Current Awareness in Aging Research (CAAR) Report #600 -- August 11, 2011

CAAR (Current Awareness in Aging Research) is a weekly email report produced by the Center for Demography of Health and Aging at the University of Wisconsin-Madison that helps researchers keep up to date with the latest developments in the field. For more information, including an archive of back issues and subscription information see:


I. Data:

1. US CENTERS FOR MEDICARE AND MEDICAID SERVICES STATISTICAL SUPPLEMENT UPDATES: "Medicare Enrollment," (2011 Edition, Tables 2.1-2.8, .zip compressed Microsoft Excel and .pdf format).


II. Reports and articles:

2. US SOCIAL SECURITY ADMINISTRATION REPORT: "Fast Facts & Figures About Social Security, 2011," (August 2011, .pdf format, 36p.).



A. "Incapacitated Adults: Oversight of Federal Fiduciaries and Court-Appointed Guardians Needs Improvement," (GAO-11-678 July 2011, .pdf format, 32p.).

B. "Long-Term Care Insurance: Carrier Interest in the Federal Program, Changes to Its Actuarial Assumptions, and OPM Oversight," (GAO-11-630, July 2011, .pdf format, 54p.).



A. "CBO's 2011 Long-Term Projections for Social Security: Additional Information," (August 2011, .pdf format, 22p.).

B. "CBO's 2011 Long-Term Projections for Social Security: Infographic," (August 2011, .pdf format, 6p.).


5. UK DEPARTMENT OF WORK AND PENSIONS REPORT: "Qualitative Research into enhanced Jobseeker's Allowance provision for the 50+," by Andrew Thomas and Alison Pemberton (Research Report No. 766, August 2011, .pdf format, 70p.).


6. UK DEPARTMENT OF HEALTH AND WELFARE REPORT: "Differences in life expectancy between those aged 20, 50 and 80," by James Evans (August 2011, .pdf format, 5p.).


7. UK HIGH PAY COMMISSION REPORT: "Directors' Pensions: In it for themselves?" (August 2011, .pdf format, 17p.).


8. AUSTRALIAN PRODUCTIVITY COMMISSION REPORT: "Caring for Older Australians," (August 2011, .pdf and Word format, Vol. I 138p., Vol. II 566p.).



A. "Trends in Life Expectancy in the United States, Denmark, and the Netherlands: Rapid Increase, Stagnation, and Resumption," by Toshiko Kaneda and Paola Scommegna (Today's Research on Aging, No. 22, August 2011, .pdf format, 5p.).

B. "Volunteering and Health for Aging Populations," by Mary Kent (Today's Research on Aging, No. 21, August 2011, .pdf format, 7p.).


10. CENTER FOR AGING RESEARCH AND DEVELOPMENT IN IRELAND (CARDI) E-LIBRARY UPDATE: CARDI e-library has updated its links to relevant papers from Aug. 5-Aug. 11, 2011).


11. DEMOGRAPHIC RESEARCH ARTICLE: "Occupational inequalities in health expectancies in France in the early 2000s: Unequal chances of reaching and living retirement in good health," by Emmanuelle Cambois, Caroline Laborde, Isabelle Romieu, and Jean-Marie Robine (Vol. 25, Article 12, August 2011, .pdf format, p. 407-436).


12. FAMILY CAREGIVER ALLIANCE PERIODICAL: Caregiving Policy Digest (Vol. 11, No. 14, Aug. 3, 2011).


13. SCIENCE REPORT ABSTRACT: "Nicotinic Acetylcholine Receptor Subunits in the Medial Prefrontal Cortex Control Attention," by Karine Guillem, Bernard Bloem, Rogier B. Poorthuis, Maarten Loos, August B. Smit, Uwe Maskos, Sabine Spijker, and Huibert D. Mansvelder (Vol. 333, No. 6044, August 12, 2011, p. 888-891).



A. "Neuronal basis of age-related working memory decline," by Min Wang, Nao J. Gamo, Yang Yang, Lu E. Jin, Xiao-Jing Wang, Mark Laubach, James A. Mazer, Daeyeol Lee & Amy F. T. Arnsten (Vol. 476, No. 7359, August 11, 2011, p. 210-213).

B. "Direct generation of functional dopaminergic neurons from mouse and human fibroblasts," by Massimiliano Caiazzo, Maria Teresa DellAnno, Elena Dvoretskova, Dejan Lazarevic, Stefano Taverna, Damiana Leo, Tatyana D. Sotnikova, Andrea Menegon, Paola Roncaglia, Giorgia Colciago, Giovanni Russo, Piero Carninci, Gianni Pezzoli, Raul R. Gainetdinov, Stefano Gustincich, Alexander Dityatev, & Vania Broccoli (Vol. 476, No. 7359, August 11, 2011, p. 224-227).



