“Changing the Trajectory of Alzheimer’s: Reducing Risk, Detecting Early Symptoms, and Improving Data,” a hearing held June 19, 2018 (witness statement available in .pdf format, video of the full hearing available at the site, running time 2 hours 5 minutes). Note: Hearing begins at the 12:39 mark.
June 19, 2018
CAAR – US Senate Special Committee on Aging Hearing Testimony – June 19, 2018
Comments Off on CAAR – US Senate Special Committee on Aging Hearing Testimony – June 19, 2018
June 7, 2018
CAAR – Tables of Contents – June 7, 2018
Alzheimer’s and Dementia (Vol. 14, No. 6, June 2018).
www.alzheimersanddementia.com/issue/S1552-5260(17)X0008-3
American Journal of Geriatric Psychiatry (Vol. 26, No. 6, June 2018).
Comments Off on CAAR – Tables of Contents – June 7, 2018
June 4, 2018
CAAR – Tables of Contents – June 4, 2018
Journal of Alzheimer’s Disease (Vol. 63, No. 4, 2018).
content.iospress.com/journals/journal-of-alzheimers-disease/63/4
Journal of Population Ageing (Vol. 11, No. 2, March 2018).
Comments Off on CAAR – Tables of Contents – June 4, 2018
May 11, 2018
CAAR – Nature Medicine Letter Abstract – May 11, 2018
“PM20D1 is a quantitative trait locus associated with Alzheimer’s disease,” by Jose V. Sanchez-Mut, Holger Heyn, Bianca A. Silva, Lucie Dixsaut, Paula Garcia-Esparcia, Enrique Vidal, Sergi Sayols, Liliane Glauser, Ana Monteagudo-Sanchez, Jordi Perez-Tur, Isidre Ferrer, David Monk, Bernard Schneider, Manel Esteller & Johannes Graff (Vol. 24, No. 5, May 2018, p. 598-603).
Comments Off on CAAR – Nature Medicine Letter Abstract – May 11, 2018
May 9, 2018
May 7, 2018
CAAR – Tables of Contents – May 7, 2018
Alzheimer’s and Dementia: The Journal of the Alzheimer’s Association (Vol. 14, No. 5, May 2018).
www.alzheimersanddementia.com/issue/S1552-5260(17)X0007-1
American Journal of Geriatric Psychiatry (Vol. 26, No. 5, May 2018).
www.ajgponline.org/issue/S1064-7481(18)X0005-0
Clinical Gerontologist (Vol. 41, No. 4, 2018).
www.tandfonline.com/toc/wcli20/41/4?nav=tocList&
Journal of Aging Studies (Vol. 45, June 2018).
www.sciencedirect.com/journal/journal-of-aging-studies/vol/45/suppl/C
Journal of Applied Gerontology (Vol. 37, No. 6, June 2018).
Comments Off on CAAR – Tables of Contents – May 7, 2018
May 3, 2018
CAAR – New England Journal of Medicine Article – May 3, 2018
“Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer’s Disease,” by Michael F. Egan, James Kost, Pierre N. Tariot, Paul S. Aisen, Jeffrey L. Cummings, Bruno Vellas, Cyrille Sur, Yuki Mukai, Tiffini Voss, Christine Furtek, Erin Mahoney, Lyn Harper Mozley, Rik Vandenberghe, Yi Mo, and David Michelson (Vol. 378, No. 18, May 3, 2018, p. 1691-1703).
Comments Off on CAAR – New England Journal of Medicine Article – May 3, 2018
May 1, 2018
CAAR – Tables of Contents – May 1, 2018
Gerontechnology (Vol. 17, Suppl., April 2018).
journal.gerontechnology.org/pastIssuesList.aspx?iid=112
Journal of Alzheimer’s Disease (Vol. 63, No. 2, 2018).
content.iospress.com/journals/journal-of-alzheimers-disease/63/2
Journal of the American Geriatric Society (Vol. 66, No. 4, April 2018).
academic.oup.com/biomedgerontology/issue/73/5
Journal of Gerontological Social Work (Vol. 61, No. 4, 2018).
www.tandfonline.com/toc/wger20/61/4?nav=tocList
Journals of Gerontology (A): Biological Sciences (Vol. 73A, No. 5, May 2018).
Comments Off on CAAR – Tables of Contents – May 1, 2018
April 27, 2018
CAAR – Tables of Contents – April 27, 2018
Age and Ageing (Vol. 47, No. 3, May 2018).
academic.oup.com/ageing/issue/47/3
Ageing and Society (Vol. 38, No. 5, May 2018).
www.cambridge.org/core/journals/ageing-and-society/issue/1C99D2CE88D7D85073E77919454F26B5
American Journal of Alzheimer’s Disease & Other Dementias (Vol. 33, No. 4, June 2018).
journals.sagepub.com/toc/ajae/33/4
Canadian Journal on Aging / La Revue canadienne du vieillissement (Vol. 37, No. 2, June 2018).
