CDHA CAAR

February 19, 2020

CAAR – Proceedings of the National Academy of Science Article – February 19, 2020

Note: Check with your organization’s library for availability. “The {alpha}-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure,” by David R. Boyer, Binsen Li, Chuanqi Sun, Weijia Fan, Kang Zhou, Michael P. Hughes, Michael R. Sawaya, Lin Jiang, and David S. Eisenberg (Vol. 117, No. 7, February 18, 2020, p. 3592-3602).

www.pnas.org/content/117/7/3592

January 21, 2020

CAAR – Proceedings of the National Academy of Sciences Article – January 21, 2020

Note: Check with your organization’s library for availability. “NK cells clear {alpha}-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse model of {alpha}-synucleinopathy,” by Rachael H. Earls, Kelly B. Menees, Jaegwon Chung, Claire-Anne Gutekunst, Hyun Joon Lee, Manuel G. Hazim, Balázs Rada, Levi B. Wood, and Jae-Kyung Lee (Vol. 117, No. 3, January 21, 2020, p. 1762-1771).

www.pnas.org/content/117/3/1762

January 6, 2020

CAAR – Nature Neuroscience Article – January 6, 2020

Filed under: Reports and Articles — Tags: — admin @ 4:38 pm

Note: Check with your organization’s library for availability. “{alpha}-Synuclein strains target distinct brain regions and cell types,” by Angus Lau, Raphaella W. L. So, Heather H. C. Lau, Jason C. Sang, Alejandro Ruiz-Riquelme, Shelaine C. Fleck, Erica Stuart, Sindhu Menon, Naomi P. Visanji, Georg Meisl, Rania Faidi, Maria M. Marano, Cian Schmitt-Ulms, Zhilan Wang, Paul E. Fraser, Anurag Tandon, Bradley T. Hyman, Holger Wille, Martin Ingelsson, David Klenerman & Joel C. Watts (Vol. 23, No. 1, January 2020, p. 21-31).

www.nature.com/articles/s41593-019-0541-x

CAAR – Nature Article – January 6, 2020

Filed under: Reports and Articles — Tags: , — admin @ 4:37 pm

Note: Check with your organization’s library for availability. “Regulation of {alpha}-synuclein by chaperones in mammalian cells,” by Björn M. Burmann, Juan A. Gerez, Irena Matecko-Burmann, Silvia Campioni, Pratibha Kumari, Dhiman Ghosh, Adam Mazur, Emelie E. Aspholm, Darius Šulskis, Magdalena Wawrzyniuk, Thomas Bock, Alexander Schmidt, Stefan G. D. Rüdiger, Roland Riek & Sebastian Hiller (Vol. 577, No. 7788, January 2, 2020, p. 127-132).

www.nature.com/articles/s41586-019-1808-9

October 8, 2019

CAAR – Proceedings of the National Academy of Sciences Article Abstracts – October 8, 2019

A. “Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence,” by Cristian Tomasetti, Justin Poling, Nicholas J. Roberts, Nyall R. London Jr., Meredith E. Pittman, Michael C. Haffner, Anthony Rizzo, Alex Baras, Baktiar Karim, Antonio Kim, Christopher M. Heaphy, Alan K. Meeker, Ralph H. Hruban, Christine A. Iacobuzio-Donahue, and Bert Vogelstein (Vol. 116, No. 41, October 8, 2019, p. 20482-20488).

www.pnas.org/content/116/41/20482

B. “Parkinson’s disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and {alpha}-synuclein stability through membrane remodeling,” by Akio Mori, Taku Hatano, Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Takahiro Koinuma, Hongrui Meng, Shin-ichiro Kubo, Spencer Spratt, Changxu Cui, Chikara Yamashita, Yoshimi Miki, Kei Yamamoto, Tetsuya Hirabayashi, Makoto Murakami, Yoshikazu Takahashi, Hideo Shindou, Takashi Nonaka, Masato Hasegawa, Ayami Okuzumi, Yuzuru Imai, and Nobutaka Hattori (Vol. 116, No. 41, October 8, 2019, p. 20689-20699).

www.pnas.org/content/116/41/20689

September 5, 2019

CAAR – Proceedings of the National Academies of Science Article Abstract – September 5, 2019

