Current Awareness in Aging Research (CAAR) Report #447--July 24, 2008

CAAR (Current Awareness in Aging Research) is a weekly email report produced by the Center for Demography of Health and Aging at the University of Wisconsin-Madison that helps researchers keep up to date with the latest developments in the field. For more information, including an archive of back issues and subscription information see:


I. Data:

1. ADMINISTRATION ON AGING: "U.S. Population Estimates for States by Age: July 1, 2007," (July 2008, Excel format).



A. "Details for Medicare Enrollment, 2008," (Tables 2.1-2.8, July 2008, .pdf and zipped .pdf and Excel format).

B. "Details for Figures 2.1-2.3 Medicare Enrollment," (Figure 2.1-2.3, July 2008, .pdf and zipped .pdf format).


3. NEW JERSEY INSTITUTE FOR SUCCESSFUL AGING [UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY: "Ongoing Research on Aging in New Jersey (ORANJ BOWL)." "ORANJ BOWL is a survey research program where participants are assessed annually for many years. The goal of the research is to learn what determines who ages successfully and healthfully while understanding reasons for any differences that might exist between groups of people." For more information about the data file, go to:

To view a copy of the questionnaire, go to:

For more information about the project:


II. Reports and articles:


A. "International Update, July 2008" (July 2008, HTML and .pdf format, 2p.).

B. "SSI Monthly Statistics: June 2008 (July 2008, HTML and .pdf format).



A. "Defined Benefit Pensions: Plan Freezes Affect Millions of Participants and May Pose Retirement Income Challenges," (GAO-08-817, July 2008, .pdf format, 57p.).

B. "Long-Term Care Insurance: Oversight of Rate Setting and Claims Settlement Practices," (GAO-08-712, June 2008, .pdf format, 35p.).


6. BUREAU OF LABOR STATISTICS REPORT: "BLS Spotlight on Statistics: Older Workers," (July 2008, .pdf, HTML, and MP3 format, 10p.).


7. US DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF INSPECTOR GENERAL REPORT: "Early Implementation Review of Qualified Independent Contractor Processing of Medicare Appeal Reconsiderations," (OEI-06-06-00500, July 2008, .pdf format, 26p.).


In this final report, OIG found that, from May 2005 to July 2006, Qualified Independent Contractors (QIC) handling Medicare Part A claims reconsiderations met 60-day processing requirements. However, QICs handling Medicare Part B reconsiderations did not meet processing timeframes for 58 percent of reconsiderations. Further, the four QICs did not follow all requirements relating to correspondence, such as letters acknowledging appeal requests, notifications of the reconsideration decision, and notifications of any processing delays. We also found that for 54 percent of reconsiderations, QICs did not enter accurate information in the Medicare Appeals System, which stores reconsideration data and is used by CMS to monitor QIC adherence to processing requirements. QICs had not been operational for long at the time of our review, and CMS has since made several changes to improve the reconsiderations process. However, given the deficiencies we found and their potential impact on the Medicare appeals process, we recommend that CMS take further action to ensure that QICs meet timeliness, correspondence, and data entry requirements. CMS concurred with our recommendation.


8. INTERNATIONAL LONGEVITY CENTRE [UK] REPORT: "National Care Fund: Supplementary Paper One," by James Lloyd (July 2008, .pdf format, 17p.).



A. "New Research: By 2060 - Average Aussie Woman Will Reach 90 Years," (July 2008, .pdf and HTML format, 2p.).

B. "Study Reveals Benefit of Community Care Programs," (July 2008, .pdf and HTML format, 2p.).

C. "Improving Aged and Community Care for Indigenous Australians," (July 2008, .pdf and HTML format, 1p.).



A. "Sources of Income for Older Persons," by Ke Bin Wu (July 2008, .pdf format, 8p.).

B. The following Prime Time Radio show (RealPlayer format, running time, between 23 and 30 minutes) has been added to the PTR site:

Why So Many Ninety-Year-Olds?: Jul. 22, 2008.

Note: this is a temporary address. When new PTR shows are released, these will be available at:


11. HUDSON INSTITUTE REPORT: "Union vs. Private Sector Pensions: How Secure Are Union Members Retirements?" by Diana Furchtgott-Roth (July 2008, .pdf format, 51p.).

More information about Hudson Institute


12. AMERICAN ENTERPRISE INSTITUTE REPORT: "The Social Security Earnings Test: The Tax That Wasn't," by Andrew G. Biggs (Tax Policy Outlook, No. 3, July 2008, .pdf and HTML format, 4p.).


