“Brain Imaging of Vesicular Monoamine Transporter Type 2 in Healthy Aging Subjects by 18F-FP-(+)-DTBZ PET,” by Kun-Ju Lin, Yi-Hsin Weng, Chia-Ju Hsieh, Wey-Yil Lin, Shiaw-Pyng Wey, Mei-Ping Kung, Tzu-Chen Yen, Chin-Song Lu, and Ing-Tsung Hsiao (PLoS ONE 8(9): e75952. doi:10.1371/journal.pone.0075952, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0075952
“The ubiquitin ligase parkin mediates resistance to intracellular pathogens,” by Paolo S. Manzanillo, Janelle S. Ayres, Robert O. Watson, Angela C. Collins, Gianne Souza, Chris S. Rae, David S. Schneider, Ken Nakamura, Michael U. Shiloh & Jeffery S. Cox (Vol. 501, No. 7468, September 25, 2013, p. 512-516).
www.nature.com/nature/journal/v501/n7468/abs/nature12566.html
Journal of Aging & Social Policy (Vol. 25, No. 4, 2013).
www.tandfonline.com/toc/wasp20/current
Journal of Parkinson’s Disease (Vol. 3, No. 3, 2013).
A. “Motor Timing Deficits in Sequential Movements in Parkinson Disease Are Related to Action Planning: A Motor Imagery Study,” by Laura Avanzino, Elisa Pelosin, Davide Martino, and Giovanni Abbruzzese (PLoS ONE 8(9): e75454. doi:10.1371/journal.pone.0075454, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0075454
B. “Huperzine A for Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Randomized Clinical Trials,” by Guoyan Yang, Yuyi Wang, Jinzhou Tian, and Jian-Ping Liu (PLoS ONE 8(9): e74916. doi:10.1371/journal.pone.0074916, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0074916
C. “Age-Related Hearing Loss and the Factors Determining Continued Usage of Hearing Aids among Elderly Community-Dwelling Residents,” by Kunio Mizutari, Takehiro Michikawa, Hideyuki Saito, Yasuhide Okamoto, Chieko Enomoto, Toru Takebayashi, Kaoru Ogawa, and Yuji Nishiwaki (PLoS ONE 8(9): e73622. doi:10.1371/journal.pone.0073622, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0073756
A. “Integrated multidisciplinary care in Parkinson’s disease: a non-randomised, controlled trial (IMPACT),” by Marjolein A. van der Marck, Marten Munneke, Wim Mulleners, Edo M. Hoogerwaard, George F. Borm, Sebastiaan Overeem, Bastiaan R. Bloem, for the IMPACT study group (Vol 12, No. 10, October 2013, p. 947-956).
www.thelancet.com/journals/laneur/article/PIIS1474-4422(13)70196-0/abstract
B. “Preclinical Alzheimer’s disease and its outcome: a longitudinal cohort study,” by Stephanie J.B. Vos, Chengjie Xiong, Pieter Jelle Visser, Mateusz S. Jasielec, Jason Hassenstab, Elizabeth A. Grant, Nigel J. Cairns, John C. Morris, David M. Holtzman, and Anne M. Fagan(Vol 12, No. 10, October 2013, p. 957-965).
www.thelancet.com/journals/laneur/article/PIIS1474-4422(13)70194-7/abstract
A. “Cognitive Declines Precede and Predict Functional Declines in Aging and Alzheimer’s Disease,” by Laura B. Zahodne, Jennifer J. Manly, Anna MacKay-Brandt, and Yaakov Stern (PLoS ONE 8(9): e73645. doi:10.1371/journal.pone.0073645, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0073645
B. “Long-Term Effects of Statin Treatment in Elderly People: Extended Follow-Up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER),” by Suzanne M. Lloyd, David J. Stott, Anton J. M. de Craen, Patricia M. Kearney, Naveed Sattar, Ivan Perry, Christopher J. Packard, Andrew Briggs, Laura Marchbank, Harry Comber, J. Wouter Jukema, Rudi G. J. Westendorp, Stella Trompet, Brendan M. Buckley, and Ian Ford (PLoS ONE 8(9): e72642. doi:10.1371/journal.pone.0072642, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0072642
C. “Parkinson’s Disease Is Related to an Increased Risk of Ischemic Stroke-A Population-Based Propensity Score-Matched Follow-Up Study,” by Ya-Ping Huang, Li-Sheng Chen, Ming-Fang Yen, Ching-Yuan Fann, Yueh-Hsia Chiu, Hsiu-Hsi Chen, and Shin-Liang Pan (PLoS ONE 8(9): e68314. doi:10.1371/journal.pone.0068314, XML, HTML, and .pdf format, 6p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068314
D. “The Dopamine D3 Receptor Knockout Mouse Mimics Aging-Related Changes in Autonomic Function and Cardiac Fibrosis,” by Tracy L. Johnson, David A. Tulis, Benjamin E. Keeler, Jitka A. Virag, Robert M. Lust, and Stefan Clemens (PLoS ONE 8(8): e74116. doi:10.1371/journal.pone.0074116, XML, HTML, and .pdf format, 12p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0074116
“The Parkinson’s disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy,” by Victoria S. Burchell, David E. Nelson, Alvaro Sanchez-Martinez, Marta Delgado-Camprubi, Rachael M. Ivatt, Joe H. Pogson, Suzanne J. Randle, Selina Wray, Patrick A. Lewis, Henry Houlden, Andrey Y. Abramov, John Hardy, Nicholas W. Wood, Alexander J. Whitworth, Heike Laman & Helene Plun-Favreau (Vol. 16, No. 9, September 2013, p. 1257-1265).