Filed under: Reports and Articles — Tags: , — admin @ 5:43 pm

Parkinson’s disease is a type of amyloidosis featuring accumulation of amyloid fibrils of {alpha}-synuclein,” by Katsuya Araki, Naoto Yagi, Koki Aoyama, Chi-Jing Choong, Hideki Hayakawa, Harutoshi Fujimura, Yoshitaka Nagai, Yuji Goto, and Hideki Mochizuki (Vol. 116, No. 36, September 3, 2019, p. 17963-17969).

www.pnas.org/content/116/36/17963

July 30, 2019

CAAR – Nature Neuroscience Article Abstracts – July 30, 2019

Filed under: Reports and Articles — Tags: , , — admin @ 5:30 pm

A. “Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer’s disease pathogenesis,” by Pilar Esteve, Javier Rueda-Carrasco, María Inés Mateo, María Jesús Martin-Bermejo, Jonathan Draffin, Guadalupe Pereyra, África Sandonís, Inmaculada Crespo, Inmaculada Moreno, Ester Aso, Paula Garcia-Esparcia, Estrella Gomez-Tortosa, Alberto Rábano, Juan Fortea, Daniel Alcolea, Alberto Lleo, Michael T. Heneka, José M. Valpuesta, José A. Esteban, Isidro Ferrer, Mercedes Domínguez & Paola Bovolenta (Vol. 22, No. 8, August 2019, p. 1258-1268).

www.nature.com/articles/s41593-019-0432-1

B. “Spread of {alpha}-synuclein pathology through the brain connectome is modulated by selective vulnerability and predicted by network analysis,” by Michael X. Henderson, Eli J. Cornblath, Adam Darwich, Bin Zhang, Hannah Brown, Ronald J. Gathagan, Raizel M. Sandler, Danielle S. Bassett, John Q. Trojanowski & Virginia M. Y. Lee (Vol. 22, No. 8, August 2019, p. 1248-1257).

www.nature.com/articles/s41593-019-0457-5

July 23, 2019

CAAR – Proceedings of the National Academies of Science Article Abstract – July 23, 2019

Filed under: Reports and Articles — Tags: , — admin @ 5:43 pm

{alpha}-synuclein−lipoprotein interactions and elevated ApoE level in cerebrospinal fluid from Parkinson’s disease patients,” by Wojciech Paslawski, Justyna Zareba-Paslawska, Xiaoqun Zhang, Katharina Hölzl, Henrik Wadensten, Mohammadreza Shariatgorji, Shorena Janelidze, Oskar Hansson, Lars Forsgren, Per E. Andrén, and Per Svenningsson (Vol. 116, No. 30, July 23, 2019, p. 15226-15235).

www.pnas.org/content/116/30/15226

January 29, 2019

CAAR – Proceedings of the National Academies of Science Article Abstract – January 29, 2019

Filed under: Reports and Articles — Tags: , — admin @ 5:48 pm

{alpha}-Synuclein O-GlcNAcylation alters aggregation and toxicity, revealing certain residues as potential inhibitors of Parkinson’s disease,” by Paul M. Levine, Ana Galesic, Aaron T. Balana, Anne-Laure Mahul-Mellier, Mariana X. Navarro, Cesar A. De Leon, Hilal A. Lashuel, and Matthew R. Pratt (Vol. 116, No. 5, January 29, 2019, p. 1511-1519).

www.pnas.org/content/116/5/1511

November 5, 2018

CAAR – Science Article Abstract – November 5, 2018

Filed under: Reports and Articles — Tags: , , — admin @ 3:06 pm

Poly(ADP-ribose) drives pathologic {alpha}-synuclein neurodegeneration in Parkinson’s disease,” by Tae-In Kam, Xiaobo Mao, Hyejin Park, Shih-Ching Chou, Senthilkumar S. Karuppagounder, George Essien Umanah, Seung Pil Yun, Saurav Brahmachari, Nikhil Panicker, Rong Chen, Shaida A. Andrabi, Chen Qi, Guy G. Poirier, Olga Pletnikova, Juan C. Troncoso, Lynn M. Bekris, James B. Leverenz, Alexander Pantelyat, Han Seok Ko, Liana S. Rosenthal, Ted M. Dawson, Valina L. Dawson (Vol. 362, No. 6414, November 2, 2018).

