CDHA CAAR

April 10, 2014

CAAR – US National Institutes of Health Press Release – April 10, 2014

Filed under: Reports and Articles — Tags: — admin @ 4:41 pm

Too much protein may kill brain cells as Parkinson’s progresses,” (April 10, 2014).

www.nih.gov/news/health/apr2014/ninds-10.htm

March 31, 2014

CAAR – Lancet Article Abstract – March 31, 2014

Filed under: Reports and Articles — Tags: — admin @ 4:40 pm

Note: Lancet requires free registration prior to providing content: “Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson’s disease: a dose escalation, open-label, phase 1/2 trial,” by Stephane Palfi, Jean Marc Gurruchaga, G Scott Ralph, Helene Lepetit, Sonia Lavisse, Philip C. Buttery, Colin Watts, James Miskin, Michelle Kelleher, Sarah Deeley, Hirokazu Iwamuro, Jean Pascal Lefaucheur, Claire Thiriez, Gilles Fenelon, Cherry Lucas, Pierre Brugieres, Inanna Gabriel, Kou Abhay, Xavier Drouot, Naoki Tani, Aurelie Kas, Bijan Ghaleh, Philippe Le Corvoisier, Patrice Dolphin, David P Breen, Sarah Mason, Natalie Valle Guzman, Nicholas D. Mazarakis, Pippa A. Radcliffe, Richard Harrop, Susan M. Kingsman, Olivier Rascol, Stuart Naylor, Roger A. Barker, Philippe Hantraye, Philippe Remy, Pierre Cesaro, and Kyriacos A. Mitrophanous (Vol. 383, No. 9923, March 29, 2014, p. 1138-1147).

www.thelancet.com/journals/lancet/article/PIIS0140-6736%2813%2961939-X/abstract

March 18, 2014

CAAR – Proceedings of the National Academy of Sciences Article Abstracts – March 18, 2014

Filed under: Reports and Articles — Tags: , — admin @ 4:40 pm

A. “Clioquinol promotes the degradation of metal-dependent amyloid-{beta} (A{beta}) oligomers to restore endocytosis and ameliorate A{beta} toxicity,” by Kent E. S. Matlack, Daniel F. Tardiff, Priyanka Narayan, Shusei Hamamichi, Kim A. Caldwell, Guy A. Caldwell, and Susan Lindquist (Vol. 111, No. 11, March 18, 2014, p. 4013-4018).

www.pnas.org/content/111/11/4013.abstract

B. “Parkinson disease-associated mutation R1441H in LRRK2 prolongs the ‘active state’ of its GTPase domain,” by Jingling Liao, Chun-Xiang Wu, Christopher Burlak, Sheng Zhang, Heather Sahm, Mu Wang, Zhong-Yin Zhang, Kurt W. Vogel, Mark Federici, Steve M. Riddle, R. Jeremy Nichols, Dali Liu, Mark R. Cookson, Todd A. Stone, and Quyen Q. Hoang (Vol. 111, No. 11, March 18, 2014, p. 4055-4060).

www.pnas.org/content/111/11/4055.abstract

February 27, 2014

CAAR – Public Library of Science (PLoS) Articles – February 27, 2014

Filed under: Reports and Articles — Tags: , , — admin @ 4:06 pm

A. “Sleep-Wake Cycle in Young and Older Persons with a Lifetime History of Mood Disorders,” by Rebecca Robillard, Sharon L. Naismith, Kristie Leigh Smith, Naomi L. Rogers, Django White, Zoe Terpening, Tony K. C. Ip, Daniel F. Hermens, Bradley Whitwell, Elizabeth M. Scott, and Ian B. Hickie (PLoS ONE 9(2): e87763. doi:10.1371/journal.pone.0087763, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0087763

B. “Differential Expression of Alpha-Synuclein in Hippocampal Neurons,” by Katsutoshi Taguchi, Yoshihisa Watanabe, Atsushi Tsujimura, Harutsugu Tatebe, Seiji Miyata, Takahiko Tokuda, Toshiki Mizuno, and Masaki Tanaka (PLoS ONE 9(2): e89327. doi:10.1371/journal.pone.0089327, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0089327

