Current Awareness in Aging Research (CAAR) Report #598 -- July 28, 2011

CAAR (Current Awareness in Aging Research) is a weekly email report produced by the Center for Demography of Health and Aging at the University of Wisconsin-Madison that helps researchers keep up to date with the latest developments in the field. For more information, including an archive of back issues and subscription information see:


I. Data:

1. NATIONAL HEALTH AND AGING TRENDS STUDY [JOHNS HOPKINS UNIVERSITY BLOOMBERG SCHOOL OF PUBLIC HEALTH] CALL FOR MODULES: "Call for Proposed Supplemental Modules for the 2012 National Health and Aging Trends Study (NHATS). The National Health and Aging Trends Study (NHATS) is a new national study of functioning in later life supported by the National Institute on Aging (NIA). The NHATS design allows for researchers to propose brief supplemental data collection modules for inclusion in each annual wave of the survey. Proposals are due September 15, 2011 to Judith Kasper (, Principal Investigator of NHATS." For details see:


2. MISSOURI STATE DATA CENTER UPDATE: "MSDC has recently released "Standard Summary File 1 (2010 Census) Extract Assistant." "This application is intended for the more casual user of census data who just want to create a spreadsheet, and/or possibly a SAS or SPSS data set, containing basic data for specific geographic units within a specified state. The data items ("variables" or columns) are a distillation of the much larger and detailed summary files as released by the Census Bureau. Instead of hundreds of detailed tables with thousands of data cells (which are also available on our site in the sf12010 filetype directory) we offer access to about 200 key columns/variables per geographic area, about half of which are derived percentages. This front end takes care of choosing the appropriate data set for you (based on the state and geographic summary unit(s) you choose), handles the generation of a "filter" to select the geographic unit(s) that you choose here from a select list, and then creates the list of variables by topic that you choose here (and even takes care of ignoring any variables that may not be available for smaller sub-tract units). You could use this application then to easily generate (for example) an Excel spreadsheet containing basic data regarding population trends, race and hispanic origin for the state and all counties in California Or, you could use it to generate a SAS data set with all 200+ variables for all the counties, county subdivisions (towns) and ZIP codes (ZCTAs) in Pennsylvania."


II. Reports and articles:


A. "Comparison of Fourth-Quarter 2010 Average Sales Prices and Average Manufacturer Prices: Impact on Medicare Reimbursement for Second Quarter 2011," (OEI-03-11-00360, July 2011, .pdf format, 22p.).

B. "Medicare Prescription Drug Sponsors' Training To Prevent Fraud, Waste, and Abuse," (OEI-01-10-00060, July 2011, .pdf format, 23p.).


4. US GOVERNMENT ACCOUNTABILITY OFFICE CORRESPONDENCE: "Medicare Part D: Changes in Utilization Similar for Randomly Reassigned and Other Low-Income Subsidy Beneficiaries," (GAO-11-546R, June 2011, .pdf format, 21p.).


5. US CENTERS FOR MEDICARE AND MEDICAID SERVICES FINAL DECISION MEMORANDUM: "Decision Memo for Prothrombin Time (PT) (Addition of two ICD-9-CM diagnosis codes) (CAG-00428N)," (July 21, 2011).


6. MEDICAL EXPENDITURE PANEL SURVEY STATISTICAL BRIEF: "Employer-Sponsored Health Insurance for Early Retirees in the Private Sector, 2004 and 2009," by Karen E. Davis (Statistical Brief No. 333, July 2011, .pdf and HTML format, 5p.).


7. NATIONAL SCIENCE FOUNDATION PRESS RELEASE: "Aging Brains Are Different in Humans and Chimpanzees," (July 25, 2011).


8. US NATIONAL INSTITUTES OF HEALTH PRESS RELEASE: "NIH researchers trace early journey of modulating cells in brain," (July 26, 2011).


9. STATISTICS CANADA/STATISTIQUE CANADA REPORT CHAPTER: "Senior Women," by Anne Milan and Mireille Vina (appears in Women in Canada: A Gender-based Statistical Report, July 2011, .pdf and HTML format, 37p.).


10. MINISTRY OF MANPOWER [SINGAPORE] REPORT: "Retirement and Re-employment Practices - 2010," (Paper 1/11, July 2011, .pdf format, 28p.).


11. OFFICE OF THE OMBUDSMAN [IRELAND] REPORT: "Too Old to be Equal? An Ombudsman investigation into the illegal refusal of Mobility Allowance to people over 66 years of age," (July 2011, .pdf format, 39p.).