Dementia (Vol. 17, No. 4, May 2018).
journals.sagepub.com/toc/dema/17/4
International Psychogeriatrics (Vol. 30, Nos. 2 & 3, February/March 2018).
No. 2, February 2018:
No. 3, March 2018:
Comments Off on CAAR – Tables of Contents – April 27, 2018
April 23, 2018
CAAR – Lancet Neurology Article Abstract – April 23, 2018
“The effect of APOE and other common genetic variants on the onset of Alzheimer’s disease and dementia: a community-based cohort study,” by Sven J. van der Lee, Frank J. Wolters, M. Kamran Ikram, Albert Hofman, M. Arfan Ikram, Najaf Amin, and Cornelia M. van Duijn (Vol. 17, No. 5, May 2018, p. 434-444).
www.thelancet.com/journals/laneur/article/PIIS1474-4422(18)30053-X/abstract
Comments Off on CAAR – Lancet Neurology Article Abstract – April 23, 2018
CAAR – Nature Article Abstract – April 23, 2018
“Innate immune memory in the brain shapes neurological disease hallmarks,” by Ann-Christin Wendeln, Karoline Degenhardt, Lalit Kaurani, Michael Gertig, Thomas Ulas, Gaurav Jain, Jessica Wagner, Lisa M. Hasler, Katleen Wild, Angelos Skodras, Thomas Blank, Ori Staszewski, Moumita Datta, Tonatiuh Pena Centeno, Vincenzo Capece, Md. Rezaul Islam, Cemil Kerimoglu, Matthias Staufenbiel, Joachim L. Schultze, Marc Beyer, Marco Prinz, Mathias Jucker, André Fischer & Jonas J. Neher (Vol. 556, No. 7701, April 19, 2018, p. 332-338).
Comments Off on CAAR – Nature Article Abstract – April 23, 2018
April 17, 2018
CAAR – Proceedings of the National Academies of Sciences Article Abstract – April 17, 2018
“Characterizing the human hippocampus in aging and Alzheimer’s disease using a computational atlas derived from ex vivo MRI and histology,” by Daniel H. Adler, Laura E. M. Wisse, Ranjit Ittyerah, John B. Pluta, Song-Lin Ding, Long Xie, Jiancong Wang, Salmon Kadivar, John L. Robinson, Theresa Schuck, John Q. Trojanowski, Murray Grossman, John A. Detre, Mark A. Elliott, Jon B. Toledo, Weixia Liu, Stephen Pickup, Michael I. Miller, Sandhitsu R. Das, David A. Wolk, and Paul A. Yushkevich (Vol. 115, No. 16, April 17, 2018, p. 4252-4257).
Comments Off on CAAR – Proceedings of the National Academies of Sciences Article Abstract – April 17, 2018
April 12, 2018
CAAR – Public Library of Science (PLoS) Articles – April 12, 2018
A. “Memory deficiency, cerebral amyloid angiopathy, and amyloid-{beta} plaques in APP+PS1 double transgenic rat model of Alzheimer’s disease,” by Diana Klakotskaia, Cansu Agca, Rachel A. Richardson, Edward G. Stopa, Todd R. Schachtman, and Yuksel Agca (PLoS ONE 13(4): e0195469. doi.org/10.1371/journal.pone.0195469, XML, HTML, and .pdf format, 16p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0195469
B. “Inflammatory markers in postoperative delirium (POD) and cognitive dysfunction (POCD): A meta-analysis of observational studies,” by Xuling Liu, Yang Yu, and Shengmei Zhu (PLoS ONE 13(4): e0195659. doi.org/10.1371/journal.pone.0195659, XML, HTML, and .pdf format, p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0195659
Comments Off on CAAR – Public Library of Science (PLoS) Articles – April 12, 2018
CAAR – Tables of Contents – April 12, 2018
Alzheimer’s and Dementia (Vol. 14, No. 4, April 2018).
www.alzheimersanddementia.com/issue/S1552-5260(17)X0006-X
Clinical Gerontologist (Vol. 41, No. 3, 2018).
www.tandfonline.com/toc/wcli20/41/3?nav=tocList&
Dementia (Vol. 17, No. 3, April 2018).
Comments Off on CAAR – Tables of Contents – April 12, 2018
April 10, 2018
CAAR – Proceedings of the National Academies of Science Article Abstract – April 10, 2018
“BACE1 SUMOylation increases its stability and escalates the protease activity in Alzheimer’s disease,” by Jian Bao, Min Qin, Yacoubou Abdoul Razak Mahaman, Bin Zhang, Fang Huang, Kuan Zeng, Yiyuan Xia, Dan Ke, Qun Wang, Rong Liu, Jian-Zhi Wang, Keqiang Ye, and Xiaochuan Wang (Vol. 115, No. 15, April 10, 2018, p. 3954-3959).
