Current Awareness in Aging Research (CAAR) Report #621 -- January 12, 2012

CAAR (Current Awareness in Aging Research) is a weekly email report produced by the Center for Demography of Health and Aging at the University of Wisconsin-Madison that helps researchers keep up to date with the latest developments in the field. For more information, including an archive of back issues and subscription information see:


NOTE: The CAAR weblog will be available beginning next Thursday, January 19, 2012. The message you receive from us next Thursday will be an announcement of the weblog and contain instructions on how best to use it. Relevant Internet addresses will be provided at that time.


I. Data:

1. HUMAN MORTALITY DATABASE: Note: HMD requires free registration before providing data. The following updates have been added to the database:

Data for Austria were revised and updated through 2010 (1/9/2012).

Data for Iceland were revised and updated through 2010 (1/6/2012).

Data availability:

Data access:


II. Reports and articles:

2. US CONGRESSIONAL BUDGET OFFICE BRIEF: "Raising the Ages of Eligibility for Medicare and Social Security," (January 2012, .pdf format, 12p.).


3. US GOVERNMENT ACCOUNTABILITY OFFICE REPORT: "Medicare Advantage: Changes Improved Accuracy of Risk Adjustment for Certain Beneficiaries," (GAO-12-52, December 2011, .pdf format, 39p.).


4. US DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF INSPECTOR GENERAL REPORT: "Hospital Incident Reporting Systems Do Not Capture Most Patient Harm," (OEI-06-09-00091, January 2012, .pdf format, 35p.).


5. US CENTERS FOR MEDICARE AND MEDICAID SERVICES DATA BRIEF: "Flu shots and the characteristics of unvaccinated elderly Medicare beneficiaries," by Kimberly A. Lochner and Marc Wynne (Q4, 2011, .pdf format, 11p.).


6. US ADMINISTRATION ON AGING NEWSLETTER: AoA eNewsletter (Jan. 9, 2012, .pdf format, 8p.).


7. UK DEPARTMENT OF WORK AND PENSIONS REPORT: "Attitudes to age in Britain 2010/11," by Daniel Sweiry and Maxine Willitts (In-House Research No. 7, January 2012, .pdf format, 108p.).


8. UK PARLIAMENT BRIEFING PAPER: "Public service pension age," by Julia Lourie and Djuna Thurley (SN02209, January 2012, .pdf format, 33p.).


9. STATISTICS NETHERLANDS ARTICLE: "More older people active online," (December 29, 2011).



A. "Supporting Caregivers and Caregiving in an Aging Canada," by Janice Keefe (November 2011, .pdf format, 35p.).

B. "Many Degrees of Policy Freedom: The Federal Governments Role in Care for Seniors," by Harvey Lazar (November 2011, .pdf format, 71p.).


11. AARP REPORT: "Trends in Retail Prices of Specialty Prescription Drugs Widely Used by Medicare Beneficiaries 2005 to 2009," by Stephen W. Schondelmeyer and Leigh Purvis (January 2012, .pdf format, 27p.).


12. METLIFE MATURE MARKET INSTITUTE REPORT: "Multi-Generational Views on Family Financial Obligations: A MetLife Survey of Baby Boomers and Members of Generations X and Y," (January 2012, .pdf format, 40p.).


13. EMPLOYEE BENEFIT RESEARCH INSTITUTE ARTICLE: "Spending Adjustments Made By Older Americans to Save Money," by Sudipto Banerjee (EBRI Notes, Vol. 33, No. 1, January 2012, .pdf format). Note: The other article in this issue is: "The Impact of PPACA on Employment-Based Health Coverage of Adult Children to Age 26," by Paul Fronstin.


14. CENTER FOR AGING RESEARCH AND DEVELOPMENT IN IRELAND (CARDI) E-LIBRARY UPDATE: CARDI e-library has updated its links to relevant papers from Jan. 5-12, 2012).


15. NATIONAL ACADEMY ON AN AGING SOCIETY NEWSLETTER: Public Policy & Aging E-Newsletter (Vol. 6, No. 1, January 2012, HTML format).


16. BULLETIN OF THE WORLD HEALTH ORGANIZATION ARTICLE: "Defusing the demographic 'time-bomb' in Germany," (Vol. 90, No. 1, January 2012, .pdf and HTML format, p. 6-7).




18. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES ARTICLE ABSTRACT: "A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction," by Salvatore Fusco, Cristian Ripoli, Maria Vittoria Podda, Sofia Chiatamone Ranieri, Lucia Leone, Gabriele Toietta, Michael W. McBurney, Gunther Schutz, Antonella Riccio, Claudio Grassi, Tommaso Galeotti, and Giovambattista Pan (Vol. 109, No. 2, January 10, 2012, p. 621-626).



A. "Fitness Memberships and Favorable Selection in Medicare Advantage Plans," by Alicia L. Cooper and Amal N. Trivedi (Vol. 366, No. 2, January 12, 2012, p. 150-157).

B. "Germline Mutations in HOXB13 and Prostate-Cancer Risk," by Charles M. Ewing, Anna M. Ray, Ethan M. Lange, Kimberly A. Zuhlke, Christiane M. Robbins, Waibhav D. Tembe, Kathleen E. Wiley, Sarah D. Isaacs, Dorhyun Johng, Yunfei Wang, Chris Bizon, Guifang Yan, Marta Gielzak, Alan W. Partin, Vijayalakshmi Shanmugam, Tyler Izatt, Shripad Sinari, David W. Craig, S. Lilly Zheng, Patrick C. Walsh, James E. Montie, Jianfeng Xu, John D. Carpten, William B. Isaacs, and Kathleen A. Cooney (Vol. 366, No. 2, January 12, 2012, p. 141-147).



A. "Association of Incident Dementia With Hospitalizations," by Elizabeth A. Phelan, Soo Borson, Louis Grothaus, Steven Balch, and Eric B. Larson (Vol. 307, No. 2, January 11, 2012, p. 165-172).

B. "Prognostic Indices for Older Adults: A Systematic Review," by Lindsey C. Yourman, Sei J. Lee, Mara A. Schonberg, Eric W. Widera, and Alexander K. Smith (Vol. 307, No. 2, January 11, 2012, p. 182-192).

C. "Prevention of Unnecessary Hospitalization for Patients With Dementia: The Role of Ambulatory Care," by Constantine G. Lyketsos (Vol. 307, No. 2, January 11, 2012, p. 197-198).


21. LANCET ARTICLE ABSTRACT: Note: Lancet requires free registration before providing content. "Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: results of a phase 3, randomised, placebo-controlled trial," by Matthew R. Smith, Fred Saad, Robert Coleman, Neal Shore, Karim Fizazi, Bertrand Tombal, Kurt Miller, Paul Sieber, Lawrence Karsh, Ronaldo Damiao, Teuvo L. Tammela, Blair Egerdie, Hendrik Van Poppel, Joseph Chin, Juan Morote, Francisco Gomez-Veiga, Tomasz Borkowski, Zhishen Ye, Amy Kupic, Roger Dansey, and Carsten Goessl (Vol. 379, No. 9810, January 7, 2012, p. 39-46).



A. "Conformational Altered p53 as an Early Marker of Oxidative Stress in Alzheimer's Disease," by Laura Buizza, Giovanna Cenini, Cristina Lanni, Giulia Ferrari-Toninelli, Chiara Prandelli, Stefano Govoni, Erica Buoso, Marco Racchi, Maria Barcikowska, Maria Styczynska, Aleksandra Szybinska, David Allan Butterfield, Maurizio Memo, and Daniela Uberti (PLoS ONE 7(1): e29789. doi:10.1371/journal.pone.0029789, XML, HTML, and .pdf format, 11p.).

B. "Modeling the Spread of Methicillin-Resistant Staphylococcus aureus in Nursing Homes for Elderly," by Farida Chamchod and Shigui Ruan (PLoS ONE 7(1): e29757. doi:10.1371/journal.pone.0029757, XML, HTML, and .pdf format, 9p.).

C. "Presenilin Is the Molecular Target of Acidic {gamma}-Secretase Modulators in Living Cells," by Thorsten Jumpertz, Andreas Rennhack, Julia Ness, Sandra Baches, Claus U. Pietrzik, Bruno Bulic, and Sascha Weggen (PLoS ONE 7(1): e30484. doi:10.1371/journal.pone.0030484, XML, HTML, and .pdf format, 9p.).

D. "Abnormal Activity in the Precuneus during Time Perception in Parkinson's Disease: An fMRI Study Petr Dusek, Robert Jech, Tomas Sieger, Josef Vymazal, Evzen Ruzicka, Jiri Wackermann, and Karsten Mueller (PLoS ONE 7(1): e29635. doi:10.1371/journal.pone.0029635, XML, HTML, and .pdf format, 8p.).