A. “Elevated Alpha-Synuclein Impairs Innate Immune Cell Function and Provides a Potential Peripheral Biomarker for Parkinson’s Disease,” by Shyra J. Gardai, Wenxian Mao, Birgitt Schüle, Michael Babcock, Sue Schoebel, Carlos Lorenzana, Jeff Alexander, Sam Kim, Heather Glick, Kathryn Hilton, J. Kent Fitzgerald, Manuel Buttini, San-San Chiou, Lisa McConlogue, John P. Anderson, Dale B. Schenk, Frederique Bard, J. William Langston, Ted Yednock, and Jennifer A. Johnston (PLoS ONE 8(8): e71634. doi:10.1371/journal.pone.0071634, XML, HTML, and .pdf format, 21p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0071634
B. “Phototoxic Action Spectrum on a Retinal Pigment Epithelium Model of Age-Related Macular Degeneration Exposed to Sunlight Normalized Conditions,” by Emilie Arnault, Coralie Barrau, Celine Nanteau, Pauline Gondouin, Karine Bigot, Francoise Vienot, Emmanuel Gutman, Valerie Fontaine, Thierry Villette, Denis Cohen-Tannoudji, Jose-Alain Sahel, and Serge Picaud (PLoS ONE 8(8): e71398. doi:10.1371/journal.pone.0071398, XML, HTML, and .pdf format, 12p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0071398
A. “The Heterogeneity of Early Parkinson’s Disease: A Cluster Analysis on Newly Diagnosed Untreated Patients,” by Roberto Erro, Carmine Vitale, Marianna Amboni, Marina Picillo, Marcello Moccia, Katia Longo, Gabriella Santangelo, Anna De Rosa, Roberto Allocca, Flavio Giordano, Giuseppe Orefice, Giuseppe De Michele, Lucio Santoro, Maria Teresa Pellecchia, and Paolo Barone (PLoS ONE 8(8): e70244. doi:10.1371/journal.pone.0070244, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0070244
B. “Conformational Stability of Fibrillar Amyloid-Beta Oligomers via Protofilament Pair Formation – A Systematic Computational Study,” by Anna Kahler, Heinrich Sticht, Anselm H. C. Horn (PLoS ONE 8(7): e70521. doi:10.1371/journal.pone.0070521, XML, HTML, and .pdf format, 12p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0070521
C. “Defensive Effect of Lansoprazole in Dementia of AD Type in Mice Exposed to Streptozotocin and Cholesterol Enriched Diet,” by Rupinder K. Sodhi and Nirmal Singh (PLoS ONE 8(7): e70487. doi:10.1371/journal.pone.0070487, XML, HTML, and .pdf format, 10p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0070487
D. “Grasping the Changes Seen in Older Adults When Reaching for Objects of Varied Texture,” by Raymond J. Holt, Alexis S. Lefevre, Ian J. Flatters, Pete Culmer, Richard M. Wilkie, Brian W. Henson, Geoff P. Bingham, and Mark Mon-Williams (PLoS ONE 8(7): e69040. doi:10.1371/journal.pone.0069040, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069040
A. “Prevalence and Burden of Gait Disorders in Elderly Men and Women Aged 60-97 Years: A Population-Based Study,” by Philipp Mahlknecht, Stefan Kiechl, Bastiaan R. Bloem, Johann Willeit, Christoph Scherfler, Arno Gasperi, Gregorio Rungger, Werner Poewe, and Klaus Seppi (PLoS ONE 8(7): e69627. doi:10.1371/journal.pone.0069627, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069627
B. “Early Enriched Environment Exposure Protects Spatial Memory and Accelerates Amyloid Plaque Formation in APPSwe/PS1L166P Mice,” by Francesca Montarolo, Roberta Parolisi, Eriola Hoxha, Enrica Boda, and Filippo Tempia (PLoS ONE 8(7): e69381. doi:10.1371/journal.pone.0069381, XML, HTML, and .pdf format, 14p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069381
C. “High Glucose Promotes A{beta} Production by Inhibiting APP Degradation,” by Yi Yang, Yili Wu, Shuting Zhang, and Weihong Song (PLoS ONE 8(7): e69824. doi:10.1371/journal.pone.0069824, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069824
D. “Rotigotine Transdermal Patch in Parkinson’s Disease: A Systematic Review and Meta-Analysis,” by Chang-Qing Zhou, Shan-Shan Li, Zhong-Mei Chen, Feng-Qun Li, Peng Lei, and Guo-Guang Peng (PLoS ONE 8(7): e69738. doi:10.1371/journal.pone.0069738, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069738
E. “Dopaminergic Neuronal Imaging in Genetic Parkinson’s Disease: Insights into Pathogenesis,” by Alisdair McNeill, Ruey-Meei Wu, Kai-Yuan Tzen, Patricia C. Aguiar, Jose M. Arbelo, Paolo Barone, Kailash Bhatia, Orlando Barsottini, Vincenzo Bonifati, Sevasti Bostantjopoulou, Rodrigo Bressan, Giovanni Cossu, Pietro Cortelli, Andre Felicio, Henrique B. Ferraz, Joanna Herrera, Henry Houlden, Marcelo Hoexter, Concepcion Isla, Andrew Lees, Oswaldo Lorenzo-Betancor, Niccolo E. Mencacci, Pau Pastor, Sabina Pappata, Maria Teresa Pellecchia, Laura Silveria-Moriyama, Andrea Varrone, Tom Foltynie, and Anthony H. V. Schapira (PLoS ONE 8(7): e69190. doi:10.1371/journal.pone.0069190, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069190
F. “Glucose Metabolism during Resting State Reveals Abnormal Brain Networks Organization in the Alzheimer’s Disease and Mild Cognitive Impairment,” by Gretel Sanabria-Diaz, Eduardo Martínez-Montes, and Lester Melie-Garcia, the Alzheimer’s Disease Neuroimaging Initiative (PLoS ONE 8(7): e68860. doi:10.1371/journal.pone.0068860, XML, HTML, and .pdf format, 25p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068860
“Pramipexole in patients with early Parkinson’s disease (PROUD): a randomised delayed-start trial,” by Prof. Anthony H.V. Schapira, Prof. Michael P. McDermott, Prof. Paolo Barone, Prof Cynthia L. Comella, Stefan Albrecht, Helen H. Hsu, Daniel H. Massey, Prof. Yoshikuni Mizuno, Prof. Werner Poewe, Prof. Olivier Rascol, and Kenneth Marek (Vol. 12, No. 8, August 2013, p. 747-755).
www.thelancet.com/journals/laneur/article/PIIS1474-4422(13)70117-0/abstract
“Automated, High Accuracy Classification of Parkinsonian Disorders: A Pattern Recognition Approach,” by Andre F. Marquand, Maurizio Filippone, John Ashburner, Mark Girolami, Janaina Mourao-Miranda, Gareth J. Barker, Steven C. R. Williams, P. Nigel Leigh, and Camilla R. V. Blain ( PLoS ONE 8(7): e69237. doi:10.1371/journal.pone.0069237, XML, HTML, and .pdf format, 10p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069237
A. “Understanding the Relationship between Type 2 Diabetes Mellitus and Falls in Older Adults: A Prospective Cohort Study,” by Tine Roman de Mettelinge, Dirk Cambier, Patrick Calders, Nele Van Den Noortgate, and Kim Delbaere (PLoS ONE 8(6): e67055. doi:10.1371/journal.pone.0067055, XML, HTML, and .pdf format, 5p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0067055
B. “A Functional Magnetic Resonance Imaging Study of Pathophysiological Changes Responsible for Mirror Movements in Parkinson’s Disease,” by Alice Poisson, Benedicte Ballanger, Elise Metereau, Jerome Redoute, Danielle Ibarolla, Jean-Christophe Comte, Helene Gervais Bernard, Marie Vidailhet, Emmanuel Broussolle, and Stephane Thobois (PLoS ONE 8(6): e66910. doi:10.1371/journal.pone.0066910, XML, HTML, and .pdf format, 6p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0066910
C. “Complexity of Motor Sequences and Cortical Reorganization in Parkinson’s Disease: A Functional MRI Study,” by Stefano Caproni, Marco Muti, Massimo Principi, Pierfausto Ottaviano, Domenico Frondizi, Giuseppe Capocchi, Piero Floridi, Aroldo Rossi, Paolo Calabresi, and Nicola Tambasco (PLoS ONE 8(6): e66834. doi:10.1371/journal.pone.0066834, XML, HTML, and .pdf format, 10p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0066834
“Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation,” by Jean-Francois Trempe, Veronique Sauve, Karl Grenier, Marjan Seirafi, Matthew Y. Tang, Marie Menade, Sameer Al-Abdul-Wahid, Jonathan Krett, Kathy Wong, Guennadi Kozlov, Bhushan Nagar, Edward A. Fon, and Kalle Gehring (Vol. 340, No. 6139, June 21, 2013, p. 1451-1455).