Comments Off on CAAR – Proceedings of the National Academies of Science Article Abstract – April 10, 2018
April 5, 2018
CAAR – Nature Neuroscience Article Abstract – April 5, 2018
“Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease,” by Raffaella Nativio, Greg Donahue, Amit Berson, Yemin Lan, Alexandre Amlie-Wolf, Ferit Tuzer, Jon B. Toledo, Sager J. Gosai, Brian D. Gregory, Claudio Torres, John Q. Trojanowski, Li-San Wang, F. Brad Johnson, Nancy M. Bonini & Shelley L. Berger (Vol. 21, No. 4, April 2018, p. 497-505).
Comments Off on CAAR – Nature Neuroscience Article Abstract – April 5, 2018
CAAR – Table of Contents – April 5, 2018
Journal of Alzheimer’s Disease (Vol. 62, No. 4, 2018).
content.iospress.com/journals/journal-of-alzheimers-disease/62/4
Comments Off on CAAR – Table of Contents – April 5, 2018
April 3, 2018
CAAR – Alzheimer’s Association Report – April 3, 2018
“2018 Alzheimer’s Disease Facts and Figures,” (March 2018, .pdf format, 85p.).
Comments Off on CAAR – Alzheimer’s Association Report – April 3, 2018
CAAR – Tables of Contents – April 3, 2018
American Journal of Alzheimer’s Disease & Other Dementias (Vol. 33, No. 3, May 2018).
journals.sagepub.com/toc/ajae/33/3
Journal of Gerontological Social Work (Vol. 61, No. 3, 2018).
Comments Off on CAAR – Tables of Contents – April 3, 2018
April 2, 2018
CAAR – Nature Neuroscience Article Abstract – April 2, 2018
“Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals,” by Heidi I. L. Jacobs, Trey Hedden, Aaron P. Schultz, Jorge Sepulcre, Rodrigo D. Perea, Rebecca E. Amariglio, Kathryn V. Papp, Dorene M. Rentz, Reisa A. Sperling & Keith A. Johnson (Vol. 21, No. 3, March 2018, p. 424-431).
Comments Off on CAAR – Nature Neuroscience Article Abstract – April 2, 2018
March 22, 2018
CAAR – Tables of Contents – March 22, 2018
Age and Ageing (Vol. 47, Suppl. 1, March 2018).
academic.oup.com/ageing/issue/47/suppl_1
Alzheimer’s and Dementia: Journal of the Alzheimer’s Association (Vol. 14, No. 3, March 2018).
www.alzheimersanddementia.com/issue/S1552-5260(17)X0005-8
Gerontologist (Vol. 58, No. 2, April 2018).
Comments Off on CAAR – Tables of Contents – March 22, 2018
March 20, 2018
CAAR – Proceedings of the National Academy of Science Article Abstracts – March 20, 2018
A. “Susceptibility of brain atrophy to TRIB3 in Alzheimer’s disease, evidence from functional prioritization in imaging genetics,” by Marco Lorenzi, Andre Altmann, Boris Gutman, Selina Wray, Charles Arber, Derrek P. Hibar, Neda Jahanshad, Jonathan M. Schott, Daniel C. Alexander, Paul M. Thompson, Sebastien Ourselin, and for the Alzheimer’s Disease Neuroimaging Initiative (Vol. 115, No. 12, March 20, 2018, p. 3162-3167).
www.pnas.org/content/115/12/3162?etoc=
B. “Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay,” by Andrew D. Nguyen, Thi A. Nguyen, Jiasheng Zhang, Swathi Devireddy, Ping Zhou, Anna M. Karydas, Xialian Xu, Bruce L. Miller, Frank Rigo, Shawn M. Ferguson, Eric J. Huang, Tobias C. Walther, and Robert V. Farese Jr. (Vol. 115, No. 12, March 20, 2018, p. E2849-E2858).
Comments Off on CAAR – Proceedings of the National Academy of Science Article Abstracts – March 20, 2018
March 19, 2018
CAAR – Tables of Contents – March 19, 2018
Ageing International (Vol. 43, No. 1, March 2018).
link.springer.com/journal/12126/43/1/page/1
American Journal of Geriatric Psychiatry (Vol. 26, No. 4, April 2018).
www.ajgponline.org/issue/S1064-7481(18)X0003-7
Journal of Alzheimer’s Disease (Vol. 62, No. 3, 2018).
content.iospress.com/journals/journal-of-alzheimers-disease/62/3
Journals of Gerontology (A): Biological Sciences (Vol. 73A, No. 4, April 2018).
