognitive decline through dendritic spine clustering,” by Ana C. Pereira, Hilary K. Lambert, Yael S. Grossman, Dani Dumitriu, Rachel Waldman, Sophia K. Jannetty, Katina Calakos, William G. Janssen, Bruce S. McEwen, and John H. Morrison (Vol. 111, No. 52, December 30, 2014, p. 18733–18738).
Comments Off on CAAR – Proceedings of the National Academy of Sciences Article Abstracts – December 30, 2014
October 14, 2014
CAAR – Proceedings of the National Academy of Sciences Article Abstract – October 14, 2014
A. “Tissue injury and hypoxia promote malignant progression of prostate cancer by inducing CXCL13 expression in tumor myofibroblasts,” by Massimo Ammirante, Shabnam Shalapour, Youngjin Kang, Christina A. M. Jamieson, and Michael Karin (Vol. 111, No. 41, October 14, 2014, p. 14776-14781).
www.pnas.org/content/111/41/14776.abstract
B. “Modulation of age-related insulin sensitivity by VEGF-dependent vascular plasticity in adipose tissues,” by Jennifer Honek, Takahiro Seki, Hideki Iwamoto, Carina Fischer, Jingrong Li, Sharon Lim, Nilesh J. Samani, Jingwu Zang, and Yihai Cao (Vol. 111, No. 41, October 14, 2014, p. 14906-14911).
www.pnas.org/content/111/41/14906.abstract
C. “Vitamin D prevents cognitive decline and enhances hippocampal synaptic function in aging rats,” by Caitlin S. Latimer, Lawrence D. Brewer, James L. Searcy, Kuey-Chu Chen, Jelena Popovic, Susan D. Kraner, Olivier Thibault, Eric M. Blalock, Philip W. Landfield, and Nada M. Porter (Vol. 111, No. 41, October 14, 2014, p. E4359–E4366). Note: PNAS is providing open access to the full-text of this article.
www.pnas.org/content/111/41/E4359.abstract
D. “Proteopathic tau seeding predicts tauopathy in vivo,” by Brandon B. Holmes, Jennifer L. Furman, Thomas E. Mahan, Tritia R. Yamasaki, Hilda Mirbaha, William C. Eades, Larisa Belaygorod, Nigel J. Cairns, David M. Holtzman, and Marc I. Diamond (Vol. 111, No. 41, October 14, 2014, p. E4376–E4385).
Comments Off on CAAR – Proceedings of the National Academy of Sciences Article Abstract – October 14, 2014
May 15, 2014
CAAR – Public Library of Science (PLoS) Articles – May 15, 2014
A. “Consumption of Green Tea, but Not Black Tea or Coffee, Is Associated with Reduced Risk of Cognitive Decline,” by Moeko Noguchi-Shinohara, Sohshi Yuki, Chiaki Dohmoto, Yoshihisa Ikeda, Miharu Samuraki, Kazuo Iwasa, Masami Yokogawa, Kimiko Asai, Kiyonobu Komai, Hiroyuki Nakamura, and Masahito Yamada (PLoS ONE 9(5): e96013. doi:10.1371/journal.pone.0096013, HTML, XML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0096013
B. “Proteomics of Vitreous Humor of Patients with Exudative Age-Related Macular Degeneration,” by Michael Janusz Koss, Janosch Hoffmann, Nauke Nguyen, Marcel Pfister, Harald Mischak, William Mullen, Holger Husi, Robert Rejdak, Frank Koch, Joachim Jankowski, Katharina Krueger, Thomas Bertelmann, Julie Klein, Joost P. Schanstra, and Justyna Siwy (PLoS ONE 9(5): e96895. doi:10.1371/journal.pone.0096895, HTML, XML, and .pdf format, p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0096895
Comments Off on CAAR – Public Library of Science (PLoS) Articles – May 15, 2014
November 19, 2013
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – November 19, 2013
A. “Genetic basis of neurocognitive decline and reduced white-matter integrity in normal human brain aging,” by David C. Glahn, Jack W. Kent, Jr., Emma Sprooten, Vincent P. Diego, Anderson M. Winkler, Joanne E. Curran, D. Reese McKay, Emma E. Knowles, Melanie A Carless, Harald H. H. Goring, Thomas D. Dyer, Rene L. Olvera, Peter T. Fox, Laura Almasy, Jac Charlesworth, Peter Kochunov, Ravi Duggirala, and John Blangero (Vol. 110, No. 47, November 19, 2013, p. 19006-19011).
