Current Awareness in Aging Research (CAAR) Report #330--March 23, 2006


CAAR (Current Awareness in Aging Research) is a weekly email report produced by the Center for Demography of Health and Aging at the University of Wisconsin-Madison that helps researchers keep up to date with the latest developments in the field. For more information, including an archive of back issues and subscription information see:


I. Data:

1. US NATIONAL CENTER FOR HEALTH STATISTICS: "National Health Interview Survey Update." NCHS has released the Injury Episode File and Injury Verbatim File from the 2004 NHIS (self decompressing (.exe) ASCII data, documentation in .pdf format, and SAS, SPSS, and STATA statements in ASCII text format).

Scroll to "Injury Episode File" and/or "Injury Verbatim File".

2. INTER-UNIVERSITY CONSORTIUM FOR POLITICAL AND SOCIAL RESEARCH: ICPSR at the University of Michigan released several new datasets on Mar. 23, 2006, which may be of interest to researchers in aging. Note: Some ICPSR studies are available only to ICPSR member institutions. To find out whether your organization is a member, and whether or not it supports ICPSR Direct downloading, see:

New data:

All new and updated data in the last 90 days can be found at:

Click on "list".


II. Reports and articles:


A. "Defined Contribution Pension Plans and the Supplemental Security Income Program," by Rene Parent (Policy Brief No.2006-01, March 2006, .pdf and HTML format, 5p.).



B. "OASDI (Old-Age and Survivors Insurance and Disability Insurance) Monthly Statistics, February 2006," (March 2006, .pdf and HTML format).

C. "SSI (Supplementary Security Income) Monthly Statistics, February 2006," (March 2006, .pdf and HTML format).

4. U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF THE ASSISTANT SECRETARY FOR PLANNING AND EVALUATION, REPORT: "Pilot Long-Term Care Awareness Campaign: Phase I Final Report," (February 2006, .pdf and HTML format, 40p.).

5. U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF INSPECTOR GENERAL REPORT: "Medicares Program Safeguard Contractors: Performance Evaluation Reports," (OEI-03-04-00050, March 2006, .pdf format, 30p.).


OIG found that performance evaluation reports issued by CMS contained minimal information about program safeguard contractor (PSC) achievements related to detecting and deterring fraud and abuse under benefit integrity task orders. Because these reports have limited descriptions of the results PSCs may be achieving, they provide limited information on which to base task order renewal decisions. OIG also found 72 percent of performance evaluation reports for the period 1999-2004 were issued on time. However, only 5 of 32 final reports were issued 3 months before the task order ended. It is at this time that CMS is required to notify the PSC whether CMS intends to renew the contract. The unavailability of milestone dates prevented OIG from identifying where delays occurred in the evaluation process.

OIG recommended that CMS address PSC results in their performance evaluation reports and include quantitative as well as qualitative information; include information about required fraud and abuse detection and deterrence activities in the reports; ensure that all draft and final reports are issued on time; and establish a means to track and save evaluation milestone dates. CMS concurred with the last two recommendations. With regard to the first recommendation, CMS concurred in part. CMS believes that quantifying PSC outcomes may compromise investigations and create perverse incentives. OIG is not advocating a system of numeric quotas, but OIG does believe evaluation reports should include the level of activity and results that PSCs have achieved in combating fraud and abuse. With regard to the second recommendation, CMS stated that resources sometimes limit the level and intensity of scrutiny it can give to all PSC activities. OIG believes that activities required in PSC task orders should be addressed in evaluation reports.

6. MEDICAL EXPENDITURE PANEL SURVEY STATISTICAL BRIEF: "Out-of-Pocket Expenditures on Health Care and Insurance Premiums among the Elderly Population, 2003," by Jessica Banthin and Didem Bernard (Agency for Healthcare Research and Quality, Statistical Brief 122, March 2006, .pdf format, 6p.).


A. "Decision Memo for Microvolt T-wave Alternans (CAG-00293N)," (March 21, 2006).

B. "Decision Memo for External Counterpulsation (ECP) Therapy (CAG-00002R2)," (March 20, 2006).

C. "Decision Memo for Home Use of Oxygen (CAG-00296N)," (March 20, 2006).

D. "Decision Memo for Cardiac Rehabilitation Programs (CAG-00089R)," (March 22, 2006).

8. NATIONAL INSTITUTES OF HEALTH NEWS RELEASE: "Older Hispanics Can Prevent High Blood Pressure," (March 21, 2006).

9. DEPARTMENT OF WORK AND PENSIONS [UK] REPORT: "Pensioners' Incomes Series 2004/05," edited by Stephen Balchin and David Finch (March 2006, .pdf format, 95p.).