A. "Constitutive cAMP response element binding protein (CREB) activation by Alzheimer's disease presenilin-driven inositol trisphosphate receptor (InsP3R) Ca2+ signaling," by Marioly Muller, Cesar Cardenas, Lijuan Mei, King-Ho Cheung, and J. Kevin Foskett (Vol. 108, No. 32, August 9, 2011, p. 13293-13298).

B. "Aging of the cerebral cortex differs between humans and chimpanzees," by Chet C. Sherwood, Adam D. Gordon, John S. Allen, Kimberley A. Phillips, Joseph M. Erwin, Patrick R. Hof, and William D. Hopkins (Vol. 108, No. 32, August 9, 2011, p. 13029-13034).



A. "Development and Validation of a New Method to Measure Walking Speed in Free-Living Environments Using the Actibelt Platform," by Michaela Schimpl, Christian Lederer, and Martin Daumer (PLoS ONE 6(8): e23080. doi:10.1371/journal.pone.0023080, HTML, XML, and .pdf format, 12p.).

B. "Dysregulation in Retinal Para-Inflammation and Age-Related Retinal Degeneration in CCL2 or CCR2 Deficient Mice," by Mei Chen, John V. Forrester, and Heping Xu (PLoS ONE 6(8): e22818. doi:10.1371/journal.pone.0022818, XML, HTML, and .pdf format, 15p.).

C. "Confocal Fluorescence Anisotropy and FRAP Imaging of {alpha}-Synuclein Amyloid Aggregates in Living Cells," by M. Julia Roberti, Thomas M. Jovin, and Elizabeth Jares-Erijman (PLoS ONE 6(8): e23338. doi:10.1371/journal.pone.0023338, XML, HTML, and .pdf format, 7p.).

D. "Voluntary Wheel Running Reverses Age-Induced Changes in Hippocampal Gene Expression," by Rachel A. Kohman, Sandra L. Rodriguez-Zas, Bruce R. Southey, Keith W. Kelley, Robert Dantzer, and Justin S. Rhodes (PLoS ONE 6(8): e22654. doi:10.1371/journal.pone.0022654, XML, HTML, and .pdf format, 10p.).

E. "The Influence of Cognition, Anxiety and Psychiatric Disorders over Treatment Adherence in Uncontrolled Hypertensive Patients," by Ursula Jacobs, Mauro S. De Castro, Flavio D. Fuchs, and Maria Beatriz C. Ferreira (PLoS ONE 6(8): e22925. doi:10.1371/journal.pone.0022925, XML, HTML, and .pdf format, 4p.).

F. "Targeted Over-Expression of Glutamate Transporter 1 (GLT-1) Reduces Ischemic Brain Injury in a Rat Model of Stroke," by Brandon K. Harvey, Mikko Airavaara, Jason Hinzman, Emily M. Wires, Matthew J. Chiocco, Douglas B. Howard, Hui Shen, Greg Gerhardt, Barry J. Hoffer, and Yun Wang (PLoS ONE 6(8): e22135. doi:10.1371/journal.pone.0022135, XML, HTML, and .pdf format, 7p.).


17. JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION ARTICLE ABSTRACT: "Sleep-Disordered Breathing, Hypoxia, and Risk of Mild Cognitive Impairment and Dementia in Older Women," by Kristine Yaffe, Alison M. Laffan, Stephanie Litwack Harrison, Susan Redline, Adam P. Spira, Kristine E. Ensrud, Sonia Ancoli-Israel, and Katie L. Stone (Vol. 306, No. 6, August 10, 2011, p. 613-619).


III. Working Papers:

18. NATIONAL BUREAU OF ECONOMIC RESEARCH: "Healthy, Wealthy and Wise?" Revisited: An Analysis of the Causal Pathways from Socio-economic Status to Health," by Till Stowasser, Florian Heiss, Daniel McFadden, and Joachim Winter (w17273, August 2011, .pdf format, 36p.).


Much has been said about the stylized fact that the economically successful are not only wealthier but also healthier than the less affluent. There is little doubt about the existence of this socio-economic gradient in health, but there remains a vivid debate about its source. In this paper, we review the methodological challenges involved in testing the causal relationships between socio-economic status and health. We describe the approach of testing for the absence of causal channels developed by Adams et al. (2003) that seeks identification without the need to isolate exogenous variation in economic variables, and we repeat their analysis using the full range of data that have become available in the Health and Retirement Study since, both in terms of observations years and age ranges covered. This analysis shows that causal inference critically depends on which time periods are used for estimation. Using the information of longer panels has the greatest effect on results. We find that SES causality cannot be ruled out for a larger number of health conditions than in the original study. An approach based on a reduced-form interpretation of causality thus is not very informative, at least as long as the confounding influence of hidden common factors is not fully controlled.