www.pnas.org/content/110/47/19006.abstract
B. “Regional variability of imaging biomarkers in autosomal dominant Alzheimer’s disease,” by Tammie L. S. Benzinger, Tyler Blazey, Clifford R. Jack, Jr., Robert A. Koeppe, Yi Su, Chengjie Xiong, Marcus E. Raichle, Abraham Z. Snyder, Beau M. Ances, Randall J. Bateman, Nigel J. Cairns, Anne M. Fagan, Alison Goate, Daniel S. Marcus, Paul S. Aisen, Jon J. Christensen, Lindsay Ercole, Russ C. Hornbeck, Angela M. Farrar, Patricia Aldea, Mateusz S. Jasielec, Christopher J. Owen, Xianyun Xie, Richard Mayeux, Adam Brickman, Eric McDade, William Klunk, Chester A. Mathis, John Ringman, Paul M. Thompson, Bernardino Ghetti, Andrew J. Saykin, Reisa A. Sperling, Keith A. Johnson, Stephen Salloway, Stephen Correia, Peter R. Schofield, Colin L. Masters, Christopher Rowe, Victor L. Villemagne, Ralph Martins, Sebastien Ourselin, Martin N. Rossor, Nick C. Fox, David M. Cash, Michael W. Weiner, David M. Holtzman, Virginia D. Buckles, Krista Moulder, and John C. Morris (Vol. 110, No. 47, November 19, 2013, p. E4502-E4509).
Comments Off on CAAR – Proceedings of the National Academy of Sciences Article Abstracts – November 19, 2013
September 3, 2013
CAAR – Public Library of Science (PLoS) Articles – September 3, 2013
A. “Cognitive Declines Precede and Predict Functional Declines in Aging and Alzheimer’s Disease,” by Laura B. Zahodne, Jennifer J. Manly, Anna MacKay-Brandt, and Yaakov Stern (PLoS ONE 8(9): e73645. doi:10.1371/journal.pone.0073645, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0073645
B. “Long-Term Effects of Statin Treatment in Elderly People: Extended Follow-Up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER),” by Suzanne M. Lloyd, David J. Stott, Anton J. M. de Craen, Patricia M. Kearney, Naveed Sattar, Ivan Perry, Christopher J. Packard, Andrew Briggs, Laura Marchbank, Harry Comber, J. Wouter Jukema, Rudi G. J. Westendorp, Stella Trompet, Brendan M. Buckley, and Ian Ford (PLoS ONE 8(9): e72642. doi:10.1371/journal.pone.0072642, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0072642
C. “Parkinson’s Disease Is Related to an Increased Risk of Ischemic Stroke-A Population-Based Propensity Score-Matched Follow-Up Study,” by Ya-Ping Huang, Li-Sheng Chen, Ming-Fang Yen, Ching-Yuan Fann, Yueh-Hsia Chiu, Hsiu-Hsi Chen, and Shin-Liang Pan (PLoS ONE 8(9): e68314. doi:10.1371/journal.pone.0068314, XML, HTML, and .pdf format, 6p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068314
D. “The Dopamine D3 Receptor Knockout Mouse Mimics Aging-Related Changes in Autonomic Function and Cardiac Fibrosis,” by Tracy L. Johnson, David A. Tulis, Benjamin E. Keeler, Jitka A. Virag, Robert M. Lust, and Stefan Clemens (PLoS ONE 8(8): e74116. doi:10.1371/journal.pone.0074116, XML, HTML, and .pdf format, 12p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0074116
Comments Off on CAAR – Public Library of Science (PLoS) Articles – September 3, 2013
June 14, 2013