A. “Alcohol Consumption, Types of Alcohol, and Parkinson’s Disease,” by Rui Liu, Xuguang Guo, Yikyung Park, Jian Wang, Xuemei Huang, Albert Hollenbeck, Aaron Blair, and Honglei Chen (PLoS ONE 8(6): e66452. doi:10.1371/journal.pone.0066452, HTML, XML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0066452
B. “Longitudinal Assessment of Amyloid Pathology in Transgenic ArcA{beta} Mice Using Multi-Parametric Magnetic Resonance Imaging,” by Jan Klohs, Igna Wojtyna Politano, Andreas Deistung, Joanes Grandjean, Anna Drewek, Marco Dominietto, Ruth Keist, Ferdinand Schweser, Jurgen R. Reichenbach, Roger M. Nitsch, Irene Knuesel, and Markus Rudin (PLoS ONE 8(6): e66097. doi:10.1371/journal.pone.0066097, XML, HTML, and .pdf format, 12p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0066097
C. “Outcomes of a Geriatric Liaison Intervention to Prevent the Development of Postoperative Delirium in Frail Elderly Cancer Patients: Report on a Multicentre, Randomized, Controlled Trial,” by Liesbeth Hempenius, Joris P. J. Slaets, Dieneke van Asselt, Geertruida H. de Bock, Theo Wiggers, and Barbara L. van Leeuwen (PLoS ONE 8(6): e64834. doi:10.1371/journal.pone.0064834, XML, HTML, and .pdf format, 11p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0064834
Educational Gerontology (Vol. 39, No. 8, August 2013).
www.ingentaconnect.com/content/routledg/uedg/2013/00000039/00000008
Journal of Parkinson’s Disease (Vol. 3, No. 2, 2013).
iospress.metapress.com/content/q0202723np5m/
Rotman International Journal of Pension Management (Vol. 6, No. 1, Spring 2013).
A. “Anatomical Correlates of Cognitive Functions in Early Parkinson’s Disease Patients,” by Roberta Biundo, Massimiliano Calabrese, Luca Weis, Silvia Facchini, Gianluigi Ricchieri, Paolo Gallo, and Angelo Antonini (PLoS ONE 8(5): e64222. doi:10.1371/journal.pone.0064222, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0064222
B. “Abnormal Baseline Brain Activity in Non-Depressed Parkinson’s Disease and Depressed Parkinson’s Disease: A Resting-State Functional Magnetic Resonance Imaging Study,” by Xuyun Wen, Xia Wu, Jiangtao Liu, Ke Li, and Li Yao (PLoS ONE 8(5): e63691. doi:10.1371/journal.pone.0063691, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063691
C. “A Longitudinal Study of Cognition, Proton MR Spectroscopy and Synaptic and Neuronal Pathology in Aging Wild-type and A{beta}PPswe-PS1dE9 Mice,” by Diane Jansen, Valerio Zerbi, Carola I. F. Janssen, Pieter J. W. C. Dederen, Martina P. C. Mutsaers, Anne Hafkemeijer, Anna-Lena Janssen, Cindy L. M. Nobelen, Andor Veltien, Jack J. Asten, Arend Heerschap, and Amanda J. Kiliaan (PLoS ONE 8(5): e63643. doi:10.1371/journal.pone.0063643, XML, HTML, and .pdf format, 17p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063643
D. “Association between Dopamine D4 Receptor Polymorphism and Age Related Changes in Brain Glucose Metabolism,” by Nora D. Volkow, Dardo Tomasi, Gene-Jack Wang, Frank Telang, Joanna S. Fowler, Rita Z. Goldstein, Nelly Klein, Christopher Wong, James M. Swanson, and Elena Shumay (PLoS ONE 8(5): e63492. doi:10.1371/journal.pone.0063492, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063492
“Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan,” by Anil Rana, Michael Rera, and David W. Walker (Vol. 110, No. 21, May 21, 2013, p. 8638-8643).
A. “Diagnostic Value of the Impairment of Olfaction in Parkinson’s Disease,” by Swaantje Casjens, Angelika Eckert, Dirk Woitalla, Gisa Ellrichmann, Michael Turewicz, Christian Stephan, Martin Eisenacher, Caroline May, Helmut E. Meyer, Thomas Bruning, and Beate Pesch (PLoS ONE 8(5): e64735. doi:10.1371/journal.pone.0064735, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0064735
B. “Movement Disorders in Elderly Users of Risperidone and First Generation Antipsychotic Agents: A Canadian Population-Based Study,” by Irina Vasilyeva, Robert G. Biscontri, Murray W. Enns, Colleen J. Metge, and Silvia Alessi-Severini (PLoS ONE 8(5): e64217. doi:10.1371/journal.pone.0064217, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0064217
C. “Intravenous Immunglobulin Binds Beta Amyloid and Modifies Its Aggregation, Neurotoxicity and Microglial Phagocytosis In Vitro,” by Susann Cattepoel, Alexander Schaub, Miriam Ender, Annette Gaida, Alain Kropf, Ursula Guggisberg, Marc W. Nolte, Louis Fabri, Paul A. Adlard, David I. Finkelstein, Reinhard Bolli, and Sylvia M. Miescher (PLoS ONE 8(5): e63162. doi:10.1371/journal.pone.0063162, XML, HTML, and .pdf format, 14p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063162
A. “Effect of Hormone Replacement Therapy on Cardiovascular Outcomes: A Meta-Analysis of Randomized Controlled Trials,” by Dicheng Yang, Jing Li, Zhongxiang Yuan, and Xu Liu (PLoS ONE 8(5): e62329. doi:10.1371/journal.pone.0062329, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062329
B. “Colour Constancy Across the Life Span: Evidence for Compensatory Mechanisms,” by Sophie Wuerger (PLoS ONE 8(5): e63921. doi:10.1371/journal.pone.0063921, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063921
C. “Could Sensory Mechanisms Be a Core Factor That Underlies Freezing of Gait in Parkinson’s Disease?” by Kaylena A. Ehgoetz Martens, Frederico Pieruccini-Faria, and Quincy J. Almeida (PLoS ONE 8(5): e62602. doi:10.1371/journal.pone.0062602, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062602
A. “Metabolic States Following Accumulation of Intracellular Aggregates: Implications for Neurodegenerative Diseases,” by Alexei Vazquez (PLoS ONE 8(5): e63822. doi:10.1371/journal.pone.0063822, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063822
B. “The Relationship between P3 Amplitude and Working Memory Performance Differs in Young and Older Adults,” by Emi Saliasi, Linda Geerligs, Monicque M. Lorist, and Natasha M. Maurits (PLoS ONE 8(5): e63701. doi:10.1371/journal.pone.0063701, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063701