E. "Successful Cognitive Aging in Rats: A Role for mGluR5 Glutamate Receptors, Homer 1 Proteins and Downstream Signaling Pathways," by Caroline Menard and Remi Quirion (PLoS ONE 7(1): e28666. doi:10.1371/journal.pone.0028666, XML, HTML, and .pdf format, 15p.).

F. "Neuroretinal Rim Area and Body Mass Index," by Liang Xu, Ya X. Wang, Shuang Wang, and Jost B. Jonas (PLoS ONE 7(1): e30104. doi:10.1371/journal.pone.0030104, XML, HTML, and .pdf format, 5p.).

G. "Associations of Insulin and Insulin-Like Growth Factors with Physical Performance in Old Age in the Boyd Orr and Caerphilly Studies," by Kate Birnie, Yoav Ben-Shlomo, Jeff M. P. Holly, David Gunnell, Shah Ebrahim, Antony Bayer, John Gallacher, and Richard M. Martin (PLoS ONE 7(1): e30096. doi:10.1371/journal.pone.0030096, XML, HTML, and .pdf format, 9p.).

H. "High Prevalence of Clostridium difficile Colonization among Nursing Home Residents in Hesse, Germany," by Mardjan Arvand, Vera Moser, Christine Schwehn, Gudrun Bettge-Weller, Marjolein P. Hensgens, and Ed J. Kuijper (PLoS ONE 7(1): e30183. doi:10.1371/journal.pone.0030183, XML, HTML, and .pdf format, 6p.).

I. "Brain Training Game Improves Executive Functions and Processing Speed in the Elderly: A Randomized Controlled Trial," by Rui Nouchi, Yasuyuki Taki, Hikaru Takeuchi, Hiroshi Hashizume, Yuko Akitsuki, Yayoi Shigemune, Atsushi Sekiguchi, Yuka Kotozaki, Takashi Tsukiura, Yukihito Yomogida, and Ryuta Kawashima (PLoS ONE 7(1): e29676. doi:10.1371/journal.pone.0029676, XML, HTML, and .pdf format, 9p.).

J. "Comparing the Prognostic Accuracy for All-Cause Mortality of Frailty Instruments: A Multicentre 1-Year Follow-Up in Hospitalized Older Patients," by Alberto Pilotto, Franco Rengo, Niccolo Marchionni, Daniele Sancarlo, Andrea Fontana, Francesco Panza, and Luigi Ferrucci, on behalf of the FIRI-SIGG Study Group (PLoS ONE 7(1): e29090. doi:10.1371/journal.pone.0029090, XML, HTML, and .pdf format, 9p.).

K. "Dual Effect of Beta-Amyloid on {alpha}7 and {alpha}4{beta{2 Nicotinic Receptors Controlling the Release of Glutamate, Aspartate and GABA in Rat Hippocampus," by Elisa Mura, Stefania Zappettini, Stefania Preda, Fabrizio Biundo, Cristina Lanni, Massimo Grilli, Anna Cavallero, Guendalina Olivero, Alessia Salamone, Stefano Govoni, and Mario Marchi (PLoS ONE 7(1): e29661. doi:10.1371/journal.pone.0029661, XML, HTML, and .pdf format, 13p.).


III. Working Papers:

23. NATIONAL BUREAU OF ECONOMIC RESEARCH: "Education and Health: Insights from International Comparisons," by David M. Cutler and Adriana Lleras-Muney (w17738, January 2012, .pdf format, 46p.).


In this review we synthesize what is known about the relationship between education and health. A large number of studies from both rich and poor countries show that education is associated with better health. While previous work has thought of the effect of education separately for rich and poor countries, we argue that there are insights to be gained by integrating the two. For example, education is associated with lower malnutrition in most countries, but in richer countries the educated have lower BMIs whereas in poor countries the educated have higher BMIs. This suggests that the behaviors associated with better health differ depending on the level of development. We illustrate this approach by comparing the effects of education on various health and health behaviors around the world, to generate hypotheses about why education is so often (but not always) predictive of health. Finally, we review the empirical evidence on the relationship between education and health, paying particular attention to causal evidence and evidence on mechanisms linking education to better health.