Comments Off on CAAR – Tables of Contents – March 19, 2018
March 12, 2018
CAAR – Tables of Contents – March 12, 2018
International Journal of Aging and Human Development (Vol. 86, No. 3, April 2018).
journals.sagepub.com/toc/ahdb/86/3
Journal of Alzheimer’s Disease (Vol. 62, No. 2, 2018).
content.iospress.com/journals/journal-of-alzheimers-disease/62/2
Journal of Cross-Cultural Gerontology (Vol. 33, No. 1, March 2018).
link.springer.com/journal/10823/33/1/page/1
Journal of Pension Economics (Vol. 17, No. 2, April 2018).
Research on Aging (Vol. 40, No. 4, April 2018).
Comments Off on CAAR – Tables of Contents – March 12, 2018
March 6, 2018
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – March 6, 2018
A. “Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice,” by Kan Xie, Devon P. Ryan, Brandon L. Pearson, Kristin S. Henzel, Frauke Neff, Ramon O. Vidal, Magali Hennion, Isabelle Lehmann, Melvin Schleif, Susanne Schröder, Thure Adler, Birgit Rathkolb, Jan Rozman, Anna-Lena Schütz, Cornelia Prehn, Michel E. Mickael, Marco Weiergräber, Jerzy Adamski, Dirk H. Busch, Gerhard Ehninger, Anna Matynia, Walker S. Jackson, Eckhard Wolf, Helmut Fuchs, Valerie Gailus-Durner, Stefan Bonn, Martin Hrabe de Angelis and Dan Ehninger (Vol. 115, No. 10, March 6, 2018, p. E2348-E2357).
doi.org/10.1073/pnas.1707337115
B. “Environmental enrichment and exercise are better than social enrichment to reduce memory deficits in amyloid beta neurotoxicity,” by Mariza G. Prado Lima, Helen L. Schimidt, Alexandre Garcia, Letícia R. Daré, Felipe P. Carpes, Ivan Izquierdo and Pâmela B. Mello-Carpes (Vol. 115, No. 10, March 6, 2018, p. E2403-E2408).
Comments Off on CAAR – Proceedings of the National Academy of Sciences Article Abstracts – March 6, 2018
February 26, 2018
CAAR – Public Library of Science (PLoS) Articles – February 26, 2018
A. “Social capital and Internet use in an age-comparative perspective with a focus on later life,” by Barbara Barbosa Neves, Jaime R. S. Fonseca, Fausto Amaro, and Adriano Pasqualotti (PLoS ONE 13(2): e0192119. doi.org/10.1371/journal.pone.0192119, XML, HTML, and .pdf format, 27p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0192119
B. “Analysis of age-related changes in psychosine metabolism in the human brain,” by Michael S. Marshall, Benas Jakubauskas, Wil Bogue, Monika Stoskute, Zane Hauck, Emily Rue, Matthew Nichols, Lisa L. DiAntonio, Richard B. van Breemen, Jeffrey H. Kordower, Carlos A. Saavedra-Matiz, and Ernesto R. Bongarzone (PLoS ONE 13(2): e0193438. doi.org/10.1371/journal.pone.0193438, XML, HTML, and .pdf format, 20p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0193438
Comments Off on CAAR – Public Library of Science (PLoS) Articles – February 26, 2018
February 20, 2018
CAAR – Proceedings of the National Academies of Sciences Article Abstracts – February 20, 2018
A. “Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence,” by Yang Zhao, Alexander Tyshkovskiy, Daniel Muñoz-Espín, Xiao Tian, Manuel Serrano, Joao Pedro de Magalhaes, Eviatar Nevo, Vadim N. Gladyshev, Andrei Seluanov and Vera Gorbunova (Vol. 115, No. 8, February 20, 2018, p. 1801-1806).
www.pnas.org/content/115/8/1801
B. “NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency,” by Yujun Hou, Sofie Lautrup, Stephanie Cordonnier, Yue Wang, Deborah L. Croteau, Eduardo Zavala, Yongqing Zhang, Kanako Moritoh, Jennifer F. O’Connell, Beverly A. Baptiste, Tinna V. Stevnsner, Mark P. Mattson and Vilhelm A. Bohr (Vol. 115, No. 8, February 20, 2018, p. E1876-E1885).