C. “Impairment of Mitochondria in Adult Mouse Brain Overexpressing Predominantly Full-Length, N-Terminally Acetylated Human {alpha}-Synuclein,” by Theodore A. Sarafian, Christopher M. Ryan, Puneet Souda, Eliezer Masliah, Upendra K. Kar, Harry V. Vinters, Gary W. Mathern, Kym F. Faull, Julian P. Whitelegge, and Joseph B. Watson (PLoS ONE 8(5): e63557. doi:10.1371/journal.pone.0063557, XML, HTML, and .pdf format, 15p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063557
D. “Cerebrospinal Fluid Melanin-Concentrating Hormone (MCH) and Hypocretin-1 (HCRT-1, Orexin-A) in Alzheimer’s Disease,” by Frank M. Schmidt, Juergen Kratzsch, Hermann-Josef Gertz, Mandy Tittmann, Ina Jahn, Uta-Carolin Pietsch, Udo X. Kaisers, Joachim Thiery, Ulrich Hegerl, and Peter Schonknecht (PLoS ONE 8(5): e63136. doi:10.1371/journal.pone.0063136, XML, HTML, and .pdf format, 6p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063136
E. “Rapamycin Attenuates the Progression of Tau Pathology in P301S Tau Transgenic Mice,” by Sefika Ozcelik, Graham Fraser, Perrine Castets, Veronique Schaeffer, Zhiva Skachokova, Karin Breu, Florence Clavaguera, Michael Sinnreich, Ludwig Kappos, Michel Goedert, Markus Tolnay, and David Theo Winkler (PLoS ONE 8(5): e62459. doi:10.1371/journal.pone.0062459, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062459
A. “FDG PET and MRI in Logopenic Primary Progressive Aphasia versus Dementia of the Alzheimer’s Type,” by Ajay Madhavan, Jennifer L. Whitwell, Stephen D. Weigand, Joseph R. Duffy, Edythe A. Strand, Mary M. Machulda, Nirubol Tosakulwong, Matthew L. Senjem, Jeffrey L. Gunter, Val J. Lowe, Ronald C. Petersen, Clifford R. Jack, and Keith A. Josephs (PLoS ONE 8(4): e62471. doi:10.1371/journal.pone.0062471, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062471
B. “TOM40 Mediates Mitochondrial Dysfunction Induced by {alpha}-Synuclein Accumulation in Parkinson’s Disease,” by Andreas Bender, Paula Desplats, Brian Spencer, Edward Rockenstein, Anthony Adame, Matthias Elstner, Christoph Laub, Sarina Mueller, Andrew O. Koob, Michael Mante, Emily Pham, Thomas Klopstock, and Eliezer Masliah (PLoS ONE 8(4): e62277. doi:10.1371/journal.pone.0062277, XML, HTML, and .pdf format, 11p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062277
C. “Calcitriol Imparts Neuroprotection In Vitro to Midbrain Dopaminergic Neurons by Upregulating GDNF Expression,” by Rowan P. Orme, Manminder S. Bhangal, and Rosemary A. Fricker (PLoS ONE 8(4): e62040. doi:10.1371/journal.pone.0062040, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062040
D. “Population-Based 5-Year Follow-Up Study in Taiwan of Dementia and Risk of Stroke,” by Mu-En Liu, Shih-Jen Tsai, Wei-Chiao Chang, Chun-Hung Hsu, Ti Lu, Kuo-Sheng Hung, Wen-Ta Chiu, and Wei-Pin Chang (PLoS ONE 8(4): e61771. doi:10.1371/journal.pone.0061771, XML, HTML, and .pdf format, 6p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0061771
“Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization,” by Shireen A. Sarraf, Malavika Raman, Virginia Guarani-Pereira, Mathew E. Sowa, Edward L. Huttlin, Steven P. Gygi & J. Wade Harper (Vol. 496, No. 745, April 17, 2013, p. 372-376).
www.nature.com/nature/journal/v496/n7445/abs/nature12043.html
A. “Hunger in the Absence of Caloric Restriction Improves Cognition and Attenuates Alzheimer’s Disease Pathology in a Mouse Model,” by Emily J. Dhurandhar, David B. Allison, Thomas van Groen, and Inga Kadish (PLoS ONE 8(4): e60437. doi:10.1371/journal.pone.0060437, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0060437
B. “SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians,” by Akinori Miyashita, Asako Koike, Gyungah Jun, Li-San Wang, Satoshi Takahashi, Etsuro Matsubara, Takeshi Kawarabayashi, Mikio Shoji, Naoki Tomita, Hiroyuki Arai, Takashi Asada, Yasuo Harigaya, Masaki Ikeda, Masakuni Amari, Haruo Hanyu, Susumu Higuchi, Takeshi Ikeuchi, Masatoyo Nishizawa, Masaichi Suga, Yasuhiro Kawase, Hiroyasu Akatsu, Kenji Kosaka, Takayuki Yamamoto, Masaki Imagawa, Tsuyoshi Hamaguchi, Masahito Yamada, Takashi Moriaha, Masatoshi Takeda, Takeo Takao, Kenji Nakata, Yoshikatsu Fujisawa, Ken Sasaki, Ken Watanabe, Kenji Nakashima, Katsuya Urakami, Terumi Ooya, Mitsuo Takahashi, Takefumi Yuzuriha, Kayoko Serikawa, Seishi Yoshimoto, Ryuji Nakagawa, Jong-Won Kim, Chang-Seok Ki, Hong-Hee Won, Duk L. Na, Sang Won Seo, Inhee Mook-Jung, The Alzheimer Disease Genetics Consortium, Peter St. George-Hyslop, Richard Mayeux, Jonathan L. Haines, Margaret A. Pericak-Vance, Makiko Yoshida, Nao Nishida, Katsushi Tokunaga, Ken Yamamoto, Shoji Tsuji, Ichiro Kanazawa, Yasuo Ihara, Gerard D. Schellenberg, Lindsay A. Farrer, and Ryozo Kuwano (PLoS ONE 8(4): e58618. doi:10.1371/journal.pone.0058618, XML, HTML, and .pdf format, 11p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058618
C. “Age-Dependent Effects of A53T Alpha-Synuclein on Behavior and Dopaminergic Function,” by Adam W. Oaks, Maya Frankfurt, David I. Finkelstein, and Anita Sidhu (PLoS ONE 8(4): e60378. doi:10.1371/journal.pone.0060378, XML, HTML, and .pdf format, 15p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0060378
D. “Neuroinflammation and Neuronal Loss Precede A{beta} Plaque Deposition in the hAPP-J20 Mouse Model of Alzheimer’s Disease,” by Amanda L. Wright, Raphael Zinn, Barbara Hohensinn, Lyndsey M. Konen, Sarah B. Beynon, Richard P. Tan, Ian A. Clark, Andrea Abdipranoto, and Bryce Vissel (PLoS ONE 8(4): e59586. doi:10.1371/journal.pone.0059586, XML, HTML, and .pdf format, 14p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059586
E. “Time’s Up. Descriptive Epidemiology of Multi-Morbidity and Time Spent on Health Related Activity by Older Australians: A Time Use Survey,” by Tanisha Jowsey, Ian S. McRae, Jose M. Valderas, Paul Dugdale, Rebecca Phillips, Robin Bunton, James Gillespie, Michelle Banfield, Lesley Jones, Marjan Kljakovic, and Laurann Yen (PLoS ONE 8(4): e59379. doi:10.1371/journal.pone.0059379, XML, HTML, and .pdf format, 6p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059379
Journal of Parkinson’s Disease (Vol. 3, No. 1, 2013).