CAAR – Public Library of Science (PLoS) Articles – June 14, 2013
A. “Diagnosed Mild Cognitive Impairment Due to Alzheimer’s Disease with PET Biomarkers of Beta Amyloid and Neuronal Dysfunction,” by Shizuo Hatashita and Hidetomo Yamasaki (PLoS ONE 8(6): e66877. doi:10.1371/journal.pone.0066877, XML, HTML, and .pdf format, 6p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0066877
B. “Evaluating Amyloid-{beta} Oligomers in Cerebrospinal Fluid as a Biomarker for Alzheimer’s Disease,” by Mikko Holtta, Oskar Hansson, Ulf Andreasson, Joakim Hertze, Lennart Minthon, Katarina Nagga, Niels Andreasen, Henrik Zetterberg, and Kaj Blennow (PLoS ONE 8(6): e66381. doi:10.1371/journal.pone.0066381, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0066381
C. “Risk Factors for Late-Life Cognitive Decline and Variation with Age and Sex in the Sydney Memory and Ageing Study,” by Darren M. Lipnicki, Perminder S. Sachdev, John Crawford, Simone Reppermund, Nicole A. Kochan, Julian N. Trollor, Brian Draper, Melissa J. Slavin, Kristan Kang, Ora Lux, Karen A. Mather, and Henry Brodaty (PLoS ONE 8(6): e65841. doi:10.1371/journal.pone.0065841, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0065841
Comments Off on CAAR – Public Library of Science (PLoS) Articles – June 14, 2013
April 8, 2013
CAAR – Institute for the Study of Labor (IZA) [University of Bonn, Germany] Working Papers – April 8, 2013
A. “Does Mental Productivity Decline with Age? Evidence from Chess Players,” by Marco Bertoni, Giorgio Brunello, and Lorenzo Rocco (Discussion Paper No. 7311, March 2013, .pdf format, 15p.). Note: Links to the abstract and full-text can be found at:
www.iza.org/en/webcontent/publications/papers/viewAbstract?dp_id=7311
B. “Evidence on Individual Preferences for Longevity Risk,” by Gaetan Delprat, Marie-Louise Leroux, and Pierre-Carl Michaud (Discussion Paper No. 7317, March 2013, .pdf format, 19p.). Note: Links to the abstract and full-text can be found at:
www.iza.org/en/webcontent/publications/papers/viewAbstract?dp_id=7317
Comments Off on CAAR – Institute for the Study of Labor (IZA) [University of Bonn, Germany] Working Papers – April 8, 2013
March 26, 2013
CAAR – Nature Neuroscience Article Abstracts – March 26, 2013
A. “Interplay of LRRK2 with chaperone-mediated autophagy,” by Samantha J. Orenstein, Sheng-Han Kuo, Inmaculada Tasset, Esperanza Arias, Hiroshi Koga, Irene Fernandez-Carasa, Etty Cortes, Lawrence S Honig, William Dauer, Antonella Consiglio, Angel Raya, David Sulzer and Ana Maria Cuervo (Vol. 16, No. 4, April 2013, p. 394-406).
www.nature.com/neuro/journal/v16/n4/abs/nn.3350.html
B. “Low hippocampal PI(4,5)P2 contributes to reduced cognition in old mice as a result of loss of MARCKS,” by Laura Trovo, Tariq Ahmed, Zsuzsanna Callaerts-Vegh, Andrea Buzzi, Claudia Bagni, Marinee Chuah, Thierry VandenDriessche, Rudi D’Hooge, Detlef Balschun and Carlos G. Dotti (Vol. 16, No. 4, April 2013, p. 449-455).