13. FAMILY CAREGIVER ALLIANCE NEWSLETTER: Caregiving Policy Digest (Vol. VIII, No. 15, July 23, 2008).



A. "Secular trends in self reported sexual activity and satisfaction in Swedish 70 year olds: cross sectional survey of four populations, 1971-2001," by Nils Beckman, Margda Waern, Deborah Gustafson, and Ingmar Skoog (Article Abstract, BMJ 2008;337:a279).

B. "Sexuality and older people," by Peggy J. Kleinplatz (Editorial Extract, BMJ 2008;337:a239).


15. LANCET ARTICLE ABSTRACTS: Note: Lancet requires free registration prior to providing content.

A. "Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study," by Prof. Rachelle S. Doody, Prof. Svetlana I. Gavrilova, Prof. Mary Sano, Prof. Ronald G. Thomas, Prof. Paul S. Aisen, Prof. Sergey O. Bachurin, Lynn Seely, and David Hung, on behalf of the dimebon investigators (Vol. 372, No. 9634, July 19, 2008, p. 207-215).

B. "Long-term effects of A-{beta}42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial," by Prof. Clive Holmes, Delphine Boche, David Wilkinson, Ghasem Yadegarfar, Vivienne Hopkins, Anthony Bayer, Prof. Roy W Jones, Roger Bullock, Prof. Seth Love, James W. Neal, Elina Zotova, and Prof. James A. R. Nicoll (Vol. 372, No. 9634, July 19, 2008, p. 216-223).



A. "Age-Specific Epigenetic Drift in Late-Onset Alzheimer's Disease," by Sun-Chong Wang, Beatrice Oelze, and Axel Schumacher (PLoS ONE 3(7): e2698 doi:10.1371/journal.pone.0002698, HTML, XML, and .pdf format 11p.).

B. "Mitochondrial Ca2+ Overload Underlies A-{beta} Oligomers Neurotoxicity Providing an Unexpected Mechanism of Neuroprotection by NSAIDs," by Sara Sanz-Blasco, Ruth A. Valero, Ignacio Rodruez-Crespo, Carlos Villalobos, and Luc Nez (PLoS ONE 3(7): e2718. doi:10.1371/journal.pone.0002718, HTML , XML, and .pdf format, 16p.).

C. "iTRAQ Analysis of Complex Proteome Alterations in 3xTgAD Alzheimer's Mice: Understanding the Interface between Physiology and Disease," by Bronwen Martin, Randall Brenneman, Kevin G. Becker, Marjan Gucek, Robert N. Cole, and Stuart Maudsley (PLoS ONE 3(7): e2750. doi:10.1371/journal.pone.0002750, HTML , XML, and .pdf format, 21p.).

D. "Impairment of Adolescent Hippocampal Plasticity in a Mouse Model for Alzheimer's Disease Precedes Disease Phenotype," by Daniela Hartl, Michael Rohe, Lei Mao, Matthias Staufenbiel, Claus Zabel, and Joachim Klose (PLoS ONE 3(7): e2759. doi:10.1371/journal.pone.0002759, HTML , XML, and .pdf format, 10p.).


17. NATURE LETTER ABSTRACT: "Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells," by Morgan E. Carlson, Michael Hsu, and Irina M. Conboy (Vol. 454, No. 7203, July 23, 2008, .p. 528-532).


18. ECONOMIST ARTICLE: "Capital Thinking: A call to set up a sovereign-wealth fund," (July 24, 2008).


III. Working Papers:

19. NATIONAL BUREAU OF ECONOMIC RESEARCH: "The Evolutionary Theory of Time Preferences and Intergenerational Transfers," by C.Y. Cyrus Chu, Hung-Ken Chien, and Ronald D. Lee (w14185, July 2008, .pdf format, 38p.).


At each age an organism produces energy by foraging and allocates this energy among reproduction, survival, growth, and intergenerational transfers. We characterize the optimal set of allocation decisions that maximizes reproductive fitness. Time preference (the discount rate) is derived from the marginal rate of substitution between energy obtained at two different times or ages in an individuals life, holding reproductive fitness constant. We show that the life history may have an initial immature phase during which there is body growth but no fertility, and a later mature phase with fertility but no growth, as with humans. During the immature phase, time preference depends only on the compounding effect of body growth, much like returns on a capital investment, but not on fertility, or the intrinsic population growth rate. During the mature phase, time preference depends on the costliness of fertility, and on endogenous survival and intrinsic growth rate, and not at all on body growth. During the transition between the two phases, fertility, mortality, body growth, and intrinsic growth rate all matter. Using these results, we conclude that time preference and discount rates are likely to be U-shaped across age. We compare our results to Hansson and Stuart (1990), Rogers (1994, 1997) and Sozou and Seymour (2003). Wastage and inefficiencies aside, in a single sex model a system of intergenerational transfers yields Samuelsons (1958) biological interest rate equal to the population growth rate. When the rate of time preference exceeds this biological rate, inter- generational transfers will raise fitness and evolve through natural selection, partially smoothing out the age variations in time preference.