www.pnas.org/content/115/8/E1876
C. “Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis,” by Xiaopu Zhou, Yu Chen, Kin Y. Mok, Qianhua Zhao, Keliang Chen, Yuewen Chen, John Hardy, Yun Li, Amy K. Y. Fu, Qihao Guo, Nancy Y. Ip and for the Alzheimer’s Disease Neuroimaging Initiative (Vol. 115, No. 8, February 20, 2018, p. 1697-1706)
Comments Off on CAAR – Proceedings of the National Academies of Sciences Article Abstracts – February 20, 2018
February 12, 2018
CAAR – Public Library of Science (PLoS) Article – February 12, 2018
“Evaluation of inner retinal layers as biomarkers in mild cognitive impairment to moderate Alzheimer’s disease,” by Eleonora M. Lad, Dibyendu Mukherjee, Sandra S. Stinnett, Scott W. Cousins, Guy G. Potter, James R. Burke, Sina Farsiu, and Heather E. Whitson (PLoS ONE 13(2): e0192646. doi.org/10.1371/journal.pone.0192646, XML, HTML, and .pdf format, 15p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0192646
Comments Off on CAAR – Public Library of Science (PLoS) Article – February 12, 2018
February 8, 2018
CAAR – Nature Letter Abstract – February 8, 2018
“High performance plasma amyloid-{beta} biomarkers for Alzheimer’s disease,” by Akinori Nakamura, Naoki Kaneko, Victor L. Villemagne, Takashi Kato, James Doecke, Vincent Doré, Chris Fowler, Qiao-Xin Li, Ralph Martins, Christopher Rowe, Taisuke Tomita, Katsumi Matsuzaki, Kenji Ishii, Kazunari Ishii, Yutaka Arahata, Shinichi Iwamoto, Kengo Ito, Koichi Tanaka, Colin L. Masters & Katsuhiko Yanagisawa (Vol. 554, No. , February 8, 2018, p. 249-254).
Comments Off on CAAR – Nature Letter Abstract – February 8, 2018
February 7, 2018
CAAR – Proceedings of the National Academy of Science Article Abstracts – February 7, 2018
A. “Intracellular Ca2+ stores control in vivo neuronal hyperactivity in a mouse model of Alzheimer’s disease,” by Chommanad Lerdkrai, Nithi Asavapanumas, Bianca Brawek, Yury Kovalchuk, Nima Mojtahedi, Maria Olmedillas del Moral and Olga Garaschuk (Vol. 115, No. 6, February 6, 2018, p. E1279-E1288).
www.pnas.org/content/115/6/E1279
B. “Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer’s disease,” by Rachel E. Bennett, Ashley B. Robbins, Miwei Hu, Xinrui Cao, Rebecca A. Betensky, Tim Clark, Sudeshna Das and Bradley T. Hyman (Vol. 115, No. 6, February 6, 2018, .pdf and HTML format, p. E1289-E1298). Note: PNAS is providing open access to the full-text of this article.
Comments Off on CAAR – Proceedings of the National Academy of Science Article Abstracts – February 7, 2018
CAAR – Table of Contents – February 7, 2018
Journal of Alzheimer’s Disease (Vol. 62, No. 1, 2018).
content.iospress.com/journals/journal-of-alzheimers-disease/62/1
Comments Off on CAAR – Table of Contents – February 7, 2018
February 6, 2018
CAAR – Public Library of Science (PLoS) Articles – February 6, 2018
A. “A mathematical model of multisite phosphorylation of tau protein,” by Alexander Stepanov, Tatiana Karelina, Nikolai Markevich, Oleg Demin, and Timothy Nicholas (PLoS ONE 13(2): e0192519. doi.org/10.1371/journal.pone.0192519, XML, HTML, and .pdf format, 17p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0192519
B. “Computational modelling of pathogenic protein spread in neurodegenerative diseases,” by Konstantinos Georgiadis, Selina Wray, Sébastien Ourselin, Jason D. Warren, and Marc Modat (PLoS ONE 13(2): e0192518. doi.org/10.1371/journal.pone.0192518, XML, HTML, and .pdf format, 15p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0192518
Comments Off on CAAR – Public Library of Science (PLoS) Articles – February 6, 2018
February 5, 2018
CAAR – Tables of Contents – February 5, 2018
Alzheimer’s and Dementia: The Journal of the Alzheimer’s Association (Vol. 14, No. 2, February 2018).
www.alzheimersanddementia.com/issue/S1552-5260(17)X0004-6
Dementia (Vol. 17, No. 2, February 2018).
journals.sagepub.com/toc/dema/17/2
Gerontologist (Vol. 58, No. 1, February 2018).
academic.oup.com/gerontologist/issue/58/1
Research on Aging (Vol. 40, No. 3, March 2018).
Comments Off on CAAR – Tables of Contents – February 5, 2018
January 29, 2018
CAAR – New England Journal of Medicine Article Abstract – January 29, 2018
“Trial of Solanezumab for Mild Dementia Due to Alzheimer’s Disease,” by Lawrence S. Honig, Bruno Vellas, Michael Woodward, Mercè Boada, Roger Bullock, Michael Borrie, Klaus Hager, Niels Andreasen, Elio Scarpini, Hong Liu-Seifert, Michael Case, Robert A. Dean, Ann Hake, Karen Sundell, Vicki Poole Hoffmann, Christopher Carlson, Rashna Khanna, Mark Mintun, Ronald DeMattos, Katherine J. Selzler, and Eric Siemers (Vol. 378, No. 4, January 25, 2018, p. 321-330).
