CDHA CAAR

February 7, 2018

CAAR – Lancet Oncology Article Abstracts – February 7, 2018

Filed under: Reports and Articles — Tags: , — admin @ 3:15 pm

A. “Safety and preliminary efficacy of venetoclax with decitabine or azacitidine in elderly patients with previously untreated acute myeloid leukaemia: a non-randomised, open-label, phase 1b study,” by Courtney D. DiNardo, Keith W. Pratz, Anthony Letai, Brian A. Jonas, Andrew H. Wei, Michael Thirman, Martha Arellano, Mark G. Frattini, Hagop Kantarjian, Relja Popovic, Brenda Chyla, Tu Xu, Martin Dunbar, Suresh K. Agarwal, Rod Humerickhouse, Mack Mabry, Jalaja Potluri, Marina Konopleva, and Daniel A. Pollyea (Vol. 19, No. 2, February 2018, p. 216-228).

www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30010-X/abstract

B. “Inotuzumab ozogamicin in combination with low-intensity chemotherapy for older patients with Philadelphia chromosome-negative acute lymphoblastic leukaemia: a single-arm, phase 2 study,” by Hagop Kantarjian, Farhad Ravandi, Nicholas J. Short, Xuelin Huang, Nitin Jain, Koji Sasaki, Naval Daver, Naveen Pemmaraju, Joseph D. Khoury, Jeffrey Jorgensen, Yesid Alvarado, Marina Konopleva, Guillermo Garcia-Manero, Tapan Kadia, Musa Yilmaz, Gautam Bortakhur, Jan Burger, Steven Kornblau, William Wierda, Courtney DiNardo, Alessandra Ferrajoli, Jovitta Jacob, Rebecca Garris, Susan O’Brien, and Elias Jabbour (Vol. 19, No. 2, February 2018, p. 240-248).

www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30011-1/abstract

February 25, 2015

CAAR – Nature Letter Abstract – February 25, 2015

Filed under: Reports and Articles — Tags: , — admin @ 5:00 pm

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia,” by Terrence N. Wong, Giridharan Ramsingh, Andrew L. Young, Christopher A. Miller, Waseem Touma, John S. Welch, Tamara L. Lamprecht, Dong Shen, Jasreet Hundal, Robert S. Fulton, Sharon Heath, Jack D. Baty, Jeffery M. Klco, Li Ding, Elaine R. Mardis, Peter Westervelt, John F. DiPersio, Matthew J. Walter, Timothy A. Graubert, Timothy J. Ley, Todd E. Druley, Daniel C. Link & Richard K. Wilson (Vol. 518, No. 7540, February 26, 2015, p. 552-555).

www.nature.com/nature/journal/v518/n7540/abs/nature13968.html

July 22, 2014

CAAR – Proceedings of the National Academy of Sciences Article Abstracts – July 22, 2014

Filed under: Reports and Articles — Tags: , , , — admin @ 4:58 pm

A. “Allosteric regulation of {gamma}-secretase activity by a phenylimidazole-type {gamma}-secretase modulator,” by Koji Takeo, Shun Tanimura, Takehiro Shinoda, Satoko Osawa, Ivan Krasmirov Zahariev, Naoki Takegami, Yoshiko Ishizuka-Katsura, Naoko Shinya, Shizuka Takagi-Niidome, Aya Tominaga, Noboru Ohsawa, Tomomi Kimura-Someya, Mikako Shirouzu, Satoshi Yokoshima, Shigeyuki Yokoyama, Tohru Fukuyama, Taisuke Tomita, and Takeshi Iwatsubo (Vol. 111, No. 29, July 22, 2014, p. 10544-10549).

www.pnas.org/content/111/29/10544.abstract

B. “Tif1{gamma} regulates the TGF-{beta}1 receptor and promotes physiological aging of hematopoietic stem cells,” by Ronan Quere, Laetitia Saint-Paul, Virginie Carmignac, Romain Z. Martin, Marie-Lorraine Chretien, Anne Largeot, Arlette Hammann, Jean-Paul Pais de Barros, Jean-Noel Bastie, and Laurent Delva (Vol. 111, No. 29, July 22, 2014, p. 10592-10597).

www.pnas.org/content/111/29/10592.abstract

C. “Intramuscular injection of {alpha}-synuclein induces CNS {alpha}-synuclein pathology and a rapid-onset motor phenotype in transgenic mice,” by Amanda N. Sacino, Mieu Brooks, Michael A. Thomas, Alex B. McKinney, Sooyeon Lee, Robert W. Regenhardt, Nicholas H. McGarvey, Jacob I. Ayers, Lucia Notterpek, David R. Borchelt, Todd E. Golde, and Benoit I. Giasson (Vol. 111, No. 29, July 22, 2014, p. 10732-10737).

www.pnas.org/content/111/29/10732.abstract

April 8, 2013

CAAR – Lancet Oncology Article Abstract – April 8, 2013

Filed under: Reports and Articles — Tags: — admin @ 4:02 pm

Two dosing regimens of tosedostat in elderly patients with relapsed or refractory acute myeloid leukaemia (OPAL): a randomised open-label phase 2 study,” by Jorge Cortes, Eric Feldman, Karen Yee, David Rizzieri, Anjali S. Advani, Anthony Charman, Richard Spruyt, Martin Toal, and Hagop Kantarjian (Vol. 14, No. 4, April 2013, p. 354-362).

www.thelancet.com/journals/lanonc/article/PIIS1470-2045%2813%2970037-8/abstract

October 30, 2012

CAAR – Lancet Oncology Article Abstract – October 30, 2012

Filed under: Reports and Articles — Tags: — admin @ 4:13 pm

Note: Lancet requires free registration prior to providing content. “Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study,” by Hagop Kantarjian, Stefan Faderl, Guillermo Garcia-Manero, Selina Luger, Parameswaran Venugopal, Lori Maness, Meir Wetzler, Steven Coutre, Wendy Stock, David Claxton, Stuart L Goldberg, Martha Arellano, Stephen A Strickland, Karen Seiter, Gary Schiller, Elias Jabbour, Judy Chiao, and William Plunkett (Vol. 13, No. 11, November 2012, p. 1096-1104).

www.thelancet.com/journals/lanonc/article/PIIS1470-2045%2812%2970436-9/abstract

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