A. "Public service pension reform - 2010 onwards," by Richard Cracknell and Djuna Thurley (SN05768, July 2011, .pdf format, 50p.).

B. "Local Government Pension Scheme, 2010 onwards," by Djuna Thurley (SN05823, July 2011, .pdf format, 21p.).


13. ORGANISATION FOR ECONOMIC CO-OPERATION AND DEVELOPMENT PERIODICAL: Pension Markets in Focus (No. 8, July 2011, .pdf format, 23p.).


14. MATURE MARKET INSTITUTE REPORT: "The MetLife Report on American Grandparents: New Insights for a New Generation of Grandparents," (July 2011, .pdf format, 20p.).



A. "Comparison of Medicare Provisions in Deficit and Debt Reduction Proposals," (July 2011, .pdf format, 11p.).

B. "Medigap Reforms: Potential Effects of Benefit Restrictions on Medicare Spending and Beneficiary Costs," (July 2011, .pdf format, 21p.).

C. "Raising the Age of Medicare Eligibility: A Fresh Look Following Implementation of Health Reform," (July 2011, .pdf format, 27p.).



A. "AARP Rx Price Watch Report: Tracking Retail Price Changes for Widely Used Prescription Drugs," by Stephen W. Schondelmeyer and Leigh Purvis (July 2011, .pdf format, 21p.).

B. "Valuing the Invaluable: 2011 Update - The Growing Contributions and Costs of Family Caregiving," by Lynn Feinberg, Susan C. Reinhard, Ari Houser, and Rita Choula (July 2011, .pdf format, 28p.).


17. INSTITUTE FOR WOMEN'S POLICY RESEARCH REPORT: "Pension Crediting for Caregivers: Policies in Finland, France, Germany, Sweden, the United Kingdom, Canada, and Japan," by Elaine Fultz (June 2011, .pdf format, 38p.).

More information about the Institute:


18. CENTER FOR AGING RESEARCH AND DEVELOPMENT IN IRELAND (CARDI) E-LIBRARY UPDATE: CARDI e-library has updated its links to relevant papers from Jul. 22-28, 2011).


19. DEMOGRAPHIC RESEARCH ARTICLE: "Gender differences in social mortality differentials in Switzerland (1990-2005)," by Reto Schumacher and Sarah Vilpert (Vol. 25, Article 8, July 2011, .pdf format, p. 285-310).


20. NATURE NEUROSCIENCE ARTICLE ABSTRACT: "Potent amyloidogenicity and pathogenicity of A[beta]43," by Takashi Saito, Takahiro Suemoto, Nathalie Brouwers, Kristel Sleegers, Satoru Funamoto, Naomi Mihira, Yukio Matsuba, Kazuyuki Yamada, Per Nilsson, Jiro Takano, Masaki Nishimura, Nobuhisa Iwata, Christine Van Broeckhoven, Yasuo Ihara and Takaomi C. Saido (Vol. 14, No. 8, August 2011, p. 1023-1032).



A. "Methods for Structuring Scientific Knowledge from Many Areas Related to Aging Research," by Alex Zhavoronkov and Charles R. Cantor (PLoS ONE 6(7): e22597.doi:10.1371/journal.pone.0022597, XML, HTML, and .pdf format, 9p.).

B. "Sensitivity and Specificity of Medial Temporal Lobe Visual Ratings and Multivariate Regional MRI Classification in Alzheimer's Disease," by Eric Westman, Lena Cavallin, J-Sebastian Muehlboeck, Yi Zhang, Patrizia Mecocci, Bruno Vellas, Magda Tsolaki, Iwona Kloszewska, Hilkka Soininen, Christian Spenger, Simon Lovestone, Andrew Simmons, and Lars-Olof Wahlund, for the AddNeuroMed consortium (PLoS ONE 6(7): e22506. doi:10.1371/journal.pone.0022506, XML, HTML, and .pdf format, 9p.).

C. "Epigenetic Silencing of Nucleolar rRNA Genes in Alzheimer's Disease," by Maciej Pietrzak, Grzegorz Rempala, Peter T. Nelson, Jing-Juan Zheng, and Michal Hetman (PLoS ONE 6(7): e22585. doi:10.1371/journal.pone.0022585, XML, HTML, and .pdf format, 10p.).

D. "Structural Integrity of the Uncinate Fasciculus and Resting State Functional Connectivity of the Ventral Prefrontal Cortex in Late Life Depression," by David C. Steffens, Warren D. Taylor, Kevin L. Denny, Sara R. Bergman, and Lihong Wang (PLoS ONE 6(7): e22697. doi:10.1371/journal.pone.0022697, XML, HTML, and .pdf format, 6p.).