10. SCOTTISH EXECUTIVE REPORT: "Care Homes, Scotland September 2005," (March 2006, .pdf format, 21p.).

11. STATISTICS CANADA ARTICLE: "Employer pension plans (trusteed pension funds)," (_The Daily_, March 23, 2006).

12. ORGANISATION FOR ECONOMIC COOPERATION AND DEVELOPMENT GUIDELINES STATEMENT: " OECD Guidelines on Pensions Fund Asset Management," (March 2006, .pdf format, 14p.). A link to the full-text of the guidelines is available from the press release ("OECD calls for new approach to managing pension fund assets").,2340,en_2649_37435_36333268_1_1_1_37435,00.html

Link to full-text is at the end of the press release.


A. "Learning from Abroad: Lessons and Questions on Personal Health Records for National Policy," by Don Detmer and Elaine Steen (2006-10, March 2006, .pdf format, 67p.).

B. The following AARP _Prime Time Radio_ show is now available (RealPlayer plug-in or helper application required, audio transcripts run between 24 and 30 minutes).

Elder Care the Aussie Way

14. _NATURE_ LETTER ABSTRACT: "The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-{beta} production," by Lucia Pastorino, Anyang Sun, Pei-Jung Lu, Xiao Zhen Zhou, Martin Balastik, Greg Finn, Gerburg Wulf, Jormay Lim, Shi-Hua Li, Xiaojiang Li, Weiming Xia, Linda K. Nicholson and Kun Ping Lu (Vol. 440, No. 7083, March 23, 2006, p. 528-534).


A. "Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1," by Chittaranjan Das, Quyen Q. Hoang, Cheryl A. Kreinbring, Sarah J. Luchansky, Robin K. Meray, Soumya S. Ray, Peter T. Lansbury, Dagmar Ringe, and Gregory A. Petsko (Vol. 103, No. 12, March 21, 2006, p. 4675-4680).

B. "Somatic gene transfer of cAMP response element-binding protein attenuates memory impairment in aging rats," by Alexandre Mouravlev, Jane Dunning, Deborah Young, and Matthew J. During (Vol. 103, No. 12, March 21, 2006, .pdf and HTML format, p. 4705-4710). Note: _PNAS_ is providing free access to this article.

C. "Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts," by Je-Tae Woo, Makoto Kawatani, Masanori Kato, Toshimasa Shinki, Takayuki Yonezawa, Naoki Kanoh, Hiroshi Nakagawa, Masamichi Takami, Kun Hyung Lee, Paula H. Stern, Kazuo Nagai, and Hiroyuki Osada (Vol. 103, No. 12, March 21, 2006, p. 4729-4734).


A. "Applicability to primary care of national clinical guidelines on blood pressure lowering for people with stroke: cross sectional study," by Jonathan Mant, Richard J. McManus, and Rachel Hare (Vol. 332, No. 7542, March 18, 2006, .pdf and HTML format, p. 635-637).

B. "Osteoarthritis," by David J. Hunter and David T. Felson (Vol. 332, No. 7542, March 18, 2006, .pdf and HTML format, p. 639-642).

17. _JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION_ ARTICLE ABSTRACT: "Association of Physical Activity and Body Mass Index With Novel and Traditional Cardiovascular Biomarkers in Women," by Samia Mora, I-Min Lee, Julie E. Buring, and Paul M Ridker (Vol. 295, No. 12, March 22/29, 2006, p. 1412-1419).

18. ALZHEIMER'S DISEASE EDUCATION AND REFERRAL CENTER [ADEAR] NEWSLETTER: "Connections," (Vol. 13, No. 3/4, 2006, .pdf and HTML format, 12p.).

19. ILCUSA REPORT: "ILC Policy Report," (International Longevity Center, USA, March 2006, .pdf format, 6p.). The ILC Policy Report is "a monthly compilation of longevity news and trends in the U.S. and abroad."

20. _FORBES_ ARTICLE: "Sharp As A Tack," by Kerry A. Dolan (March 27, 2006).

21. _NEWSWEEK_ ARTICLE: "Autopilot for Retirement," by Jane Bryant Quinn (March 27, 2006).


III. Working Papers:

22. PRINCETON UNIVERSITY OFFICE OF POPULATION RESEARCH: "Physiological Dysregulation Predicted Poorer Health and Lower Survival in a Survey of the Older Population," by Noreen Goldman, Cassio M. Turra, Dana A. Glei, Yu-Hsuan Lin, and Maxine Weinstein (Working Paper 2006-03, March 2006, .pdf format, 24p.).


Objective: We investigate whether a multi-system measure of physiological dysregulation based on 16 biological measures is associated with deterioration in physical and mental health over a three-year period.