Comments Off on CAAR – New England Journal of Medicine Article Abstract – January 29, 2018
January 25, 2018
CAAR – Table of Contents – January 25, 2018
Journal of Alzheimer’s Disease (Vol. 61, No. 4, 2018).
content.iospress.com/journals/journal-of-alzheimers-disease/61/4
Comments Off on CAAR – Table of Contents – January 25, 2018
January 24, 2018
CAAR – Table of Contents – January 24, 2018
American Journal of Alzheimer’s Disease & Other Dementias (Vol. 33, No. 2, March 2018).
Comments Off on CAAR – Table of Contents – January 24, 2018
January 23, 2018
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – January 23, 2018
A. “Structural heterogeneity and intersubject variability of A{beta} in familial and sporadic Alzheimer’s disease,” by Carlo Condello, Thomas Lemmin, Jan Stöhr, Mimi Nick, Yibing Wu, Alison M. Maxwell, Joel C. Watts, Christoffer D. Caro, Abby Oehler, C. Dirk Keene, Thomas D. Bird, Sjoerd G. van Duinen, Lars Lannfelt, Martin Ingelsson, Caroline Graff, Kurt Giles, William F. DeGrado, and Stanley B. Prusiner (Vol. 115, No. 4, January 23, 2018, .pdf and HTML format, p. E782-E791). Note: PNAS is providing open access to the full-text of this article.
www.pnas.org/content/115/4/E782.abstract
B. “GBA1 deficiency negatively affects physiological {alpha}-synuclein tetramers and related multimers,” by Sangjune Kim, Seung Pil Yun, Saebom Lee, George Essien Umanah, Veera Venkata Ratnam Bandaru, Xiling Yin, Peter Rhee, Senthilkumar S. Karuppagounder, Seung-Hwan Kwon, Hojae Lee, Xiaobo Mao, Donghoon Kim, Akhilesh Pandey, Gabsang Lee, Valina L. Dawson, Ted M. Dawson, and Han Seok Ko (Vol. 115, No. 4, January 23, 2018, p. 798-803).
www.pnas.org/content/115/4/798.abstract
C. “CFH and ARMS2 genetic risk determines progression to neovascular age-related macular degeneration after antioxidant and zinc supplementation,” by Demetrios G. Vavvas, Kent W. Small, Carl C. Awh, Brent W. Zanke, Robert J. Tibshirani, and Rafal Kustra (Vol. 115, No. 4, January 23, 2018, .pdf and HTML format, p. E696-E704). Note: PNAS is providing open access to the full-text of this article.
Comments Off on CAAR – Proceedings of the National Academy of Sciences Article Abstracts – January 23, 2018
January 18, 2018
CAAR – Proceedings of the National Academy of Sciences Article Abstracts – January 18, 2018
A. “The prodrug of 7,8-dihydroxyflavone development and therapeutic efficacy for treating Alzheimer’s disease,” by Chun Chen, Zhihao Wang, Zhentao Zhang, Xia Liu, Seong Su Kang, Ying Zhang, and Keqiang Ye (Vol. 115, No. 3, January 16, 2018, p. 578-583).
www.pnas.org/content/115/3/578.abstract
B. “Migration-based selections of antibodies that convert bone marrow into trafficking microglia-like cells that reduce brain amyloid {beta},” by Kyung Ho Han, Britni M. Arlian, Matthew S. Macauley, James C. Paulson, and Richard A. Lerner (Vol. 115, No. 3, January 16, 2018, p. E372-E381). Note: PNAS is providing open-access to the full-text of this article.
Comments Off on CAAR – Proceedings of the National Academy of Sciences Article Abstracts – January 18, 2018
CAAR – Lancet Neurology Article Abstracts – January 18, 2018
A. “Accelerated long-term forgetting in presymptomatic autosomal dominant Alzheimer’s disease: a cross-sectional study,” by Philip S. J. Weston, Jennifer M. Nicholas, Susie M. D. Henley, Yuying Liang, Kirsty Macpherson, Elizabeth Donnachie, Jonathan M. Schott, Martin N. Rossor, Sebastian J. Crutch, Christopher R. Butler, Adam Z. Zeman, and Nick C. Fox (Vol. 17, No. 2, February 2018, p. 123-132).
www.thelancet.com/journals/laneur/article/PIIS1474-4422(17)30434-9/abstract
B. “Effectiveness and costs of specialised physiotherapy given via ParkinsonNet: a retrospective analysis of medical claims data,” by Jan H. L. Ypinga, Nienke M. de Vries, Lieke H. H. M. Boonen, Xander Koolman, Marten Munneke, Aeilko H. Zwinderman, and Bastiaan R. Bloem (Vol. 17, No. 2, February 2018, p. 153-161).
www.thelancet.com/journals/laneur/article/PIIS1474-4422(17)30406-4/abstract
Comments Off on CAAR – Lancet Neurology Article Abstracts – January 18, 2018
January 11, 2018
CAAR – Tables of Contents – January 11, 2018
Journal of Alzheimer’s Disease (Vol. 61, No. 3, 2018).
content.iospress.com/journals/journal-of-alzheimers-disease/61/3
Journals of Gerontology (B): Psychological Sciences (Vol. 73B, No. 2, March 2018).
academic.oup.com/psychsocgerontology/issue/73/2
Journal of Pension Economics and Finance (Vol. 17, No. 1, January 2018).