science.sciencemag.org/content/362/6414/eaat8407

October 10, 2018

CAAR – Proceedings of the National Academy of Science Article Abstracts – October 10, 2018

A. “Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer’s disease,” by Sarah K. Baker, Zu-Lin Chen, Erin H. Norris, Alexey S. Revenko, A. Robert MacLeod, and Sidney Strickland (Vol. 115, No. 41, October 9, 2018, p. E9687-E9696).

www.pnas.org/content/115/41/E9687

B. “Small molecule inhibits a-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons,” by Jordi Pujols, Samuel Peña-Díaz, Diana F. Lázaro, Francesca Peccati, Francisca Pinheiro, Danilo González, Anita Carija, Susanna Navarro, María Conde-Giménez, Jesús García, Salvador Guardiola, Ernest Giralt, Xavier Salvatella, Javier Sancho, Mariona Sodupe, Tiago Fleming Outeiro, Esther Dalfó, and Salvador Ventura (Vol. 115, No. 41, October 9, 2018, p. 10481-10486).

www.pnas.org/content/115/41/10481

July 26, 2018

CAAR – Proceedings of the National Academy of Sciences Article Abstract – July 26, 2018

{alpha}-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies,” by Iryna Prots, Janina Grosch, Razvan-Marius Brazdis, Katrin Simmnacher, Vanesa Veber, Steven Havlicek, Christian Hannappel, Florian Krach, Mandy Krumbiegel, Oliver Schutz, Andre Reis, Wolfgang Wrasidlo, Douglas R. Galasko, Teja W. Groemer, Eliezer Masliah, Ursula Schlotzer-Schrehardt, Wei Xiang, Jürgen Winkler, and Beate Winner (Vol. 115, No. 30, July 24, 2018, p. 7813-7818).

www.pnas.org/content/115/30/7813

July 12, 2018

CAAR – Proceedings of the National Academy of Sciences Article Abstracts – July 12, 2018

A. “Identification and nanomechanical characterization of the fundamental single-strand protofilaments of amyloid {alpha}-synuclein fibrils,” by Francesco Simone Ruggeri, Fabrizio Benedetti, Tuomas P. J. Knowles, Hilal A. Lashuel, Sergey Sekatskii, and Giovanni Dietler (Vol. 115 No. 28, July 10, 2018, p. 7230-7235).

www.pnas.org/content/115/28/7230

B. “Declining mental health among disadvantaged Americans,” by Noreen Goldman, Dana A. Glei, and Maxine Weinstein (Vol. 115 No. 28, July 10, 2018, p. 7290-7295).

www.pnas.org/content/115/28/7290

C. “Amyloid clearance defect in ApoE4 astrocytes is reversed by epigenetic correction of endosomal pH,” by Hari Prasad and Rajini Rao (Vol. 115 No. 28, July 10, 2018, p. E6640-E6649).

www.pnas.org/content/115/28/E6640

May 24, 2018

CAAR – Nature Letter Abstract – May 24, 2018

Filed under: Reports and Articles — Tags: , , — admin @ 5:09 pm

Cellular milieu imparts distinct pathological {alpha}-synuclein strains in {alpha}-synucleinopathies,” by Chao Peng, Ronald J. Gathagan, Dustin J. Covell, Coraima Medellin, Anna Stieber, John L. Robinson, Bin Zhang, Rose M. Pitkin, Modupe F. Olufemi, Kelvin C. Luk, John Q. Trojanowski & Virginia M.-Y. Lee (Vol. 557, No. 7706, May 24, 2018, p. 558-563).

www.nature.com/articles/s41586-018-0104-4

March 14, 2018

CAAR – Proceedings of the National Academy of Sciences Article Abstract – March 14, 2018

Identification of a highly neurotoxic {alpha}-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease,” by Diego Grassi, Shannon Howard, Minghai Zhou, Natalia Diaz-Perez, Nicolai T. Urban, Debbie Guerrero-Given, Naomi Kamasawa, Laura A. Volpicelli-Daley, Philip LoGrasso, and Corinne Ida Lasmezas (Vol. 115, No. 11, March 13, 2018, p. E2634-E2643).

