February 7, 2018

CAAR – US Senate Special Committee on Aging Hearing Testimony – February 7, 2018

Filed under: Legislation Information Updates — Tags: — admin @ 3:18 pm

From Joint Pain to Pocket Pain: Cost and Competition Among Rheumatoid Arthritis Therapies,” a hearing held February 7, 2018 (witness statements available in .pdf format, video of the full hearing available at the site, running time 1 hour 35 minutes). Note: The hearing begins at the 15:30 mark.

CAAR – Proceedings of the National Academy of Science Article Abstracts – February 7, 2018

Filed under: Reports and Articles — Tags: , — admin @ 3:17 pm

A. “Intracellular Ca2+ stores control in vivo neuronal hyperactivity in a mouse model of Alzheimer’s disease,” by Chommanad Lerdkrai, Nithi Asavapanumas, Bianca Brawek, Yury Kovalchuk, Nima Mojtahedi, Maria Olmedillas del Moral and Olga Garaschuk (Vol. 115, No. 6, February 6, 2018, p. E1279-E1288).

B. “Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer’s disease,” by Rachel E. Bennett, Ashley B. Robbins, Miwei Hu, Xinrui Cao, Rebecca A. Betensky, Tim Clark, Sudeshna Das and Bradley T. Hyman (Vol. 115, No. 6, February 6, 2018, .pdf and HTML format, p. E1289-E1298). Note: PNAS is providing open access to the full-text of this article.

CAAR – Lancet Oncology Article Abstracts – February 7, 2018

Filed under: Reports and Articles — Tags: , — admin @ 3:15 pm

A. “Safety and preliminary efficacy of venetoclax with decitabine or azacitidine in elderly patients with previously untreated acute myeloid leukaemia: a non-randomised, open-label, phase 1b study,” by Courtney D. DiNardo, Keith W. Pratz, Anthony Letai, Brian A. Jonas, Andrew H. Wei, Michael Thirman, Martha Arellano, Mark G. Frattini, Hagop Kantarjian, Relja Popovic, Brenda Chyla, Tu Xu, Martin Dunbar, Suresh K. Agarwal, Rod Humerickhouse, Mack Mabry, Jalaja Potluri, Marina Konopleva, and Daniel A. Pollyea (Vol. 19, No. 2, February 2018, p. 216-228).

B. “Inotuzumab ozogamicin in combination with low-intensity chemotherapy for older patients with Philadelphia chromosome-negative acute lymphoblastic leukaemia: a single-arm, phase 2 study,” by Hagop Kantarjian, Farhad Ravandi, Nicholas J. Short, Xuelin Huang, Nitin Jain, Koji Sasaki, Naval Daver, Naveen Pemmaraju, Joseph D. Khoury, Jeffrey Jorgensen, Yesid Alvarado, Marina Konopleva, Guillermo Garcia-Manero, Tapan Kadia, Musa Yilmaz, Gautam Bortakhur, Jan Burger, Steven Kornblau, William Wierda, Courtney DiNardo, Alessandra Ferrajoli, Jovitta Jacob, Rebecca Garris, Susan O’Brien, and Elias Jabbour (Vol. 19, No. 2, February 2018, p. 240-248).

CAAR – International Longevity Centre [UK] Report – February 7, 2018

Filed under: Reports and Articles — Tags: — admin @ 3:12 pm

Stronger Foundations – International Lessons for the Housing-with-Care Sector in the UK,” by Brian Beach (January 2018, .pdf format, 24p.).

CAAR – Table of Contents – February 7, 2018

Filed under: Journal Table of Contents — Tags: — admin @ 3:10 pm

Journal of Alzheimer’s Disease (Vol. 62, No. 1, 2018).

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