Comments Off on CAAR – Tables of Contents – January 11, 2018
January 9, 2018
CAAR – Journal of the American Medical Association Article – January 9, 2018
Note: The link below is to the table of contents for the current issue of JAMA (Vol. 319, No. 2, January 2, 2018). Check with your organization’s information center for availability.
jamanetwork.com/journals/jama/issue/319/2
“Effect of Idalopirdine as Adjunct to Cholinesterase Inhibitors on Change in Cognition in Patients With Alzheimer Disease: Three Randomized Clinical Trials,” by Alireza Atri, Lutz Frolich, Clive Ballard, Pierre N. Tariot, Jose Luis Molinuevo, Neli Boneva, Kristian Windfeld, Lars L. Raket, and Jeffrey L. Cummings (p. 130-142).
Comments Off on CAAR – Journal of the American Medical Association Article – January 9, 2018
CAAR – Nature Medicine Article Abstracts – January 9, 2018
A. “Amyloid-{beta} plaques enhance Alzheimer’s brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation,” by Zhuohao He, Jing L. Guo, Jennifer D. McBride, Sneha Narasimhan, Hyesung Kim, Lakshmi Changolkar, Bin Zhang, Ronald J. Gathagan, Cuiyong Yue, Christopher Dengler, Anna Stieber, Magdalena Nitla, Douglas A. Coulter, Ted Abel, Kurt R. Brunden, John Q. Trojanowski & Virginia M-Y Lee (Vol. 24, No. 1, January 2018, p. 29-38).
www.nature.com/articles/nm.4443
B. “cGAS drives noncanonical-inflammasome activation in age-related macular degeneration,” by Nagaraj Kerur, Shinichi Fukuda, Daipayan Banerjee, Younghee Kim, Dongxu Fu, Ivana Apicella, Akhil Varshney, Reo Yasuma, Benjamin J. Fowler, Elmira Baghdasaryan, Kenneth M. Marion, Xiwen Huang, Tetsuhiro Yasuma, Yoshio Hirano, Vlad Serbulea, Meenakshi Ambati, Vidya L. Ambati, Yuji Kajiwara, Kameshwari Ambati, Shuichiro Hirahara, Ana Bastos-Carvalho, Yuichiro Ogura, Hiroko Terasaki, Tetsuro Oshika, Kyung Bo Kim, David R. Hinton, Norbert Leitinger, John C. Cambier, Joseph D.Buxbaum, M. Cristina Kenney, S. Michal Jazwinski, Hiroshi Nagai, Isao Hara, A. Phillip West, Katherine A. Fitzgerald, SriniVas R. Sadda, Bradley D. Gelfand & Jayakrishna Ambati (Vol. 24, No. 1, January 2018, p. 50-61).
Comments Off on CAAR – Nature Medicine Article Abstracts – January 9, 2018
January 5, 2018
CAAR – Tables of Contents – January 5, 2017
Journal of Aging Studies (Vol. 43, 2017).
www.sciencedirect.com/journal/journal-of-aging-studies/vol/43/suppl/C
Journal of Alzheimer’s Disease (Vol. 61, No. 2, 2017).
content.iospress.com/journals/journal-of-alzheimers-disease/61/2
Comments Off on CAAR – Tables of Contents – January 5, 2017
January 4, 2018
CAAR – Nature Neuroscience Article Abstract – January 4, 2017
“Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo,” by Daniel J. Apicco, Peter E. A. Ash, Brandon Maziuk, Chelsey LeBlang, Maria Medalla, Ali Al Abdullatif, Antonio Ferragud, Emily Botelho, Heather I. Ballance, Uma Dhawan, Samantha Boudeau, Anna Lourdes Cruz, Daniel Kashy, Aria Wong, Lisa R. Goldberg, Neema Yazdani, Cheng Zhang, Choong Y. Ung, Yorghos Tripodis, Nicholas M. Kanaan, Tsuneya Ikezu, Pietro Cottone, John Leszyk, Hu Li, Jennifer Luebke, Camron D. Bryant & Benjamin Wolozin (Vol. 21, No. 1, January 2018, p. 72-80).