19. COLLEGE OF BUSINESS AND ECONOMICS [AUSTRALIAN NATIONAL UNIVERSITY]: "Trade-Offs in Means Tested Pension Design," by Chung Tran and Alan Woodland (Working Paper No. 550, August 2011, .pdf format, 36p.). Note: Links to the abstract and full-text can be found at:


20. NEP-AGE: Working papers in the Economics of Aging are available through the bibliographic database provided by Research Papers in Economics (RePEc). The latest compilations are for Aug. 2, 2011.


IV. Journal Tables of Contents (check your library for availability):

21. Age and Ageing (Vol. 40, No. 5, September 2011).

22. American Journal of Public Health (Vol. 101, No. 9, September 1, 2011).

23. Journal of Gerontology (A): Biological Sciences (Vol. 66A, No. 8, August 2011).


24. AMEDEO MEDICAL LITERATURE: Note: "AMEDEO has been created to serve the needs of healthcare professionals, including physicians, nurses, pharmacists, administrators, other members of the health professions, and patients and their friends. They can easily access timely, relevant information within their respective fields... All AMEDEO services are free of charge. This policy was made possible thanks to generous unrestricted educational grants provided by AMGEN, Berlex, Eisai, Glaxo Wellcome, Novartis, Pfizer, Roche, and Schering AG."

A. Osteoporosis: Literature for the week of August 8, 2011:

B. Alzheimer's Disease: Literature for the week of August 8, 2011:

C. Parkinson's Disease: Literature for the week of August 8, 2011:

D. Prostate Cancer: Literature for the week of August 8, 2011:

E. Stem Cell Research: Literature for the week of August 8, 2011:

F. Ophthalmology: Literature for the week of August 8, 2011:

AMEDEO Literature Guide:


V. Funding/Employment Opportunities:


A. "Paul B. Beeson Clinical Scientist Development Award in Aging (K08)," (RFA-AG-12-003, a reissue of RFA-AG-11-008, National Institute on Aging, in conjunction with other agencies, applications are due Oct. 27, 2011). Note: There is a companion award "Paul B. Beeson Patient-Oriented Research Career Development Award in Aging (K23)," (RFA-AG-12-003, a reissue of RFA-AG-11-009). A link to that program announcement is included under "Companion FOA."

B. "Secondary Analyses and Archiving of Social and Behavioral Datasets in Aging (R03)," (RFA-AG-12-005, National Institute on Aging, applications due date is Nov. 3, 2011).

C. "Human Cell Reprogramming for Aging and Alzheimer's Disease Research (R21)," (RFA-AG-12-008, National Institute on Aging, applications due date is Nov. 2, 2011).

D. "T1 Translational Research on Aging: Small Business Innovation Awards (R43/R44)," (RFA-AG-12-009, National Institute on Aging, applications due date is Nov. 4, 2011). Note: There is a companion award "T2 Translational Research on Aging: Small Business Innovation Awards (R43/R44)," (RFA-AG-12-010, National Institute on Aging). A link to that program announcement is included under "Companion FOA."

E. "Demonstration Projects for Systems Biology of Aging in Saccharomyces cerevisiae (R01)," (RFA-AG-12-011, National Institute on Aging, applications due date is Nov. 4, 2011).


26. AGEWORK.COM: AgeWork has updated its employment page with listings through Aug. 10, 2011.


VI. Websites of Interest:

27. MEDICARE.GOV WEBSITE UPDATES: The following sites were updated on Aug. 5, 2011: "Nursing Home Compare" and the "Department of Veterans Affairs (VA) Hospital Compare."


28. PANEL STUDY OF INCOME DYNAMICS BIBLIOGRAPHY UPDATE: The University of Michigan Institute for Social Research PSID has recently added the following item to its bibliography. The entire bibliography can be searched or browsed in various ways at:

Donohue III, John J.; Stein, Michael Ashley; Griffin, Jr., Christopher L., and Becker, Sascha. Assessing Post-ADA Employment: Some Econometric Evidence and Policy Considerations. Journal of Empirical Legal Studies. 2011; 9, (3):477-503.

Pan, Jie and Wagner, Gary A. The Effect of State Tax Preferences on the Living Arrangements of Elderly Individuals. International Advances in Economic Research. 2011; 17, (2):193-.





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