CDHA CAAR

August 22, 2017

CAAR – Proceedings of the National Academy of Sciences Article Abstracts – August 22, 2017

A. “Identification of the Tau phosphorylation pattern that drives its aggregation,” by Clement Despres, Cillian Byrne, Haoling Qi, Francois-Xavier Cantrelle, Isabelle Huvent, Beatrice Chambraud, Etienne-Emile Baulieu, Yves Jacquot, Isabelle Landrieu, Guy Lippens, and Caroline Smet-Nocca (Vol. 114, No. 34, August 22, 2017, p. 9080-9085).

www.pnas.org/content/114/34/9080.abstract.html?etoc

B. “MicroRNA-mediated disruption of dendritogenesis during a critical period of development influences cognitive capacity later in life,” by Quan Lin, Ravikumar Ponnusamy, Jocelyn Widagdo, Jung A. Choi, Weihong Ge, Christine Probst, Tyler Buckley, Mimi Lou, Timothy W. Bredy, Michael S. Fanselow, Keqiang Ye, and Yi E. Sun (Vol. 114, No. 34, August 22, 2017, p. 9188–9193).

www.pnas.org/content/114/34/9188.abstract.html?etoc

July 12, 2017

CAAR – Nature Article Abstract – July 12, 2017

Filed under: Reports and Articles — Tags: , — admin @ 4:49 pm

Cryo-EM structures of tau filaments from Alzheimer’s disease,” by Anthony W. P. Fitzpatrick, Benjamin Falcon, Shaoda He, Holly J. Garringer, R. Anthony Crowther, Bernardino Ghetti, Michel Goedert & Sjors H. W. Scheres (Vol. 547, No. 7662, July 12, 2017, p. 185-190).

www.nature.com/nature/journal/v547/n7662/abs/nature23002.html

June 2, 2017

CAAR – Public Library of Science (PLoS) Article – June 2, 2017

Filed under: Reports and Articles — Tags: , — admin @ 5:03 pm

Bacterial co-expression of human Tau protein with protein kinase A and 14-3-3 for studies of 14-3-3/phospho-Tau interaction,” by Kristina V. Tugaeva, Philipp O. Tsvetkov, and Nikolai N. Sluchanko (PLoS ONE 12(6): e0178933. doi.org/10.1371/journal.pone.0178933, XML, HTML, and .pdf format, p.).

journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0178933

May 11, 2017

CAAR – Lancet Neurology Article Abstract – May 11, 2017

Filed under: Reports and Articles — Tags: , , — admin @ 5:18 pm

Age-specific and sex-specific prevalence of cerebral {beta}-amyloidosis, tauopathy, and neurodegeneration in cognitively unimpaired individuals aged 50–95 years: a cross-sectional study,” by Clifford R. Jack Jr., Heather J. Wiste, Stephen D. Weigand, Terry M. Therneau, David S. Knopman, Val Lowe, Prashanthi Vemuri, Michelle M. Mielke, Rosebud O. Roberts, Mary M. Machulda, Matthew L. Senjem, Jeffrey L. Gunter, Walter A. Rocca, and Ronald C. Petersen (Vol. 16, No. 6, June 2017, p. 435-444).

www.thelancet.com/journals/laneur/article/PIIS1474-4422(17)30077-7/abstract

January 17, 2017

CAAR – Proceedings of the National Academy of Sciences Article Abstract – January 17, 2017

Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation,” by William A. McEwan, Benjamin Falcon, Marina Vaysburd, Dean Clift, Adrian L. Oblak, Bernardino Ghetti, Michel Goedert, and Leo C. James (Vol. 114, No. 3, January 17, 2017, p. 574-579).

www.pnas.org/content/114/3/574.abstract

November 18, 2016

CAAR – Science Letter Abstract – November 18, 2016

Filed under: Reports and Articles — Tags: , , , — admin @ 4:51 pm

Site-specific phosphorylation of tau inhibits amyloid-{beta} toxicity in Alzheimer’s mice,” by Arne Ittner, Sook Wern Chua, Josefine Bertz, Alexander Volkerling, Julia Van Der Hoven, Amadeus Gladbach, Magdalena Przybyla, Mian Bi, Annika Van Hummel, Claire H. Stevens, Stefania Ippati, Lisa S. Suh, Alexander Macmillan, Greg Sutherland, Jillian J. Kril, Ana P. G. Silva, Joel Mackay, Anne Poljak, Fabien Delerue, Yazi D. Ke, and Lars M. Ittner (Vol. 354, No. 6314, November 18, 2016, p. 904-908).