Comments Off on CAAR – Nature Neuroscience Article Abstract – January 4, 2017
January 2, 2018
December 22, 2017
CAAR – Proceedings of the National Academies of Science Article Abstracts – December 22, 2017
A. “Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice,” by Noah R. Johnson, Carlo Condello, Shenheng Guan, Abby Oehler, Julia Becker, Marta Gavidia, George A. Carlson, Kurt Giles, and Stanley B. Prusiner (Vol. 114, No. 51, December 19, 2017, p. E11029-E11036).
www.pnas.org/content/114/51/E11029.abstract
B. “Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1,” by D. Cristopher Bragg, Kotchaphorn Mangkalaphiban, Christine A. Vaine, Nichita J. Kulkarni, David Shin, Rachita Yadav, Jyotsna Dhakal, Mai-Linh Ton, Anne Cheng, Christopher T. Russo, Mark Ang, Patrick Acuña, Criscely Go, Taylor N. Franceour, Trisha Multhaupt-Buell, Naoto Ito, Ulrich Müller, William T. Hendriks, Xandra O. Breakefield, Nutan Sharma, and Laurie J. Ozelius (Vol. 114, No. 51, December 19, 2017, p. E11020-E11028). Note: _PNAS_ is providing open access to the full-text of this article.
Comments Off on CAAR – Proceedings of the National Academies of Science Article Abstracts – December 22, 2017
December 14, 2017
CAAR – Nature Article Abstract – December 14, 2017
“Enhancing mitochondrial proteostasis reduces amyloid-{beta} proteotoxicity,” by Vincenzo Sorrentino, Mario Romani, Laurent Mouchiroud, John S. Beck, Hongbo Zhang, Davide D’Amico, Norman Moullan, Francesca Potenza, Adrien W. Schmid, Solene Rietsch, Scott E. Counts & Johan Auwerx (Vol. 552, No. 7684, December 14, 2017, p. 187-193).
www.nature.com/nature/journal/v552/n7684/abs/nature25143.html
Comments Off on CAAR – Nature Article Abstract – December 14, 2017
December 11, 2017
CAAR – Tables of Contents – December 11, 2017
Alzheimer’s and Dementia: Journal of the Alzheimer’s Association (Vol. 13, No. 12, December 2017).
www.alzheimersanddementia.com/issue/S1552-5260(16)X0025-8
American Journal of Geriatric Psychiatry (Vol. 26, No. 1, January 2018).
www.ajgponline.org/issue/S1064-7481(16)X0015-2
Journal of Applied Gerontology (Vol. 37, No. 1, January 2018).
journals.sagepub.com/toc/jaga/37/1
Journal of Elder Abuse & Neglect (Vol. 30, No. 1, 2018).
Comments Off on CAAR – Tables of Contents – December 11, 2017
December 7, 2017
CAAR – Proceedings of the National Academies of Science Article Abstracts – December 7, 2017
A. “Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease,” by Jay Rasmussen, Jasmin Mahler, Natalie Beschorner, Stephan A. Kaeser, Lisa M. Häsler, Frank Baumann, Sofie Nyström, Erik Portelius, Kaj Blennow, Tammaryn Lashley, Nick C. Fox, Diego Sepulveda-Falla, Markus Glatzel, Adrian L. Oblak, Bernardino Ghetti, K. Peter R. Nilsson, Per Hammarström, Matthias Staufenbiel, Lary C. Walker, and Mathias Jucker (Vol. 114, No. 49, December 5, 2017, p. 13018-13023).
B. “Intercellular competition and the inevitability of multicellular aging,” by Paul Nelson and Joanna Masel (Vol. 114, No. 49, December 5, 2017, p. 12982–12987).
Comments Off on CAAR – Proceedings of the National Academies of Science Article Abstracts – December 7, 2017
November 30, 2017
CAAR – Public Library of Science (PLoS) Articles – November 30, 2017
A. “Assemblies of amyloid-{beta}<sub>30–36</sub> hexamer and its G33V/L34T mutants by replica-exchange molecular dynamics simulation,” by Zhenyu Qian, Qingwen Zhang, Yu Liu, and Peijie Chen (PLoS ONE 12(11): e0188794. doi.org/10.1371/journal.pone.0188794, XML, HTML, and .pdf format, 18p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0188794
B. “Elderly emergency patients presenting with non-specific complaints: Characteristics and outcomes,” by Joyce J. H. Wachelder, Patricia M. Stassen, Laura P. A. M. Hubens, Steffie H. A. Brouns, Suze L. E. Lambooij, Jeanne P. Dieleman, and Harm R. Haak (PLoS ONE 12(11): e0188954. doi.org/10.1371/journal.pone.0188954, XML, HTML, and .pdf format, 11p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0188954
C. “Identifying social factors amongst older individuals in linked electronic health records: An assessment in a population based study,” by Anu Jain, Albert J. van Hoek, Jemma L. Walker, Rohini Mathur, Liam Smeeth, and Sara L. Thomas (PLoS ONE 12(11): e0189038. doi.org/10.1371/journal.pone.0189038, XML, HTML, and .pdf format, 17p.).
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0189038
Comments Off on CAAR – Public Library of Science (PLoS) Articles – November 30, 2017