Comments Off on CAAR – Nature Neuroscience Article Abstracts – March 26, 2013
March 12, 2013
CAAR – Public Library of Science (PLoS) Articles – March 12, 2013
A. “Subclinical Thyroid Dysfunction and Cognitive Decline in Old Age,” by Liselotte W. Wijsman, Anton J. M. de Craen, Stella Trompet, Jacobijn Gussekloo, David J. Stott, Nicolas Rodondi, Paul Welsh, J. Wouter Jukema, Rudi G. J. Westendorp, and Simon P. Mooijaart (PLoS ONE 8(3): e59199. doi:10.1371/journal.pone.0059199, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059199
B. “PINCH in the Cellular Stress Response to Tau-Hyperphosphorylation,” by Ahmet Yunus Ozdemir, Inna Rom, Jane Kovalevich, William Yen, Radhika Adiga, Rajnish S. Dave, and Dianne Langford (PLoS ONE 8(3): e58232. doi:10.1371/journal.pone.0058232, XML, HTML, and .pdf format, 11p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058232
C. “Single-Subject Grey Matter Graphs in Alzheimer’s Disease,” by Betty M. Tijms, Christiane Moller, Hugo Vrenken, Alle Meije Wink, Willem de Haan, Wiesje M. van der Flier, Cornelis J. Stam, Philip Scheltens, and Frederik Barkhof (PLoS ONE 8(3): e58921. doi:10.1371/journal.pone.0058921, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058921
D. “United States Acculturation and Cancer Patients’ End-of-Life Care,” by Alexi A. Wright, Heather Stieglitz, Yankel M. Kupersztoch, M. Elizabeth Paulk, Yookyung Kim, Ingrid T. Katz, Francisco Munoz, Rachel B. Jimenez, Jan Mutchler, Lorna Rivera, Anthony L. Back, and Holly G. Prigerson (PLoS ONE 8(3): e58663. doi:10.1371/journal.pone.0058663, XML, HTML, and .pdf format, 10p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058663
E. “Force Control Deficits in Individuals with Parkinson’s Disease, Multiple Systems Atrophy, and Progressive Supranuclear,” by Palsy Kristina A. Neely, Peggy J. Planetta, Janey Prodoehl, Daniel M. Corcos, Cynthia L. Comella, Christopher G. Goetz, Kathleen L. Shannon, and David E. Vaillancourt (PLoS ONE 8(3): e58403. doi:10.1371/journal.pone.0058403, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058403
Comments Off on CAAR – Public Library of Science (PLoS) Articles – March 12, 2013
February 25, 2013
CAAR – Nature Neuroscience Article Abstract – February 25, 2013
“Prefrontal atrophy, disrupted NREM slow waves and impaired hippocampal-dependent memory in aging,” by Bryce A. Mander, Vikram Rao, Brandon Lu, Jared M. Saletin, John R. Lindquist, Sonia Ancoli-Israel, William Jagust & Matthew P. Walker (Vol. 16, No. 3, March 2013, p. 357-364).
Comments Off on CAAR – Nature Neuroscience Article Abstract – February 25, 2013
September 25, 2012
CAAR – Public Library of Science (PLoS) Articles – September 25, 2012
A. “Mild Cognitive Impairment Predicts Institutionalization among Older Men: A Population-Based Cohort Study,” by Danijela Gnjidic, Fiona F. Stanaway, Robert Cumming, Louise Waite, Fiona Blyth, Vasi Naganathan, David J. Handelsman, and David G. Le Couteur (PLoS ONE 7(9): e46061. doi:10.1371/journal.pone.0046061, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0046061
B. “Unveiling Clusters of RNA Transcript Pairs Associated with Markers of Alzheimer’s Disease Progression,” by Ahmed Shamsul Arefin, Luke Mathieson, Daniel Johnstone, Regina Berretta, and Pablo Moscato (PLoS ONE 7(9): e45535. doi:10.1371/journal.pone.0045535, XML, HTML, and .pdf format, 25p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0045535
Comments Off on CAAR – Public Library of Science (PLoS) Articles – September 25, 2012
September 7, 2012
CAAR – British Medical Journal Article – September 7, 2012
“Migraine and cognitive decline among women: prospective cohort study,” by Pamela M. Rist, Jae H. Kang, Julie E. Buring, M. Maria Glymour, Fran Grodstein, and Tobias Kurth (BMJ 2012;345:e5027, HTML and .pdf format).
Comments Off on CAAR – British Medical Journal Article – September 7, 2012
July 26, 2012
CAAR – Nature Neuroscience Brief Communication Abstract – July 26, 2012
“Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities,” by Ana M. M. Oliveira, Thekla J. Hemstedt and Hilmar Bading (Vol. 15, No. 8, August 2012, p. 1111-1113).