Study Design and Setting: We use data from a national survey of persons 54 and older in Taiwan that collected standard clinical markers related to cardiovascular and metabolic function and 'preclinical' measures pertaining to the immune, neuroendocrine and sympathetic nervous systems. The dysregulation score counts the number of biomarkers for which values are in the lowest or highest decile. Statistical models examine whether dysregulation predicts four health outcomes (survival, physical functioning, cognitive functioning and depressive symptoms), in the presence of extensive controls for baseline health.

Results: The estimates reveal significant associations between dysregulation and health for each outcome, although there is variability across outcomes. The associations are often attenuated in the presence of health controls, underscoring the importance of longitudinal analysis.

Conclusion: This study has extended previous research on the health consequences of physiological dysregulation by considering a broader range of outcomes and biomarkers in a non-Western population-based sample. Our analysis suggests that such dysregulation provides early warning signs of a broad range of co-morbidities.

23. NATIONAL BUREAU OF ECONOMIC RESEARCH: "The Impact of Antihypertensive Drugs on the Number and Risk of Death, Stroke and Myocardial Infarction in the United States," by Genia Long, David Cutler, Ernst R. Berndt, Jimmy Royer, Andree-Anne Fournier, Alicia Sasser, and Pierre Cremieux (Working Paper No. w12096, March 2006, .pdf format, 25p.).


Estimating the value of medical innovation is a continual challenge. In this research, we quantify the impact of antihypertensive therapy on U.S. blood pressures, risk and number of heart attacks, strokes, and deaths. We also consider the potential for further improvements. We estimate the value of innovation using equations relating blood pressure to adverse outcomes from the Framingham Heart Study. Our results show that without antihypertensive therapy, 1999-2000 average blood pressure for the U.S. population age 40 plus would have been 10-13 percent higher. 86,000 excess premature deaths from cardiovascular disease (2001), and 833,000 hospital discharges for stroke and heart attacks (2002) would have occurred. Life expectancy would be 0.5 (men) and 0.4 (women) years lower. At guideline care, there would have been 89,000 fewer premature deaths (2001) and 420,000 fewer hospital discharges for stroke and heart attack (2002) than observed. Our analysis suggests that antihypertensive therapy has had a significant impact on cardiovascular health outcomes but that mortality gains would have been approximately twice as high if guideline care had been achieved for all.

24. INSTITUTE FOR THE STUDY OF LABOR (IZA) [UNIVERSITY OF BONN, GERMANY]: "The Time and Timing Costs of Market Work, and their Implications for Retirement," by Daniel S. Hamermesh (Discussion Paper No. 2030, March 2006, .pdf format, 23p.).


Retirement ages among older Americans have only recently begun to increase after a precipitous fifty-year decline. Early retirement may result from incentives provided by retirement systems; but it may also result from the rigidities imposed by market work schedules. Using the American Time Use Survey of 2003 and 2004, I first examine whether additional market work is neutral with respect to the mix of non-market activities. The estimates indicate that there are fixed time costs of remaining in the labor market that alter the pattern of non-market activities, reducing leisure time and mostly increasing time devoted to household production. Market work also alters the timing of a fixed amount of non-market activities during the day, away from the schedule chosen when timing constraints imposed by market work do not exist. All of these effects are mitigated by higher family income, presumably because higher-income people can purchase market substitutes that enable them to overcome the fixed time costs of market work.

25. FEDERAL RESERVE BANK OF BOSTON: "Pension Accounting and Corporate Earnings: The World According to GAAP," by Peter Fortune (Public Policy Discussion Paper No. 06-1, March 2006, .pdf format, 48p.).


IV. Journal Tables of Contents (check your library for availability):

26. American Journal of Epidemiology (Vol. 163, No. 7, April 1, 2006).

27. American Journal of Public Health (Vol. 96, No. 4, April 2006). Note: Full electronic text of this journal is available in the ProQuest Research Library and the EBSCO Host Academic Search Elite database. Check your library for the availability of this database and this issue.

28. European Journal of Palliative Care (Vol. 13, No. 2, 2006).

29. Health Economics, Policy and Law (Vol. 1, No. 2, April 2006).

30. Omega (Vol. 52, No. 1, 2006).

31. AMEDEO MEDICAL LITERATURE: Note: "AMEDEO has been created to serve the needs of healthcare professionals, including physicians, nurses, pharmacists, administrators, other members of the health professions, and patients and their friends. They can easily access timely, relevant information within their respective fields... All AMEDEO services are free of charge. This policy was made possible thanks to generous unrestricted educational grants provided by AMGEN, Berlex, Eisai, Glaxo Wellcome, Novartis, Pfizer, Roche, and Schering AG."

