A. “M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer’s disease genes and improving memory,” by Claude-Henry Volmar, Hasib Salah-Uddin, Karolina J. Janczura, Paul Halley, Guerline Lambert, Andrew Wodrich, Sivan Manoah, Nidhi H. Patel, Gregory C. Sartor, Neil Mehta, Nancy T. H. Miles, Sachi Desse, David Dorcius, Michael D. Cameron, Shaun P. Brothers, and Claes Wahlestedt (Vol. 114, No. 43, October 24, 2017, .pdf and HTML format, p. E9135–E9144). Note: PNAS is providing open access to the full text of this article.
www.pnas.org/content/114/43/E9135.abstract
B. “TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy,” by Cheryl E. G. Leyns, Jason D. Ulrich, Mary B. Finn, Floy R. Stewart, Lauren J. Koscal, Javier Remolina Serrano, Grace O. Robinson, Elise Anderson, Marco Colonna, and David M. Holtzman (Vol. 114, No. 43, October 24, 2017, .pdf and HTML format, p. 11524-11529). Note: PNAS is providing open access to the full text of this article.