iospress.metapress.com/content/x7246m80h058/
Research on Aging (Vol. 35, No. 3, May 2013).
A. “Waist Circumference, Not Body Mass Index, Is Associated with Renal Function Decline in Korean Population: Hallym Aging Study,” by Hyunju Oh, Shan Ai Quan, Jin-Young Jeong, Soong-Nang Jang, Jung Eun Lee, and Dong-Hyun Kim (PLoS ONE 8(3): e59071. doi:10.1371/journal.pone.0059071, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059071
B. “Mortality Risk amongst Nursing Home Residents Evacuated after the Fukushima Nuclear Accident: A Retrospective Cohort Study,” by Shuhei Nomura, Stuart Gilmour, Masaharu Tsubokura, Daisuke Yoneoka, Amina Sugimoto, Tomoyoshi Oikawa, Masahiro Kami, and Kenji Shibuya (PLoS ONE 8(3): e60192. doi:10.1371/journal.pone.0060192, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0060192
C. “Ovariectomy Induces a Shift in Fuel Availability and Metabolism in the Hippocampus of the Female Transgenic Model of Familial Alzheimer’s,” by Fan Ding, Jia Yao, Liqin Zhao, Zisu Mao, Shuhua Chen, and Roberta Diaz Brinton (PLoS ONE 8(3): e59825. doi:10.1371/journal.pone.0059825, XML, HTML, and .pdf format, 11p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059825
D. “Characterization of a Single-Chain Variable Fragment Recognizing a Linear Epitope of A{beta}: A Biotechnical Tool for Studies on Alzheimer’s Disease?” by Silke Dornieden, Andreas Müller-Schiffmann, Heinrich Sticht, Nan Jiang, Yeliz Cinar, Michael Wordehoff, Carsten Korth, Susanne Aileen Funke, and Dieter Willbold (PLoS ONE 8(3): e59820. doi:10.1371/journal.pone.0059820, XML, HTML, and .pdf format, 11p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059820
E. “Enhanced Functional Connectivity between Putamen and Supplementary Motor Area in Parkinson’s Disease Patients,” by Rongjun Yu, Bo Liu, Lingling Wang, Jun Chen, and Xian Liu (PLoS ONE 8(3): e59717. doi:10.1371/journal.pone.0059717, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059717
A. “Interplay of LRRK2 with chaperone-mediated autophagy,” by Samantha J. Orenstein, Sheng-Han Kuo, Inmaculada Tasset, Esperanza Arias, Hiroshi Koga, Irene Fernandez-Carasa, Etty Cortes, Lawrence S Honig, William Dauer, Antonella Consiglio, Angel Raya, David Sulzer and Ana Maria Cuervo (Vol. 16, No. 4, April 2013, p. 394-406).
www.nature.com/neuro/journal/v16/n4/abs/nn.3350.html
B. “Low hippocampal PI(4,5)P2 contributes to reduced cognition in old mice as a result of loss of MARCKS,” by Laura Trovo, Tariq Ahmed, Zsuzsanna Callaerts-Vegh, Andrea Buzzi, Claudia Bagni, Marinee Chuah, Thierry VandenDriessche, Rudi D’Hooge, Detlef Balschun and Carlos G. Dotti (Vol. 16, No. 4, April 2013, p. 449-455).
A. “Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity,” by Neda Jahanshad, Priya Rajagopalan, Xue Hua, Derrek P. Hibar, Talia M. Nir, Arthur W. Toga, Clifford R. Jack, Jr, Andrew J. Saykin, Robert C. Green, Michael W. Weiner, Sarah E. Medland, Grant W. Montgomery, Narelle K. Hansell, Katie L. McMahon, Greig I. de Zubicaray, Nicholas G. Martin, Margaret J. Wright, Paul M. Thompson, and the Alzheimer’s Disease Neuroimaging Initiative (Vol. 110, No. 12, March 19, 2013, .pdf and HTML format, p. 4768-4773). Note: PNAS is providing open access to the full-text of this article.
www.pnas.org/content/110/12/4768.abstract.html?etoc
B. “Exaggerated phase-amplitude coupling in the primary motor cortex in Parkinson disease,” by Coralie de Hemptinne, Elena S. Ryapolova-Webb, Ellen L. Air, Paul A. Garcia, Kai J. Miller, Jeffrey G. Ojemann, Jill L. Ostrem, Nicholas B. Galifianakis, and Philip A. Starr (Vol. 110, No. 12, March 19, 2013, p. 4780-4785).
Note: Lancet requires free registration prior to providing content.
A. “Amyloid {beta} deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer’s disease: a prospective cohort study,” by Victor L. Villemagne, Samantha Burnham, Pierrick Bourgeat, Belinda Brown, Kathryn A. Ellis, Olivier Salvado, Cassandra Szoeke, S. Lance Macaulay, Ralph Martins, Paul Maruff, David Ames, Christopher C. Rowe, and Colin L. Masters, for the Australian Imaging Biomarkers and Lifestyle (AIBL) Research Group (Vol. 12, No. 4, April 4, p. 357-367).
www.thelancet.com/journals/laneur/article/PIIS1474-4422%2813%2970044-9/abstract
B. “Extended-release carbidopa-levodopa (IPX066) compared with immediate-release carbidopa-levodopa in patients with Parkinson’s disease and motor fluctuations: a phase 3 randomised, double-blind trial,” by Robert A. Hauser, Ann Hsu, Sherron Kell, Alberto J. Espay, Kapil Sethi, Mark Stacy, William Ondo, Martin O’Connell, and Suneel Gupta, for the IPX066 ADVANCE-PD investigators (Vol. 12, No. 4, April 4, p. 346-356).