www.pnas.org/content/115/11/E2634?etoc=

February 13, 2018

CAAR – Proceedings of the National Academies of Science Article Abstract – February 13, 2018

Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice,” by Yulan Xiong, Stewart Neifert, Senthilkumar S. Karuppagounder, Qinfang Liu, Jeannette N. Stankowski, Byoung Dae Lee, Han Seok Ko, Yunjong Lee, Jonathan C. Grima, Xiaobo Mao, Haisong Jiang, Sung-Ung Kang, Deborah A. Swing, Lorraine Iacovitti, Lino Tessarollo, Ted M. Dawson, and Valina L. Dawson (Vol. 115, No. 7, February 13, 2018, p. 1635-1640).

www.pnas.org/content/115/7/1635

January 23, 2018

CAAR – Proceedings of the National Academy of Sciences Article Abstracts – January 23, 2018

A. “Structural heterogeneity and intersubject variability of A{beta} in familial and sporadic Alzheimer’s disease,” by Carlo Condello, Thomas Lemmin, Jan Stöhr, Mimi Nick, Yibing Wu, Alison M. Maxwell, Joel C. Watts, Christoffer D. Caro, Abby Oehler, C. Dirk Keene, Thomas D. Bird, Sjoerd G. van Duinen, Lars Lannfelt, Martin Ingelsson, Caroline Graff, Kurt Giles, William F. DeGrado, and Stanley B. Prusiner (Vol. 115, No. 4, January 23, 2018, .pdf and HTML format, p. E782-E791). Note: PNAS is providing open access to the full-text of this article.

www.pnas.org/content/115/4/E782.abstract

B. “GBA1 deficiency negatively affects physiological {alpha}-synuclein tetramers and related multimers,” by Sangjune Kim, Seung Pil Yun, Saebom Lee, George Essien Umanah, Veera Venkata Ratnam Bandaru, Xiling Yin, Peter Rhee, Senthilkumar S. Karuppagounder, Seung-Hwan Kwon, Hojae Lee, Xiaobo Mao, Donghoon Kim, Akhilesh Pandey, Gabsang Lee, Valina L. Dawson, Ted M. Dawson, and Han Seok Ko (Vol. 115, No. 4, January 23, 2018, p. 798-803).

www.pnas.org/content/115/4/798.abstract

C. “CFH and ARMS2 genetic risk determines progression to neovascular age-related macular degeneration after antioxidant and zinc supplementation,” by Demetrios G. Vavvas, Kent W. Small, Carl C. Awh, Brent W. Zanke, Robert J. Tibshirani, and Rafal Kustra (Vol. 115, No. 4, January 23, 2018, .pdf and HTML format, p. E696-E704). Note: PNAS is providing open access to the full-text of this article.

www.pnas.org/content/115/4/E696.abstract

January 9, 2018

CAAR – Proceedings of the National Academy of Sciences Article Abstract – January 9, 2018

Familial Parkinson’s point mutation abolishes multiple system atrophy prion replication,” by Amanda L. Woerman, Sabeen A. Kazmi, Smita Patel, Atsushi Aoyagi, Abby Oehler, Kartika Widjaja, Daniel A. Mordes, Steven H. Olson, and Stanley B. Prusiner (Vol. 115, No. 2, January 9, 2018, p. 409-414).

www.pnas.org/content/115/2/409.abstract

December 14, 2017

CAAR – Science Report Abstract – December 14, 2017

Filed under: Reports and Articles — Tags: , , — admin @ 4:49 pm

Structural basis of membrane disruption and cellular toxicity by {alpha}-synuclein oligomers,” by Giuliana Fusco, Serene W. Chen, Philip T. F. Williamson, Roberta Cascella, Michele Perni, James A. Jarvis, Cristina Cecchi, Michele Vendruscolo, Fabrizio Chiti, Nunilo Cremades5, Liming Ying, Christopher M. Dobson, and Alfonso De Simone (Vol. 358, No. 6369, December 15, 2017, p. 1440-1443).