20. URBAN INSTITUTE: "Will Employers Want Aging Boomers?" by Gordon Mermin, Richard W. Johnson, and Eric Toder (Discussion Paper 08-04, July 2008, .pdf format, 57p.). Links to the abstract and full-text can be found at:


21. RAND CORPORATION: "Retirement Effects on Health in Europe," by Norma B. Coe and Gema Zamarro (WR-588, June 2008, .pdf format, 36p.). Links to the abstract and full-text can be found at:


22. CENTER FOR ECONOMIC STUDIES/IFO INSTITUTE FOR ECONOMIC RESEARCH (CESifo) [MUNICH, BAVARIA, GERMANY]: "Alternative Social Security Systems and Growth," by Michael Kaganovich and Itzhak Zilcha (CESifo Working Paper No. 2353, July 2008, .pdf format, 36p.). Links to the abstract and full-text can be found at:


IV. Journal Tables of Contents (check your library for availability):

23. American Journal of Epidemiology (Vol. 168, No. 3, Aug. 1, 2008).

24. Journal of Applied Gerontology (Vol. 27, No. 4, August 2008). Note: Full text of this journal is available in the ProQuest Research Library and the EBSCO Host Academic Search Elite Database. Check your library for availability of these databases and this issue.

25. Medical Care Research and Review (Vol. 65, No. 4, August 2008). Note: Full electronic text of this journal is available in the ProQuest Research Library. Check your library for the availability of this database and this issue.


26. AMEDEO MEDICAL LITERATURE: Note: "AMEDEO has been created to serve the needs of healthcare professionals, including physicians, nurses, pharmacists, administrators, other members of the health professions, and patients and their friends. They can easily access timely, relevant information within their respective fields... All AMEDEO services are free of charge. This policy was made possible thanks to generous unrestricted educational grants provided by AMGEN, Berlex, Eisai, Glaxo Wellcome, Novartis, Pfizer, Roche, and Schering AG."

A. Osteoporosis: Literature for the week of July 23, 2008:

B. Alzheimer's Disease: Literature for the week of July 23, 2008:

C. Parkinson's Disease: Literature for the week of July 23, 2008:

D. Prostate Cancer: Literature for the week of July 23, 2008:

E. Stem Cell Research: Literature for the week of July 23, 2008:

F. Ophthalmology: Literature for the week of July 23, 2008:

AMEDEO Literature Guide:


V. Funding Opportunities:


A. "Implementation Planning Grants for Educational, Behavioral, or Social Studies for Translation of Genetic Factors in Common Diseases (U34)," (RFA-DK-08-003, National Institute on Aging, in conjunction with other agencies, July 16, 2008).

B. "Translation of Common Disease Genetics into Clinical Applications (R21)," (RFA-DK-08-004, National Institute on Aging, in conjunction with other agencies, July 16, 2008).

C. "Methodology and Measurement in the Behavioral and Social Sciences (R01)" (PAR-08-212, reissue of PA-07-060, National Institute on Aging, in conjunction with several other agencies, Jul. 22, 2008).

D. "Methodology and Measurement in the Behavioral and Social Sciences (R21)," (PAR-08-213, reissue of PA-06-343, National Institute on Aging, in conjunction with several other agencies, Jul. 22, 2008). For more information see:

E. "Methodology and Measurement in the Behavioral and Social Sciences (R03)" (PAR-08-214, reissue of PA-06-344, National Institute on Aging, in conjunction with several other agencies, Jul. 22, 2008). For more information see:

F. "Neural and Behavioral Profiles of Cognitive Aging (R01)," (RFA-AG-09-010, National Institute of Aging, July 23, 2008).


VI. Conferences:

28. US NATIONAL CENTER FOR HEALTH STATISTICS: "NCHS Data Users Conference," to be held on Aug. 11-13, 2008 in Washington, DC. For more information see:


VII. Legislation Information Updates:

29. US HOUSE COMMITTEE ON OVERSIGHT AND GOVERNMENT REFORM HEARING TESTIMONY: "The Medicare Drug Benefit: Are Private Insurers Getting Good Discounts for the Taxpayer?" a hearing held on July 24, 2008 (.pdf format).


30. US SENATE SPECIAL COMMITTEE ON AGING HEARING TESTIMONY: "Person-Centered Care: Reforming Services and Bringing Older Citizens Back to the Heart of Society," a hearing held July 23, 2008 (.pdf format).


VIII. Websites of Interest:

31. US SOCIAL SECURITY ADMINISTRATION: "Retirement Calculator," (July 2008). "The Retirement Estimator produces estimates that are based on your actual Social Security earnings record."




Charlie Fiss
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Phone: (608) 265-9240
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