www.thelancet.com/journals/laneur/article/PIIS1474-4422%2813%2970025-5/abstract
A. “Subclinical Thyroid Dysfunction and Cognitive Decline in Old Age,” by Liselotte W. Wijsman, Anton J. M. de Craen, Stella Trompet, Jacobijn Gussekloo, David J. Stott, Nicolas Rodondi, Paul Welsh, J. Wouter Jukema, Rudi G. J. Westendorp, and Simon P. Mooijaart (PLoS ONE 8(3): e59199. doi:10.1371/journal.pone.0059199, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059199
B. “PINCH in the Cellular Stress Response to Tau-Hyperphosphorylation,” by Ahmet Yunus Ozdemir, Inna Rom, Jane Kovalevich, William Yen, Radhika Adiga, Rajnish S. Dave, and Dianne Langford (PLoS ONE 8(3): e58232. doi:10.1371/journal.pone.0058232, XML, HTML, and .pdf format, 11p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058232
C. “Single-Subject Grey Matter Graphs in Alzheimer’s Disease,” by Betty M. Tijms, Christiane Moller, Hugo Vrenken, Alle Meije Wink, Willem de Haan, Wiesje M. van der Flier, Cornelis J. Stam, Philip Scheltens, and Frederik Barkhof (PLoS ONE 8(3): e58921. doi:10.1371/journal.pone.0058921, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058921
D. “United States Acculturation and Cancer Patients’ End-of-Life Care,” by Alexi A. Wright, Heather Stieglitz, Yankel M. Kupersztoch, M. Elizabeth Paulk, Yookyung Kim, Ingrid T. Katz, Francisco Munoz, Rachel B. Jimenez, Jan Mutchler, Lorna Rivera, Anthony L. Back, and Holly G. Prigerson (PLoS ONE 8(3): e58663. doi:10.1371/journal.pone.0058663, XML, HTML, and .pdf format, 10p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058663
E. “Force Control Deficits in Individuals with Parkinson’s Disease, Multiple Systems Atrophy, and Progressive Supranuclear,” by Palsy Kristina A. Neely, Peggy J. Planetta, Janey Prodoehl, Daniel M. Corcos, Cynthia L. Comella, Christopher G. Goetz, Kathleen L. Shannon, and David E. Vaillancourt (PLoS ONE 8(3): e58403. doi:10.1371/journal.pone.0058403, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058403
A. “Promotion of physical activity and fitness in sedentary patients with Parkinson’s disease: randomised controlled trial,” by Marlies van Nimwegen, Arlene D. Speelman, Sebastiaan Overeem, Bart P. van de Warrenburg, Katrijn Smulders, Manon L. Dontje, George F. Borm, Frank J. G. Backx, Bastiaan R. Bloem, and Marten Munneke, on behalf of the ParkFit Study Group (Vol. 346, No. 7898, BMJ 2013;346:f576, .pdf and HTML format).
www.bmj.com/content/346/bmj.f576
B. “Income inequality and 30 day outcomes after acute myocardial infarction, heart failure, and pneumonia: retrospective cohort study,” by Peter K. Lindenauer, Tara Lagu, Michael B. Rothberg, Jill Avrunin, Penelope S. Pekow, Yongfei Wang, and Harlan M. Krumholz (Vol. 346, No. 7898, BMJ 2013;346:f521, .pdf and HTML format).
A. “Organisational Culture in Residential Aged Care Facilities: A Cross-Sectional Observational Study,” by Christopher Etherton-Beer, Lorraine Venturato, and Barbara Horner (PLoS ONE 8(3): e58002. doi:10.1371/journal.pone.0058002, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058002
B. “Site-Specific Perturbations of Alpha-Synuclein Fibril Structure by the Parkinson’s Disease Associated Mutations A53T and E46K,” by Luisel R. Lemkau, Gemma Comellas, Shin W. Lee, Lars K. Rikardsen, Wendy S. Woods, Julia M. George, and Chad M. Rienstra (PLoS ONE 8(3): e49750. doi:10.1371/journal.pone.0049750, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0049750
C. “Ginsenoside Rg1 Decreases A{beta}1-42 Level by Upregulating PPAR? and IDE Expression in the Hippocampus of a Rat Model of Alzheimer’s Disease,” by QianKun Quan, Jue Wang, Xi Li, and Yi Wang (PLoS ONE 8(3): e59155. doi:10.1371/journal.pone.0059155, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059155
D. “Oleuropein Aglycone Protects Transgenic C. elegans Strains Expressing A{beta}42 by Reducing Plaque Load and Motor Deficit,” by Luisa Diomede, Stefania Rigacci, Margherita Romeo, Massimo Stefani, and Mario Salmona (PLoS ONE 8(3): e58893. doi:10.1371/journal.pone.0058893, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058893
E. “The Proton-Pump Inhibitor Lansoprazole Enhances Amyloid Beta Production,” by Nahuai Badiola, Victor Alcalde, Albert Pujol, Lisa-Marie Munter, Gerd Multhaup, Alberto Lleo, Mireia Coma, Montserrat Soler-Lopez, and Patrick Aloy (PLoS ONE 8(3): e58837. doi:10.1371/journal.pone.0058837, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058837
F. “Socio-Economic Position Has No Effect on Improvement in Health-Related Quality of Life and Patient Satisfaction in Total Hip and Knee Replacement: A Cohort Study,” by J. Christiaan Keurentjes, David Blane, Melanie Bartley, Johan J. B. Keurentjes, Marta Fiocco, and Rob G. Nelissen (PLoS ONE 8(3): e56785. doi:10.1371/journal.pone.0056785, XML, HTML, and .pdf format, 11p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0056785
A. “Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-{beta} species,” by Suk-Joon Hyung, Alaina S. DeToma, Jeffrey R. Brender, Sanghyun Lee, Subramanian Vivekanandan, Akiko Kochi, Jung-Suk Choi, Ayyalusamy Ramamoorthy, Brandon T. Ruotolo, and Mi Hee Lim (Vol. 110, No. 10, March 5, 2013, p. 3743-3748).
www.pnas.org/content/110/10/3743.abstract
B. “Metabotropic NMDA receptor function is required for {beta}-amyloid-induced synaptic depression,” by Helmut W. Kessels, Sadegh Nabavi, and Roberto Malinow (Vol. 110, No. 10, March 5, 2013, p. 4033-4038).
www.pnas.org/content/110/10/4033.abstract
C. “Large {alpha}-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking,” by Bong-Kyu Choi, Mal-Gi Choi, Jae-Yeol Kim, Yoosoo Yang, Ying Lai, Dae-Hyuk Kweon, Nam Ki Lee, and Yeon-Kyun Shin (Vol. 110, No. 10, March 5, 2013, p. 4087-4092).