science.sciencemag.org/content/358/6369/1440

October 31, 2017

CAAR – Nature Neuroscience Article Abstracts – October 31, 2017

Filed under: Reports and Articles — Tags: , , , — admin @ 4:44 pm

A. “[alpha]-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B,” by Diana G Ferreira, Mariana Temido-Ferreira, Hugo Vicente Miranda, Vania L. Batalha, Joana E. Coelho, Eva M. Szego, Ines Marques-Morgado, Sandra H. Vaz, Jeong Seop Rhee, Matthias Schmitz, Inga Zerr, Luísa V. Lopes & Tiago F. Outeiro (Vol. 20, No. 11, November 2017, p. 1569-1579).

www.nature.com/neuro/journal/v20/n11/abs/nn.4648.html

B. “Dopamine induces soluble {alpha}-synuclein oligomers and nigrostriatal degeneration,” by Danielle E. Mor, Elpida Tsika, Joseph R. Mazzulli, Neal S. Gould, Hanna Kim, Malcolm J. Daniels, Shachee Doshi, Preetika Gupta, Jennifer L. Grossman, Victor X. Tan, Robert G. Kalb, Kim A Caldwell, Guy A. Caldwell, John H. Wolfe & Harry Ischiropoulos (Vol. 20, No. 11, November 2017, p. 1560-1568).

www.nature.com/neuro/journal/v20/n11/abs/nn.4641.html

September 26, 2017

CAAR – Proceedings of the National Academy of Sciences Article Abstract – September 26, 2017

Modeling Parkinson’s disease pathology by combination of fibril seeds and {alpha}-synuclein overexpression in the rat brain,” by Poonam Thakur, Ludivine S. Breger, Martin Lundblad, Oi Wan Wan, Bengt Mattsson, Kelvin C. Luk, Virginia M. Y. Lee, John Q. Trojanowski, and Anders Bjorklund (Vol. 114, No. 39, September 26, 2017, p. E8284–E8293).

www.pnas.org/content/114/39/E8284.abstract.html?etoc

September 5, 2017

CAAR – Science Article Abstract – September 5, 2017

Filed under: Reports and Articles — Tags: , — admin @ 4:07 pm

{beta}2-Adrenoreceptor is a regulator of the {alpha}-synuclein gene driving risk of Parkinson’s disease,” by Shuchi Mittal, Kjetil Bjornevik, Doo Soon Im, Adrian Flierl, Xianjun Dong, Joseph J. Locascio, Kristine M. Abo, Elizabeth Long, Ming Jin, Bing Xu, Yang K. Xiang, Jean-Christophe Rochet, Anders Engeland, Patrizia Rizzu, Peter Heutink, Tim Bartels, Dennis J. Selkoe, Barbara J. Caldarone, Marcie A. Glicksman, Vikram Khurana, Birgitt Schule, David S. Park, Trond Riise, and Clemens R. Scherzer (Vol. 357, No. 6354, September 1, 2017, p. 891-898).

science.sciencemag.org/content/357/6354/891

June 28, 2017

CAAR – Nature Letter Abstract – June 28, 2017

Filed under: Reports and Articles — Tags: , , — admin @ 5:15 pm

T cells from patients with Parkinson’s disease recognize {alpha}-synuclein peptides,” by David Sulzer, Roy N. Alcalay, Francesca Garretti, Lucien Cote, Ellen Kanter, Julian Agin-Liebes, Christopher Liong, Curtis McMurtrey, William H. Hildebrand, Xiaobo Mao, Valina L. Dawson, Ted M. Dawson, Carla Oseroff, John Pham, John Sidney, Myles B. Dillon, Chelsea Carpenter, Daniela Weiskopf, Elizabeth Phillips, Simon Mallal, Bjoern Peters, April Frazier, Cecilia S. Lindestam Arlehamn & Alessandro Sette (Vol. 546, No. 7660, June 29, 2017, p. 656-661).

www.nature.com/nature/journal/v546/n7660/abs/nature22815.html

June 20, 2017

CAAR – Proceedings of the National Academy of Sciences Article Abstract – June 20, 2017

Treatment with diphenyl–pyrazole compound anle138b/c reveals that {alpha}-synuclein protects melanoma cells from autophagic cell death,” by Elisa Turriani, Diana F. Lazaro, Sergey Ryazanov, Andrei Leonov, Armin Giese, Margarete Schon, Michael P. Schon, Christian Griesinger, Tiago F. Outeiro, Donna J. Arndt-Jovin, and Dorothea Becker (Vol. 114, No. 25, June 21, 2017, p. E4971–E4977).