science.sciencemag.org/content/354/6314/904.abstract

November 8, 2016

CAAR – Nature Medicine Article Abstract – November 8, 2016

Filed under: Reports and Articles — Tags: , , — admin @ 5:03 pm

Caspase-2 cleavage of tau reversibly impairs memory,” by Xiaohui Zhao, Linda A. Kotilinek, Benjamin Smith, Chris Hlynialuk, Kathleen Zahs, Martin Ramsden, James Cleary & Karen H. Ashe (Vol. 22, No. 11, November 2016, p. 1268–1276).

www.nature.com/nm/journal/v22/n11/abs/nm.4199.html

July 26, 2016

CAAR – Nature Neuroscience Brief Communication, Article Abstract – July 26, 2016

Filed under: Reports and Articles — Tags: , , — admin @ 4:46 pm

A. “Age-related myelin degradation burdens the clearance function of microglia during aging,” by Shima Safaiyan, Nirmal Kannaiyan, Nicolas Snaidero, Simone Brioschi, Knut Biber, Simon Yona, Aimee L Edinger, Steffen Jung, Moritz J. Rossner & Mikael Simons (Vol. 19, No. 8, August 2016, p. 995-998).

www.nature.com/neuro/journal/v19/n8/abs/nn.4325.html

B. “Neuronal activity enhances tau propagation and tau pathology in vivo,” by Jessica W. Wu, S. Abid Hussaini, Isle M. Bastille, Gustavo A. Rodriguez, Ana Mrejeru, Kelly Rilett, David W. Sanders, Casey Cook, Hongjun Fu, Rick A. C. M. Boonen, Mathieu Herman, Eden Nahmani, Sheina Emrani, Y. Helen Figueroa, Marc I. Diamond, Catherine L. Clelland, Selina Wray & Karen E. Duff (Vol. 19, No. 8, August 2016, p. 1085-1092).

www.nature.com/neuro/journal/v19/n8/abs/nn.4328.html

June 29, 2016

CAAR – Public Library of Science (PLoS) Articles – June 29, 2016

Filed under: Reports and Articles — Tags: , , , — admin @ 4:56 pm

A. “Dynamic PET Measures of Tau Accumulation in Cognitively Normal Older Adults and Alzheimer’s Disease Patients Measured Using [18F] THK-5351,” by Samuel N. Lockhart, Suzanne L. Baker, Nobuyuki Okamura, Katsutoshi Furukawa, Aiko Ishiki, Shozo Furumoto, Manabu Tashiro, Kazuhiko Yanai, Hiroyuki Arai, Yukitsuka Kudo, Ryuichi Harada, Naoki Tomita, Kotaro Hiraoka, Shoichi Watanuki, and William J. Jagust (PLoS ONE 11(6): e0158460. doi:10.1371/journal.pone.0158460, XML, HTML, and .pdf format, 16p.).

journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0158460

B. “Barriers to Effective Postmenopausal Osteoporosis Treatment: A Qualitative Study of Patients’ and Practitioners’ Views,” by Sophie Alami, Lucile Hervouet, Serge Poiraudeau, Karine Briot, and Christian Roux (PLoS ONE 11(6): e0158365. doi:10.1371/journal.pone.0158365, XML, HTML, and .pdf format, 16p.).

journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0158365

June 28, 2016

CAAR – Proceedings of the National Academy of Sciences Article Abstracts – June 28, 2016

A. “Tau protein is essential for stress-induced brain pathology,” by Sofia Lopes, Joao Vaz-Silva, Vitor Pinto, Christina Dalla, Nikolaos Kokras, Benedikt Bedenk, Natalie Mack, Michael Czisch, Osborne F. X. Almeida, Nuno Sousa, and Ioannis Sotiropoulos (Vol. 113, No. 26, June 28, 2016, p. E3755-E3763).

www.pnas.org/content/113/26/E3755.abstract

B. “Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling,” by Yaling Yin, Di Gao, Yali Wang, Zhi-Hao Wang, Xin Wang, Jinwang Ye, Dongqin Wu, Lin Fang, Guilin Pi, Ying Yang, Xiao-Chuan Wang, Chengbiao Lu, Keqiang Ye, and Jian-Zhi Wang (Vol. 113, No. 26, June 28, 2016, p. E3773-E3781).