A. “Is R2* a New MRI Biomarker for the Progression of Parkinson’s Disease? A Longitudinal Follow-Up,” by Miguel Ulla, Jean Marie Bonny, Lemlih Ouchchane, Isabelle Rieu, Beatrice Claise, and Franck Durif (PLoS ONE 8(3): e57904. doi:10.1371/journal.pone.0057904, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0057904
B. “The Effects of Housework on the Health of Retired Older Adults: A Preliminary Investigation from the Tongji-Dongfeng Cohort Study,” by China Xiaopiao Wen, Yuan Liang, Jiang Zhu, and Tangchun Wu (PLoS ONE 8(3): e57232. doi:10.1371/journal.pone.0057232, XML, HTML, and .pdf format, 6p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0057232
A. “Research on a Community-based Platform for Promoting Health and Physical Fitness in the Elderly Community,” by Tsai-Hsuan Tsai, Alice May-Kuen Wong, Chien-Lung Hsu, and Kevin C. Tseng (PLoS ONE 8(2): e57452. doi:10.1371/journal.pone.0057452, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0057452
B. “A Proposal for a Comprehensive Grading of Parkinson’s Disease Severity Combining Motor and Non-Motor Assessments: Meeting an Unmet Need,” by Kallol Ray Chaudhuri, Jose Manuel Rojo, Anthony H. V. Schapira, David J. Brooks, Fabrizio Stocchi, Per Odin, Angelo Antonini, Richard J. Brown, and Pablo Martinez-Martin (PLoS ONE 8(2): e57221. doi:10.1371/journal.pone.0057221, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0057221
C. “Detection of Amyloid Plaques Targeted by Bifunctional USPIO in Alzheimer’s Disease Transgenic Mice Using Magnetic Resonance Microimaging,” by Youssef Zaim Wadghiri, Jialin Li, Jinhuan Wang, Dung Minh Hoang, Yanjie Sun, Hong Xu, Wai Tsui, Yongsheng Li, Allal Boutajangout, Andrew Wang, Mony de Leon, and Thomas Wisniewski (PLoS ONE 8(2): e57097. doi:10.1371/journal.pone.0057097, XML, HTML, and .pdf format, 10p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0057097
“Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies,” by S. Pablo Sardi, Jennifer Clarke, Catherine Viel, Monyrath Chan, Thomas J. Tamsett, Christopher M. Treleaven, Jie Bu, Lindsay Sweet, Marco A. Passini, James C. Dodge, W. Haung Yu, Richard L. Sidman, Seng H. Cheng, and Lamya S. Shihabuddin (Vol. 110, No. 9, February 26, 2013, .pdf and HTML format, p. 3537-3542). Note: PNAS is providing open access to the full-text of this article.
“Neurostimulation for Parkinson’s Disease with Early Motor Complication,” by W.M.M. Schuepbach, J. Rau, K. Knudsen, J. Volkmann, P. Krack, L. Timmermann, T.D. Halbig, H. Hesekamp, S.M. Navarro, N. Meier, D. Falk, M. Mehdorn, S. Paschen, M. Maarouf, M.T. Barbe, G.R. Fink, A. Kupsch, D. Gruber, G.-H. Schneider, E. Seigneuret, A. Kistner, P. Chaynes, F. Ory-Magne, C. Brefel Courbon, J. Vesper, A. Schnitzler, L. Wojtecki, J.-L. Houeto, B. Bataille, D. Maltete, P. Damier, S. Raoul, F. Sixel-Doering, D. Hellwig, A. Gharabaghi, R. Krüger, M.O. Pinsker, F. Amtage, J.-M. Regis, T. Witjas, S. Thobois, P. Mertens, M. Kloss, A. Hartmann, W.H. Oertel, B. Post, H. Speelman, Y. Agid, C. Schade-Brittinger, and G. Deuschl for the EARLYSTIM Study Group (Vol. 368, No. 7, February 14, 2013, p. 610-622).
www.nejm.org/doi/full/10.1056/NEJMoa1205158?query=TOC#t=abstract
A. “Plasma Adiponectin Levels Correlate Positively with an Increasing Number of Components of Frailty in Male Elders,” by Jaw-Shiun Tsai, Chih-Hsun Wu, Su-Chiu Chen, Kuo-Chin Huang, Chin-Ying Chen, Ching-I Chang, Lee-Ming Chuang, and Ching-Yu Chen (PLoS ONE 8(2): e56250. doi:10.1371/journal.pone.0056250, XML, HTML, and .pdf format, 8p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0056250
B. “The Effects of Aging on Conflict Detection,” by Giuliana Lucci, Marika Berchicci, Donatella Spinelli, Francesco Taddei, and Francesco Di Russo (PLoS ONE 8(2): e56566. doi:10.1371/journal.pone.0056566, XML, HTML, and .pdf format, 14p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0056566
C. “Motor Matters: Tackling Heterogeneity of Parkinson’s Disease in Functional MRI Studies,” by Stefan Holiga, Karsten Mueller, Harald E. Moller, Tomas Sieger, Matthias L. Schroeter, Josef Vymazal, Evzen Ruzicka, and Robert Jech (PLoS ONE 8(2): e56133. doi:10.1371/journal.pone.0056133, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0056133
D. “Accelerated Cell Aging in Female APOE-{epsilon}4 Carriers: Implications for Hormone Therapy Use,” by Emily G. Jacobs, Candyce Kroenke, Jue Lin, Elissa S. Epel, Heather A. Kenna, Elizabeth H. Blackburn, and Natalie L. Rasgon (PLoS ONE 8(2): e54713. doi:10.1371/journal.pone.0054713, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0054713
E. “Increased Tau Phosphorylation and Tau Truncation, and Decreased Synaptophysin Levels in Mutant BRI2/Tau Transgenic Mice,” by Holly J. Garringer, Jill Murrell, Neeraja Sammeta, Anita Gnezda, Bernardino Ghetti, and Ruben Vidal ( PLoS ONE 8(2): e56426. doi:10.1371/journal.pone.0056426, XML, HTML, and .pdf format, 11p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0056426
A. “Relationship between Plasma Analytes and SPARE-AD Defined Brain Atrophy Patterns in ADNI,” by Jon B. Toledo, Xiao Da, Priyanka Bhatt, David A. Wolk, Steven E. Arnold, Leslie M. Shaw, John Q. Trojanowski, and Christos Davatzikos, Alzheimer’s Disease Neuroimaging Initiative (PLoS ONE 8(2): e55531. doi:10.1371/journal.pone.0055531, XML, HTML, and .pdf format, 10p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0055531
B. “Calorie Restriction Hysteretically Primes Aging Saccharomyces cerevisiae toward More Effective Oxidative Metabolism,” by Erich B. Tahara, Fernanda M. Cunha, Thiago O. Basso, Bianca E. Della Bianca, Andreas K. Gombert, and Alicia J. Kowaltowski (PLoS ONE 8(2): e56388. doi:10.1371/journal.pone.0056388, XML, HTML, and .pdf format, 11p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0056388
C. “The Pathogenic A{beta}43 Is Enriched in Familial and Sporadic Alzheimer Disease,” by Anna Sandebring, Hedvig Welander, Bengt Winblad, Caroline Graff, and Lars O. Tjernberg (PLoS ONE 8(2): e55847. doi:10.1371/journal.pone.0055847, XML, HTML, and .pdf format, 10p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0055847
D. “Differentiating Non-Motor Symptoms in Parkinson’s Disease from Controls and Hemifacial Spasm,” by Ming-Hui Yong, John C. Allen, Kumar M. Prakash, and Eng-King Tan (PLoS ONE 8(2): e49596. doi:10.1371/journal.pone.0049596, XML, HTML, and .pdf format, 7p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0049596
“Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells,” by Emma R. Andersson, Carmen Salto, J. Carlos Villaescusa, Lukas Cajanek, Shanzheng Yang, Lenka Bryjova, Irina I. Nagy, Seppo J. Vainio, Carmen Ramirez, Vitezslav Bryja, and Ernest Arenas (Vol. 110, No. 7, February 12, 2013, .pdf and HTML format, p. E602-E610).