www.pnas.org/content/114/25/E4971.abstract.html?etoc

June 6, 2017

CAAR – Proceedings of the National Academy of Sciences Article Abstract – June 6, 2017

Selective lowering of synapsins induced by oligomeric {alpha}-synuclein exacerbates memory deficits,” by Megan E. Larson, Susan J. Greimel, Fatou Amar, Michael LaCroix, Gabriel Boyle, Mathew A. Sherman, Hallie Schley, Camille Miel, Julie A. Schneider, Rakez Kayed, Fabio Benfenati, Michael K. Lee, David A. Bennett, and Sylvain E. Lesne (Vol. 114, No. 23, June 7, 2017, p. E4648-E4657).

www.pnas.org/content/114/23/E4648.abstract

April 26, 2017

CAAR – Nature Neuroscience Article Abstract – April 26, 2017

Filed under: Reports and Articles — Tags: , , — admin @ 5:18 pm

{alpha}-Synuclein promotes dilation of the exocytotic fusion pore,” by Todd Logan, Jacob Bendor, Chantal Toupin, Kurt Thorn & Robert H. Edwards (Vol. 20, No. 5, May 2017, p. 681-689).

www.nature.com/neuro/journal/v20/n5/abs/nn.4529.html

February 28, 2017

CAAR – Proceedings of the National Academy of Sciences Article Abstract – February 28, 2017

TMEM175 deficiency impairs lysosomal and mitochondrial function and increases {alpha}-synuclein aggregation,” by Sarah Jinn, Robert E. Drolet, Paige E. Cramer, Andus Hon-Kit Wong, Dawn M. Toolan, Cheryl A. Gretzula, Bhavya Voleti, Galya Vassileva, Jyoti Disa, Marija Tadin-Strapps, and David J. Stone (Vol. 114, No. 9, February 28, 2017, .pdf and HTML format, p. 2389-2394). Note: PNAS is providing open access to the full-text of this article.

www.pnas.org/content/114/9/2389.abstract

February 10, 2017

CAAR – Public Library of Science (PLoS) Article – February 10, 2017

Filed under: Reports and Articles — Tags: , — admin @ 4:55 pm

{alpha}-Synuclein increases {beta}-amyloid secretion by promoting {beta}-/{gamma}-secretase processing of APP,” by Hazel L. Roberts, Bernard L. Schneider, and David R. Brown (PLoS ONE 12(2): e0171925. doi:10.1371/journal.pone.0171925, XML, HTML, and .pdf format, 22p.).

journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0171925

January 31, 2017

CAAR – Proceedings of the National Academy of Sciences Article Abstracts – January 31, 2017

A. “Helical structure, stability, and dynamics in human apolipoprotein E3 and E4 by hydrogen exchange and mass spectrometry,” by Palaniappan S. Chetty, Leland Mayne, Sissel Lund-Katz, S. Walter Englander, and Michael C. Phillips (Vol. 114, No. 5, January 31, 2017, p. 968-973).

www.pnas.org/content/114/5/968.abstract.html?etoc

B. “Nrf2 mitigates LRRK2- and {alpha}-synuclein–induced neurodegeneration by modulating proteostasis,” by Gaia Skibinski, Vicky Hwang, Dale Michael Ando, Aaron Daub, Alicia K. Lee, Abinaya Ravisankar, Sara Modan, Mariel M. Finucane, Benjamin A. Shaby, and Steven Finkbeiner (Vol. 114, No. 5, January 31, 2017, p. 1165–1170).

www.pnas.org/content/114/5/1165.abstract.html?etoc

C. “{alpha}-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation,” by Seong Su Kang, Zhentao Zhang, Xia Liu, Fredric P. Manfredsson, Li He, P. Michael Iuvone, Xuebing Cao, Yi E. Sun, Lingjing Jin, and Keqiang Ye (Vol. 114, No. 5, January 31, 2017, p. 1183–1185).

www.pnas.org/content/114/5/1183.abstract.html?etoc

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