E. "Identification of Conversion from Mild Cognitive Impairment to Alzheimer's Disease Using Multivariate Predictors," by Yue Cui, Bing Liu, Suhuai Luo, Xiantong Zhen, Ming Fan, Tao Liu, Wanlin Zhu, Mira Park, Tianzi Jiang, and Jesse S. Jin, the Alzheimer's Disease Neuroimaging Initiative (PLoS ONE 6(7): e21896. doi:10.1371/journal.pone.0021896, XML, HTML, and .pdf format, 10p.).

F. "Rivastigmine Lowers A{beta} and Increases sAPPa Levels, Which Parallel Elevated Synaptic Markers and Metabolic Activity in Degenerating Primary Rat Neurons," by Jason A. Bailey, Balmiki Ray, Nigel H. Greig, and Debomoy K. Lahiri (PLoS ONE 6(7): e21954. doi:10.1371/journal.pone.0021954, XML, HTML, and .pdf format, 12p.).

G. "Rationally Designed Turn Promoting Mutation in the Amyloid-{beta} Peptide Sequence Stabilizes Oligomers in Solution," by Jayakumar Rajadas, Corey W. Liu, Paul Novick, Nicholas W. Kelley, Mohammed Inayathullah, Melburne C. LeMieux, and Vijay S. Pande (PLoS ONE 6(7): e21776. doi:10.1371/journal.pone.0021776, XML, HTML, and .pdf format, 8p.).

H. "Runs of Homozygosity Do Not Influence Survival to Old Age," by Maris Kuningas, Ruth McQuillan, James F. Wilson, Albert Hofman, Cornelia M. van Duijn, AndrG. Uitterlinden, and Henning Tiemeier (PLoS ONE 6(7): e22580. doi:10.1371/journal.pone.0022580, HTML, XML, and .pdf format, 3p.).

I. "The Epidemic of Hip Fractures: Are We on the Right Track?" by Klaas A. Hartholt, Christian Oudshoorn, Stephanie M. Zielinski, Paul T. P. W. Burgers, Martien J. M. Panneman, Ed F. van Beeck, Peter Patka, and Tischa J. M. van der Cammen (PLoS ONE 6(7): e22227. doi:10.1371/journal.pone.0022227, HTML, XML, and .pdf format, 6p.).

J. "Auditory Feedback Control of Vocal Pitch during Sustained Vocalization: A Cross-Sectional Study of Adult Aging," by Peng Liu, Zhaocong Chen, Jeffery A. Jones, Dongfeng Huang, and Hanjun Liu (PLoS ONE 6(7): e22791. doi:10.1371/journal.pone.0022791, XML, HTML, and .pdf format, 8p.).

K. "Different Factors Affecting Human ANP Amyloid Aggregation and Their Implications in Congestive Heart Failure," by Lia Millucci, Eugenio Paccagnini, Lorenzo Ghezzi, Giulia Bernardini, Daniela Braconi, Marcella Laschi, Marco Consumi, Adriano Spreafico, Piero Tanganelli, Pietro Lupetti, Agnese Magnani, and Annalisa Santucci (PLoS ONE 6(7): e21870. doi:10.1371/journal.pone.0021870, XML, HTML, and .pdf format, 12p.).

L. "ApoB100/LDLR-/- Hypercholesterolaemic Mice as a Model for Mild Cognitive Impairment and Neuronal Damage," by Carlos Ramez, Saleta Sierra, Inmaculada Tercero, Jose Antonio Vquez, Antonia Pineda, Tatiana Manrique, and Javier S. Burgos (PLoS ONE 6(7): e22712. doi:10.1371/journal.pone.0022712, XML, HTML, and .pdf format, 10p.).

M. "Accelerated Telomere Attrition Is Associated with Relative Household Income, Diet and Inflammation in the pSoBid Cohort," by Paul G. Shiels, Liane M. McGlynn, Alan MacIntyre, Paul C. D. Johnson, G. David Batty, Harry Burns, Jonathan Cavanagh, Kevin A. Deans, Ian Ford, Alex McConnachie, Agnes McGinty, Jennifer S. McLean, Keith Millar, Naveed Sattar, Carol Tannahill, Yoga N. Velupillai, and Chris J. Packard (PLoS ONE 6(7): e22521. doi:10.1371/journal.pone.0022521, XML, HTML, and .pdf format, 7p.).