www.pnas.org/content/113/26/E3773.abstract

January 6, 2016

CAAR – Nature Medicine Article Abstracts – January 16, 2016

Filed under: Reports and Articles — Tags: , , — admin @ 4:19 pm

A. “Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling,” by Natura Myeku, Catherine L. Clelland, Sheina Emrani, Nikolay V. Kukushkin, Wai Haung Yu, Alfred L. Goldberg & Karen E. Duff (Vol. 22, No. 1, January 2016, p. 46-53).

www.nature.com/nm/journal/v22/n1/abs/nm.4011.html

B. “Parkinson’s disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes,” by Wenzhang Wang, Xinglong Wang, Hisashi Fujioka, Charles Hoppel, Alan L Whone, Maeve A. Caldwell, Peter J. Cullen, Jun Liu & Xiongwei Zhu (Vol. 22, No. 1, January 2016, p. 54-63).

www.nature.com/nm/journal/v22/n1/abs/nm.3983.html

January 4, 2016

CAAR – Public Library of Science (PLoS) Articles – January 4, 2016

Filed under: Reports and Articles — Tags: , , , , — admin @ 4:33 pm

A. “Using Human iPSC-Derived Neurons to Model TAU Aggregation,” by An Verheyen, Annick Diels, Joyce Dijkmans, Tutu Oyelami, Giulia Meneghello, Liesbeth Mertens, Sofie Versweyveld, Marianne Borgers, Arjan Buist, Pieter Peeters, and Miroslav Cik (PLoS ONE 10(12): e0146127. doi:10.1371/journal.pone.0146127, XML, HTML, and .pdf format, 15p.).

journals.plos.org/plosone/article?id=10.1371/journal.pone.0146127

B. “The Modified painDETECT Questionnaire for Patients with Hip or Knee Osteoarthritis: Translation into Dutch, Cross-Cultural,” by Wietske Rienstra, Tim Blikman, Frans B. Mensink, Jos J. A. M. van Raay, Baukje Dijkstra, Sjoerd K. Bulstra, Martin Stevens, and Inge van den Akker-Scheek (PLoS ONE 10(12): e0146117. doi:10.1371/journal.pone.0146117, XML, HTML, and .pdf format, 12p.).

journals.plos.org/plosone/article?id=10.1371/journal.pone.0146117

C. “The Relationship between Neuroticism, Hopelessness, and Depression in Older Korean Immigrants,” by Bum Jung Kim, Kristen Linton, Sean Cho, and Jung-Hwa Ha (PLoS ONE 11(1): e0145520. doi:10.1371/journal.pone.0145520, XML, HTML, and .pdf format, 10p.).

journals.plos.org/plosone/article?id=10.1371/journal.pone.0145520

November 24, 2015

CAAR – Proceedings of the National Academy of Sciences Article Abstract – November 24, 2015

Filed under: Reports and Articles — Tags: , — admin @ 5:02 pm

Direct force measurements reveal that protein Tau confers short-range attractions and isoform-dependent steric stabilization to microtubules,” by Peter J. Chung, Myung Chul Choi, Herbert P. Miller, H. Eric Feinstein, Uri Raviv, Youli Li, Leslie Wilson, Stuart C. Feinstein, and Cyrus R. Safinya (Vol. 112, No. 47, November 24, 2015, p. E6416–E6425).

www.pnas.org/content/112/47/E6416.abstract.html?etoc

October 7, 2015

CAAR – Nature Medicine Article Abstract – October 7, 2015

Filed under: Working Papers — Tags: , — admin @ 4:58 pm

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits,” by Sang-Won Min, Xu Chen, Tara E. Tracy, Yaqiao Li, Yungui Zhou, Chao Wang, Kotaro Shirakawa, S. Sakura Minami, Erwin Defensor, Sue Ann Mok, Peter Dongmin Sohn, Birgit Schilling, Xin Cong, Lisa Ellerby, Bradford W. Gibson, Jeffrey Johnson, Nevan Krogan, Mehrdad Shamloo, Jason Gestwicki, Eliezer Masliah, Eric Verdin & Li Gan (Vol. 21, No. 10, October 2015, p. 1154-1162).

www.nature.com/nm/journal/v21/n10/abs/nm.3951.html

July 29, 2015

CAAR -Nature Neuroscience Resource Abstract – July 29, 2015

Filed under: Reports and Articles — Tags: , — admin @ 5:00 pm

Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice,” by Meaghan Morris, Giselle M. Knudsen, Sumihiro Maeda, Jonathan C. Trinidad, Alexandra Ioanoviciu, Alma L. Burlingame & Lennart Mucke (Vol. 18, No. 8, August 2015, p. 1183-1189).

www.nature.com/neuro/journal/v18/n8/abs/nn.4067.html

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