Comments Off on CAAR – Nature Neuroscience Brief Communication Abstract – July 26, 2012
July 23, 2012
CAAR – Public Library of Science (PLoS) Articles – July 23, 2012
A. “Enhanced Keratinocyte Proliferation and Migration in Co-culture with Fibroblasts,” by Zhenxiang Wang, Ying Wang, Farhang Farhangfar, Monica Zimmer, and Yongxin Zhang (PLoS ONE 7(7): e40951. doi:10.1371/journal.pone.0040951, XML, HTML, and .pdf format, 12p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0040951
B. “Use of Motor Abundance in Young and Older Adults during Dual-Task Treadmill Walking,” by Leslie M. Decker, Fabien Cignetti, Jane F. Potter, Stephanie A. Studenski, and Nicholas Stergiou (PLoS ONE 7(7): e41306. doi:10.1371/journal.pone.0041306, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0041306
C. “Association Study of Candidate Gene Polymorphisms with Amnestic Mild Cognitive Impairment in a Chinese Population,” by Xiaoyan Liu, Chunxian Yue, Zhi Xu, Hao Shu, Mengjia Pu, Hui Yu, Yongmei Shi, Liying Zhuang, Xiaohui Xu, and Zhijun Zhang (PLoS ONE 7(7): e41198. doi:10.1371/journal.pone.0041198, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0041198
Comments Off on CAAR – Public Library of Science (PLoS) Articles – July 23, 2012
July 5, 2012
CAAR – Public Library of Science (PLoS) Articles – July 5, 2012
A. “25-Hydroxyvitamin D Depletion Does Not Exacerbate MPTP-Induced Dopamine Neuron Damage in Mice,” by E. Danielle Dean, Lydia M. Mexas, Natalie L. Capiro, Jeanne E. McKeon, Mahlon R. DeLong, Kurt D. Pennell, Jonathan A. Doorn, Vin Tangpricha, Gary W. Miller, and Marian L. Evatt (PLoS ONE 7(7): e39227. doi:10.1371/journal.pone.0039227, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0039227
B. “Plasma BDNF Levels Vary in Relation to Body Weight in Females,” by Anilkumar Pillai, Davide Bruno, Antero S. Sarreal, Raymundo T. Hernando, Leslie A. Saint-Louis, Jay Nierenberg, Stephen D. Ginsberg, Nunzio Pomara, Pankaj D. Mehta, Henrik Zetterberg, Kaj Blennow, and Peter F. Buckley (PLoS ONE 7(7): e39358. doi:10.1371/journal.pone.0039358, XML, HTML, and .pdf format, 6p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0039358
C. “Executive Function and Falls in Older Adults: New Findings from a Five-Year Prospective Study Link Fall Risk to Cognition,” by Anat Mirelman, Talia Herman, Marina Brozgol, Moran Dorfman, Elliot Sprecher, Avraham Schweiger, Nir Giladi, and Jeffrey M. Hausdorff (PLoS ONE 7(6): e40297. doi:10.1371/journal.pone.0040297, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0040297
D. “Sexual Dimorphism in Healthy Aging and Mild Cognitive Impairment: A DTI Study,” by Laurence O’Dwyer, Franck Lamberton, Arun L. W. Bokde, Michael Ewers, Yetunde O. Faluyi, Colby Tanner, Bernard Mazoyer, Desmond O’Neill, Mairead Bartley, Ronan Collins, Tara Coughlan, David Prvulovic, and Harald Hampel (PLoS ONE 7(7): e37021. doi:10.1371/journal.pone.0037021, XML, HTML, and .pdf format, 12p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0037021
Comments Off on CAAR – Public Library of Science (PLoS) Articles – July 5, 2012
January 26, 2012
CAAR – British Medical Journal Articles – January 26, 2012
Note: these articles are available free of charge.
A. “Timing of onset of cognitive decline: results from Whitehall II prospective cohort study,” by Archana Singh-Manoux, Mika Kivimaki, M. Maria Glymour, Alexis Elbaz, Claudine Berr, Klaus P. Ebmeier, Jane E. Ferrie, and Aline Dugravot (BMJ 2012;344:d7622, Vol. 344, No. 7840, Jan. 21, 2012, HTML and .pdf format, 8p.).
www.bmj.com/content/344/bmj.d7622
B. “Short term outcomes of prostate biopsy in men tested for cancer by prostate specific antigen: prospective evaluation within ProtecT study,” by Derek J. Rosario, J. Athene Lane, Chris Metcalfe, Jenny L. Donovan, Andy Doble, Louise Goodwin, Michael Davis, James W.F. Catto, Kerry Avery, David E. Neal, and Freddie C. Hamdy (BMJ 2012;344:d7894, Vol. 344, No. 7840, Jan. 21, 2012, HTML and .pdf format, 12p.).
Comments Off on CAAR – British Medical Journal Articles – January 26, 2012