22. BRITISH MEDICAL JOURNAL ARTICLE: "Efficacy of treating pain to reduce behavioural disturbances in residents of nursing homes with dementia: cluster randomised clinical trial," by Bettina S. Husebo, Clive Ballard, Reidun Sandvik, Odd Bjarte Nilsen, and Dag Aarsland (BMJ 2011; 343:d4065, HTML and .pdf format).


23. LANCET ARTICLE ABSTRACT: Note: Lancet requires free registration before providing content. "Urinary incontinence in men after formal one-to-one pelvic-floor muscle training following radical prostatectomy or transurethral resection of the prostate (MAPS): two parallel randomised controlled trials," by Cathryn Glazener, Charles Boachie, Brian Buckley, Claire Cochran, Grace Dorey, Adrian Grant, Suzanne Hagen, Mary Kilonzo, Alison McDonald, Gladys McPherson, Katherine Moore, John Norrie, Craig Ramsay, Luke Vale, and James N'Dow (Vol. 378, No. 9788, July 23, 2011, p. 328-337).


24. JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION ARTICLE ABSTRACT: "Implementation of Medicare Part D and Nondrug Medical Spending for Elderly Adults With Limited Prior Drug Coverage," by J. Michael McWilliams, Alan M. Zaslavsky, and Haiden A. Huskamp (Vol. 306, No. 4, July 27, 2011, p. 402-409).


III. Working Papers:

25. NATIONAL BUREAU OF ECONOMIC ANALYSIS: "How Survey Design Affects Inference Regarding Health Perceptions and Outcomes," by Anneke Exterkate and Robin L. Lumsdaine (w17244, July 2011, .pdf format, 50p.).


This paper considers the role of survey design and question phrasing in evaluating the subjective health assessment responses using the Survey of Health, Ageing and Retirement in Europe (SHARE) dataset. A unique feature of this dataset is that respondents were twice asked during the survey to evaluate their health on a five-point scale, using two different sets of descriptors to define the five points, with the ordering of which set was first given determined randomly. We find no evidence to refute the assertion that the order was determined by random assignment. Yet we document differences in the response distributions between the two questions, as well as differences in inference in comparing the two populations (those that were asked one question first versus those that were asked the other). We then consider determinants of the degree of concordance between the two questions, as well as the determinants of individuals that provide conflicting responses. There appears to be evidence to suggest that individuals' assessments of their health in response to the second question may be influenced by the battery of health questions that were asked following the first assessment. We find that information in self-assessed health responses is useful in examining health outcomes. Our results suggest that adjusting such responses to take into account framing and sequencing of questions may improve inference. In addition, we show that accounting for survey design may be important in models for predicting outcomes of interest, such as the probability of a major health event.



A. "Longevity, Life-Cycle Behavior and Pension Reform," by Peter Haan and Victoria L. Prowse (Discussion Paper No. 5858, July 2011, .pdf format, 39p.). Note: Links to the abstract and full-text can be found at:

B. "Does Raising the Retirement Age Increase Employment of Older Workers?" by Stefan Staubli and Josef Zweimuller (Discussion Paper No. 5863, July 2011, .pdf format, 47p.). Note: Links to the abstract and full-text can be found at:


27. INSTITUTE FOR FISCAL STUDIES [LONDON, UK]: "Disability, health and retirement in the United Kingdom," by James Banks, Richard Blundell, Antoine Bozio and Carl Emmerson (W11/12, July 2011, .pdf format, 37p.). Note: Links to the abstract and full-text can be found at:


28. NEP-AGE: Working papers in the Economics of Aging are available through the bibliographic database provided by Research Papers in Economics (RePEc). The latest compilations are for Jul. 21, 2011.


IV. Journal Tables of Contents (check your library for availability):

29. American Journal of Epidemiology (Vol. 174, No. 3, Aug. 1, 2011).

30. American Journal of Geriatric Psychiatry (Vol. 19, No. 8, August 2011).

31. Alzheimer's and Dementia: The Journal of the Alzheimer's Association (Vol. 7, No. 4, July 2011).

32. Dementia (Vol. 10, No. 3, August 2011).

33. Journal of Population Ageing (Vol. 4, Nos. 1 & 2, June 2011).

34. Research on Aging (Vol. 33, No. 5, September 2011).

35. Review of Economics and Statistics (Vol. 93, No. 3, August 2011).


36. AMEDEO MEDICAL LITERATURE: Note: "AMEDEO has been created to serve the needs of healthcare professionals, including physicians, nurses, pharmacists, administrators, other members of the health professions, and patients and their friends. They can easily access timely, relevant information within their respective fields... All AMEDEO services are free of charge. This policy was made possible thanks to generous unrestricted educational grants provided by AMGEN, Berlex, Eisai, Glaxo Wellcome, Novartis, Pfizer, Roche, and Schering AG."

