Note: Check with your organization’s library for availability. “Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes,” by Joel W. Blanchard, Michael Bula, Jose Davila-Velderrain, Leyla Anne Akay, Lena Zhu, Alexander Frank, Matheus B. Victor, Julia Maeve Bonner, Hansruedi Mathys, Yuan-Ta Lin, Tak Ko, David A. Bennett, Hugh P. Cam, Manolis Kellis & Li-Huei Tsai (Vol. 26, No. 7, July 2020, p. 952-963).
June 24, 2020
CAAR – Nature Medicine Article – June 24, 2020
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May 6, 2020
CAAR – Nature Article – May 6, 2020
Note: Check with your organization’s library for availability. “APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline,” by Axel Montagne, Daniel A. Nation, Abhay P. Sagare, Giuseppe Barisano, Melanie D. Sweeney, Ararat Chakhoyan, Maricarmen Pachicano, Elizabeth Joe, Amy R. Nelson, Lina M. D’Orazio, David P. Buennagel, Michael G. Harrington, Tammie L. S. Benzinger, Anne M. Fagan, John M. Ringman, Lon S. Schneider, John C. Morris, Eric M. Reiman, Richard J. Caselli, Helena C. Chui, Julia TCW, Yining Chen, Judy Pa, Peter S. Conti, Meng Law, Arthur W. Toga & Berislav V. Zlokovic (Vol. 581, No. 7806, May 7, 2020, p. 71-76).
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January 31, 2017
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – January 31, 2017
A. “Helical structure, stability, and dynamics in human apolipoprotein E3 and E4 by hydrogen exchange and mass spectrometry,” by Palaniappan S. Chetty, Leland Mayne, Sissel Lund-Katz, S. Walter Englander, and Michael C. Phillips (Vol. 114, No. 5, January 31, 2017, p. 968-973).
www.pnas.org/content/114/5/968.abstract.html?etoc
B. “Nrf2 mitigates LRRK2- and {alpha}-synuclein–induced neurodegeneration by modulating proteostasis,” by Gaia Skibinski, Vicky Hwang, Dale Michael Ando, Aaron Daub, Alicia K. Lee, Abinaya Ravisankar, Sara Modan, Mariel M. Finucane, Benjamin A. Shaby, and Steven Finkbeiner (Vol. 114, No. 5, January 31, 2017, p. 1165–1170).
www.pnas.org/content/114/5/1165.abstract.html?etoc
C. “{alpha}-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation,” by Seong Su Kang, Zhentao Zhang, Xia Liu, Fredric P. Manfredsson, Li He, P. Michael Iuvone, Xuebing Cao, Yi E. Sun, Lingjing Jin, and Keqiang Ye (Vol. 114, No. 5, January 31, 2017, p. 1183–1185).
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November 8, 2016
CAAR – Public Library of Science (PLoS) Article – November 8, 2016
“Differential Effects of apoE4 and Activation of ABCA1 on Brain and Plasma Lipoproteins,” by Anat Boehm-Cagan, Roni Bar, Dror Harats, Aviv Shaish, Hana Levkovitz, John K. Bielicki, Jan O. Johansson, and Daniel M. Michaelson (PLoS ONE 11(11): e0166195. doi:10.1371/journal.pone.0166195, XML, HTML, and .pdf format, 17p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0166195
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