A. Osteoporosis: Literature for the week of March 22, 2006:

B. Alzheimer's Disease: Literature for the week of March 22, 2006:

C. Parkinson's Disease: Literature for the week of March 22, 2006:

D. Prostate Cancer: Literature for the week of March 22, 2006:

E. Stem Cell Research: Literature for the week of March 22, 2006:

F. Ophthalmology: Literature for the week of March 22, 2006:

AMEDEO Literature Guide:


V. Books:

32. SPRINGER PUBLISHING: _The Aging Network: Programs and Services_ by Donald E. Gelfand (Sixth Edition, February 2006, 264p., ISBN: 0826102069, $35.00).

33. NATIONAL ACADEMY PRESS: _Medicare's Quality Improvement Organization Program: Maximizing Potential_ (Committee on Redesigning Health Insurance Performance Measures, Payment, and Performance Improvement Programs, 2006, OpenBook format, ~500p.).

34. INSTITU NATIONAL D'ETUDES DEMOGRAPHIQUES: _Human Clocks: The Bio-Cultural Meanings of Age_ by Claudine Sauvain-Dugerdil, Henri Leridon and Nicholas Mascie-Taylor (is in Vol. 5 of Population, Family, and Society, 2006, ISBN 3-03910-785-2, 349p.). Note: Ordering information is available at:


VI. Funding Opportunities:

35. NIH:

A. "The Secretory Pattern of Senescent Cells (R21)," (US National Institutes of Health, National Institute on Aging, in conjunction with other agencies, PA-06-138, March 17, 2006).

B. "Ancillary Studies to the AD Neuroimaging Initiative (R03)," (US National Institutes of Health, National Institute on Aging, in conjunction with other agencies, PA-06-240, March 17, 2006).

C. "Ancillary Studies to the AD Neuroimaging Initiative (R21)," (US National Institutes of Health, National Institute on Aging, in conjunction with other agencies, PA-06-241, March 17, 2006).

D. "Aging Musculoskeletal and Skin Extracellular Matrix (R21)," (US National Institutes of Health, National Institute on Aging, in conjunction with other agencies, PA-06-242, March 17, 2006).

E. "Basic Research in the Bladder and Lower Urinary Tract (R01)," (US National Institutes of Health, National Institute on Aging, in conjunction with other agencies, PA-06-254, March 17, 2006).

F. "Basic Research in the Bladder and Lower Urinary Tract (R21)," (US National Institutes of Health, National Institute on Aging, in conjunction with other agencies, PA-06-255, March 17, 2006).

36. NATIONAL HEALTH AND MEDICAL RESEARCH COUNCIL [AUSTRALIA]: "Dementia Research Grants," (March 2006). "The implementation of the Dementia Research Grants Program is a joint project between the Ageing and Aged Care Division of the Department of Health and Ageing and the National Health and Medical Research Council (NHMRC). The program is part of the Australian Government's Helping Australians with dementia and their carers- making dementia a National Health Priority initiative." The deadline for application is May 11, 2006.


VII. Conferences:

37. MINNESOTA POPULATION CENTER [UNIVERSITY OF MINNESOTA]: "IPUMS Summer Workshop," to be held July 19-21, 2006 (University of Minnesota, Twin Cities). "The IPUMS Summer Workshop is a 3-day event designed to train social scientists to use the Integrated Public Use Microdata Series. The databases covered will include IPUMS-USA, IPUMS-International, IPUMS-CPS and the North Atlantic Population Project. Together, these databases cover 150 years of U.S. and international census data."

38. EUROPEAN GROUP FOR RESEARCH INTO ELDERLY AND PHYSICAL ACTIVITY: "Physical Activity And Successful Aging: Xth International Conference," to be held September 14-16, 2006 (Cologne, Germany).


VIII. Legislation Information Updates:

39. US HOUSE COMMITTEE ON THE JUDICIARY, SUBCOMMITTEE ON COMMERCIAL AND ADMINISTRATIVE LAW, HEARING PUBLICATION: "To Amend Title 4 of the United States Code to Clarify the Treatment of Self-Employment for Purposes of the Limitation on State Taxation of Retirement Income, on H.R. 4019," a hearing held December 13, 2005 (Serial No. 109-72, .pdf and ASCII text format, 29p.).

Search on "109-72" (without the quotes).

40. US SENATE COMMITTEE ON APPROPRIATIONS HEARING PUBLICATION: "Stem Cells Research, 2005," a special hearing held October 19, 2005 (S.Hrg.109-249, .pdf and ASCII format, 25p.).

Search on "109-249" (without the quotes).


IX. Websites of Interest:

41. KAISER FAMILY FOUNDATION TUTORIAL: "Medicare/Medicaid Dual Eligibles Tutorial," by Linda Elam (March 2006, Power Point format, running time 15:55).




Charlie Fiss
Information Manager
Center for Demography and Ecology and
Center for Demography of Health and Aging
Rm. 4470A Social Science Bldg
1180 Observatory Drive
Madison, WI 53706-1393
Phone: (608) 265-9240
Fax: (608) 262-8400