24. CENTER FOR RETIREMENT RESEARCH AT BOSTON COLLEGE: "Understanding the Growth in Federal Disability Programs: Who Are the Marginal Beneficiaries and How Much Do They Cost?" by Adele Kirk (WP No. 12-1, January 2012, .pdf format, 29p.). Note: Links to the abstract and full-text can be found at:


25. PENSIONS INSTITUTE (CASS BUSINESS SCHOOL, CITY UNIVERSITY OF LONDON) [UK]: "The Design of Supplementary Pension Schemes in Poland and Longevity Risk: Current Situation and Proposed Changes," by Marek Szczepanski (Discussion Paper No. PI-1202, January 2012, .pdf format, 10p.).


The paper investigates the influence of the design of voluntary, supplementary pension schemes in Poland (occupational pension schemes, retirement savings accounts and the new individual pension protection accounts) on longevity risk. The author formulates the general conclusion that none of the analyzed supplementary pension schemes provides future pensioners with compulsory life annuities or other hedging instruments that could effectively mitigate longevity risk.

New capital market solutions are needed in Poland to deal with the longevity risk. The text includes some proposals of mortality-linked financial products for Polish market.


26. NEP-AGE: Working papers in the Economics of Aging are available through the bibliographic database provided by Research Papers in Economics (RePEc). The latest compilations are for Jan. 3, 2012.


IV. Journal Tables of Contents (check your library for availability):

27. Aging and Mental Health (Vol. 16, No. 2, 2012).

28. Ageing and Society (Vol. 32, No. 2, February 2012).

29. Experimental Aging Research (Vol. 38, No. 1, 2012).

30. Journal of Aging and Social Policy (Vol. 24, No. 1, 2012).

31. Journal of Gerontological Social Work (Vol. 55, No. 1, 2012).

32. Reviews in Clinical Gerontology (Vol. 22, No. 1, February 2012).


33. AMEDEO MEDICAL LITERATURE: Note: "AMEDEO has been created to serve the needs of healthcare professionals, including physicians, nurses, pharmacists, administrators, other members of the health professions, and patients and their friends. They can easily access timely, relevant information within their respective fields... All AMEDEO services are free of charge. This policy was made possible thanks to generous unrestricted educational grants provided by AMGEN, Berlex, Eisai, Glaxo Wellcome, Novartis, Pfizer, Roche, and Schering AG."

A. Osteoporosis: Literature for the week of January 9, 2012:

B. Alzheimer's Disease: Literature for the week of January 9, 2012:

C. Parkinson's Disease: Literature for the week of January 9, 2012:

D. Prostate Cancer: Literature for the week of January 9, 2012:

E. Stem Cell Research: Literature for the week of January 9, 2012:

F. Ophthalmology: Literature for the week of January 9, 2012:

AMEDEO Literature Guide:


V. Books:

34. ASIAN DEVELOPMENT BANK: Pension Systems and Old-Age Income Support in East and Southeast Asia: Overview and Reform Directions, edited by Donghyun Park (December 2011, 978-0-415-69270-0, 254p.). Note: A link is provided to ordering information from Routledge.


VI. Funding/Employment Opportunities:

35. AGEWORK.COM: AgeWork has updated its employment page with listings through Jan. 12, 2012.


VII. Conferences:

36. CONFERENCEALERTS.COM GERONTOLOGY CONFERENCES: has recently added the following gerontology related conferences:

Feb. 23, 2012: Advanced FORUM ON PENSION REFORM, LITIGATION AND GOVERNANCE -- Toronto, Canada.

Mar. 6, 2012: Healthy People Conference - Healthy Aging -- Loma Linda, California.

Apr. 4, 2012: Looking after older people: Rights and wrongs and 38th Albert Wander Lecture -- London, United Kingdom.

Apr. 18, 2012: III International Conference on Elderly and New Technologies -- Castell, Spain.

May 21, 2012: Actual problems of radiation and combined treatment of cancer and prevention of complications -- Kharkov, Ukraine.

May 28, 2012: Retirement Living World China 2012 -- Shanghai, China.

Nov. 15, 2012: International Conference of National Strategies for TORCH, Chlamydia trachomatis and human papilloma virus -- Kiev, Ukraine.


VIII. Websites of Interest:

37. ASSOCIATION OF PUBLIC DATA USERS WEBINAR: "Pensions: The National Debate, Heres the Data," (January 25, 2012, 3-4pm). Note: Pre-registration is required.





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