A. Osteoporosis: Literature for the week of July 25, 2011:

B. Alzheimer's Disease: Literature for the week of July 25, 2011:

C. Parkinson's Disease: Literature for the week of July 25, 2011:

D. Prostate Cancer: Literature for the week of July 25, 2011:

E. Stem Cell Research: Literature for the week of July 25, 2011:

F. Ophthalmology: Literature for the week of July 25, 2011:

AMEDEO Literature Guide:


V. Funding/Employment Opportunities:


A. "NIH Exploratory/Developmental Research Grant Program (Parent R21)," (PA-11-261, a reissue of PA-10-069, National Institute on Aging, in conjunction with other agencies, multiple application deadlines).

B. "Leveraging Existing Data or Longitudinal Studies to Evaluate Safety and Effectiveness of Pharmacological Management of Chronic Pain in Older Adults (R03)," (RFA-AG-12-006, National Institute on Aging, application deadline Nov. 3, 2011).

C. "Ethical, Legal, and Social Implications (ELSI) of Genomic Research Small Research Grant Program (R03), (PA-11-249, a reissue of PA-08-013, National Institute on Aging, in conjunction with other agencies, multiple application deadlines).

D. "Ethical, Legal, and Social Implications (ELSI) of Genomic Research Small Research Grant Program (R01), (PA-11-250, a reissue of PA-08-012, National Institute on Aging, in conjunction with other agencies, multiple application deadlines).

E. "Ethical, Legal, and Social Implications (ELSI) of Genomic Research Exploratory/Developmental Research Grant Award (R21)," (PA-11-251, National Institute on Aging, in conjunction with other agencies, multiple application deadlines).

F. "Research Project Grant (Parent R01)," (PA-11-260, a reissue of PA-10-067, National Institute on Aging, in conjunction with other agencies, multiple application deadlines).

G. "NIH Small Research Grant Program (Parent R03)," (PA-11-262, a reissue of PA-10-064, National Institute on Aging, in conjunction with other agencies, multiple application deadlines).

H. "Sleep and Social Environment: Basic Biopsychosocial Processes (R21)," (RFA-HD-12-204, a reissue of RFA-HD-11-102, National Institute on Aging, in conjunction with other agencies, application deadline Sept. 30, 2011).

I. "Building Interdisciplinary Research Careers in Women's Health (K12)," (RFA-OD-11-002, a reissue of RFA-OD-06-004, National Institute on Aging, in conjunction with other agencies, application deadline Sept. 20, 2011).

J. "T1 Translational Research: Novel interventions for prevention and treatment of age-related conditions (R21)," (PAS-11-280, National Institute on Aging, multiple application deadlines).

K. "T2 Translational Research: Research leading to new health care practices, community programs and policies affecting older persons (R21)," (PAS-11-281, National Institute on Aging, multiple application deadlines).


38. AGEWORK.COM: AgeWork has updated its employment page with listings through July 27, 2011.


VI. Conferences:

39. CENTER FOR RETIREMENT RESEARCH AT BOSTON COLLEGE: "2011 Retirement Research Consortium," (August 4-5, 2011; Washington, DC).


40. US NATIONAL INSTITUTE OF NURSING RESEARCH: "National Institute of Nursing Research convenes national summit on The Science of Compassion: Future Directions in End-of-Life and Palliative Care," (to be held August 10-12, 2011, Washington, DC). Registration is required. For More information go to:


VII. Legislation Information Updates:

41. US HOUSE COMMITTEE ON OVERSIGHT, SUBCOMMITTEE ON GOVERNMENT ORGANIZATION, EFFICIENCY AND FINANCIAL MANAGEMENT HEARING TESTIMONY: "Improper Medicare Payments: $48 Billion in Waste?" a hearing held July 28, 2011 (witness statements are available in .pdf format).


VIII. Websites of Interest:

42. PANEL STUDY OF INCOME DYNAMICS BIBLIOGRAPHY UPDATE: The University of Michigan Institute for Social Research PSID has recently added the following item to its bibliography. The entire bibliography can be searched or browsed in various ways at:

Jin, Fangyi. Revisiting the Composition Puzzles of the Household Portfolio: New Evidence. Review of Financial Economics. 2011; 20, (2):63-73.





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