A. “CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging,” by Kuti Baruch, Noga Ron-Harel, Hilah Gal, Aleksandra Deczkowska, Eric Shifrut, Wilfred Ndifon, Nataly Mirlas-Neisberg, Michal Cardon, Ilan Vaknin, Liora Cahalon, Tamara Berkutzki, Mark P. Mattson, Fernando Gomez-Pinilla, Nir Friedman, and Michal Schwartz (Vol. 110, No. 6, February 5, 2013, p. 2264-2269).
www.pnas.org/content/110/6/2264.abstract
B. “Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons,” by Banafsheh Kadkhodaei, Alexandra Alvarsson, Nicoletta Schintu, Daniel Ramskold, Nikolaos Volakakis, Eliza Joodmardi, Takashi Yoshitake, Jan Kehr, Mickael Decressac, Anders Bjorklund, Rickard Sandberg, Per Svenningsson, and Thomas Perlmann (Vol. 110, No. 6, February 5, 2013, p. 2360-2365).
A. “A Reliable Way to Detect Endogenous Murine {beta}-Amyloid,” by Andrew F. Teich, Mitesh Patel, and Ottavio Arancio (PLoS ONE 8(2): e55647. doi:10.1371/journal.pone.0055647, XML, HTML, and .pdf format, 5p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0055647
B. “Striatal Glutamate Release in l-DOPA-Induced Dyskinetic Animals,” by Nina Nevalainen, Martin Lundblad, Greg A. Gerhardt, and Ingrid Stromberg (PLoS ONE 8(2): e55706. doi:10.1371/journal.pone.0055706, XML, HTML, and .pdf format, 9p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0055706
“Obsessive Compulsive Personality Disorder and Parkinson’s Disease,” by Alessandra Nicoletti, Antonina Luca, Loredana Raciti, Donatella Contrafatto, Elisa Bruno, Valeria Dibilio, Giorgia Sciacca, Giovanni Mostile, Antonio Petralia, and Mario Zappia (PLoS ONE 8(1): e54822. doi:10.1371/journal.pone.0054822, XML, HTML, and .pdf format, 5p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0054822
A. “Hypoxia Promotes Dopaminergic Differentiation of Mesenchymal Stem Cells and Shows Benefits for Transplantation in a Rat Model of Parkinson’s Disease,” by Yue Wang, Jian Yang, Haisheng Li, Xuan Wang, Lingling Zhu, Ming Fan, and Xiaomin Wang (PLoS ONE 8(1): e54296. doi:10.1371/journal.pone.0054296, XML, HTML, and .pdf format, 12p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0054296
B. “High Glucose Induced Alteration of SIRTs in Endothelial Cells Causes Rapid Aging in a p300 and FOXO Regulated Pathway,” by Rokhsana Mortuza, Shali Chen, Biao Feng, Subhrojit Sen, and Subrata Chakrabarti ( PLoS ONE 8(1): e54514. doi:10.1371/journal.pone.0054514, XML, HTML, and .pdf format, 13p.).
www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0054514
“NIH launches collaborative effort to find biomarkers for Parkinson’s,” (January 15, 2013).
“Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease,” by Arthur G. Fitzmaurice, Shannon L. Rhodes, Aaron Lulla, Niall P. Murphy, Hoa A. Lam, Kelley C. O’Donnell, Lisa Barnhill, John E. Casida, Myles Cockburn, Alvaro Sagasti, Mark C. Stahl, Nigel T. Maidment, Beate Ritz, and Jeff M. Bronstein (Vol. 110, No. 2, January 9, 2013, p. 636-641).
A. “Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila,” by Michael Reraa, Rebecca I. Clark, and David W. Walker (Vol. 109, No. 52, December 26, 2012, p. 21528-21533).
www.pnas.org/content/109/52/21528.abstract.html?etoc
B. “Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration,” by Xiqun Chen, Thomas C. Burdett, Cody A. Desjardins, Robert Logan, Sara Cipriani, Yuehang Xu, and Michael A. Schwarzschild (Vol. 110, No. 1, January 2, 2013, p. 300-305).
Note: Lancet requires free registration prior to providing access. “Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson’s disease (NSTAPS study): a randomised controlled trial,” by Vincent J.J. Odekerken, Teus van Laar, Michiel J. Staal, Arne Mosch, Carel F.E. Hoffmann, Peter C.G. Nijssen, Guus N. Beute, Jeroen P.P. van Vugt, Mathieu W.P.M. Lenders, M. Fiorella Contarino, Marieke S.J. Mink, Lo J. Bour, Pepijn van den Munckhof, Ben A. Schmand, Rob J. de Haan, P. Richard Schuurman, and Rob M.A. de Bie (Vol. 12, No. 1, January 2013, p. 37-44).
www.thelancet.com/journals/laneur/article/PIIS1474-4422%2812%2970264-8/abstract
A. “Direct three-dimensional visualization of membrane disruption by amyloid fibrils,” by Lilia Milanesi, Tania Sheynis, Wei-Feng Xue, Elena V. Orlova, Andrew L. Hellewell, Raz Jelinek, Eric W. Hewitt, Sheena E. Radford, and Helen R. Saibil (Vol. 109, No. 50, December 11, 2012, p. 20455-20460).
www.pnas.org/content/109/50/20455.abstract
B. “CCR2 chemokine receptor signaling mediates pain in experimental osteoarthritis,” by Rachel E. Miller, Phuong B. Tran, Rosalina Das, Nayereh Ghoreishi-Haack, Dongjun Ren, Richard J. Miller, and Anne-Marie Malfait (Vol. 109, No. 50, December 11, 2012, p. 20602-20607).
www.pnas.org/content/109/50/20602.abstract
C. “Prefrontal D1 dopamine signaling is required for temporal control,” by Nandakumar S. Narayanan, Benjamin B. Land, John E. Solder, Karl Deisseroth, and Ralph J. DiLeone (Vol. 109, No. 50, December 11, 2012, p. 20726-20731).
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