February 25, 2014

CAAR – Nature Neuroscience Article Abstracts – February 25, 2014

Filed under: Reports and Articles — Tags: , — admin @ 4:51 pm

A. “Tau promotes neurodegeneration through global chromatin relaxation,” by Bess Frost, Martin Hemberg, Jada Lewis and Mel B. Feany (Vol. 17, No. 3, March 2014, p. 357-366).

www.nature.com/neuro/journal/v17/n3/abs/nn.3639.html

B. “LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity,” by Loukia Parisiadou, Jia Yu, Carmelo Sgobio, Chengsong Xie, Guoxiang Liu, Lixin Sun, Xing-Long Gu, Xian Lin, Nicole A Crowley, David M Lovinger & Huaibin Cai (Vol. 17, No. 3, March 2014, p. 367-376).

www.nature.com/neuro/journal/v17/n3/abs/nn.3636.html

February 18, 2014

CAAR – Proceedings of the National Academy of Sciences Article Abstracts – February 18, 2014

Filed under: Reports and Articles — Tags: , — admin @ 4:29 pm

A. “Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease,” by Alexandria Beilina, Iakov N. Rudenko, Alice Kaganovich, Laura Civiero, Hien Chau, Suneil K. Kalia, Lorraine V. Kalia, Evy Lobbestael, Ruth Chia, Kelechi Ndukwe, Jinhui Ding, Mike A. Nalls, International Parkinson’s Disease Genomics Consortium, North American Brain Expression Consortium, Maciej Olszewski, David N. Hauser, Ravindran Kumaran, Andres M. Lozano, Veerle Baekelandt, Lois E. Greene, Jean-Marc Taymans, Elisa Greggio, and Mark R. Cookson (Vol. 111, No. 7, February 18, 2014, p. 2626-2631).

www.pnas.org/content/111/7/2626.abstract

B. “Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid-{beta} accumulation modifier,” by Takashi Morihara, Noriyuki Hayashi, Mikiko Yokokoji, Hiroyasu Akatsu, Michael A. Silverman, Nobuyuki Kimura, Masahiro Sato, Yuhki Saito, Toshiharu Suzuki, Kanta Yanagida, Takashi S. Kodama, Toshihisa Tanaka, Masayasu Okochi, Shinji Tagami, Hiroaki Kazui, Takashi Kudo, Ryota Hashimoto, Naohiro Itoh, Kouhei Nishitomi, Yumi Yamaguchi-Kabata, Tatsuhiko Tsunoda, Hironori Takamura, Taiichi Katayama, Ryo Kimura, Kouzin Kamino, Yoshio Hashizume, and Masatoshi Takeda (Vol. 111, No. 7, February 18, 2014, .pdf and HTML format, p. 2638-2643). Note: PNAS is providing open access to the full-text of this article.

www.pnas.org/content/111/7/2638.abstract

February 17, 2014

CAAR – Tables of Contents – February 17, 2014

Filed under: Journal Table of Contents — Tags: , — admin @ 3:00 pm

Journals of Gerontology (B): Psychological Sciences (Vol. 69B, No. 2, March 2014).

psychsocgerontology.oxfordjournals.org/content/69/2.toc

Journal of Parkinson’s Disease (Vol. 4, No. 1, 2014).

iospress.metapress.com/content/l17051u273h7

February 7, 2014

CAAR – Lancet Article Abstract – February 7, 2014

Filed under: Reports and Articles — Tags: — admin @ 4:30 pm

Note: Lancet requires free registration prior to providing access. “Pimavanserin for patients with Parkinson’s disease psychosis: a randomised, placebo-controlled phase 3 trial,” by Jeffrey Cummings, Stuart Isaacson, Roger Mills, Hilde Williams, Kathy Chi-Burris, Anne Corbett, Rohit Dhall, and Prof. Clive Ballard (Vol. 383, No. 9916, February 8, 2014, p. 533-540).

www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)62106-6/abstract

January 31, 2014

CAAR – Nature Cell Biology Article Abstract – January 31, 2014

Filed under: Reports and Articles — Tags: — admin @ 4:29 pm

Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease,” by Roberta Tufi, Sonia Gandhi, Ines P. de Castro, Susann Lehmann, Plamena R. Angelova, David Dinsdale, Emma Deas, Helene Plun-Favreau, Pierluigi Nicotera, Andrey Y. Abramov, Anne E. Willis, Giovanna R. Mallucci, Samantha H. Y. Loh & L. Miguel Martins (Vol. 16, No. 1, January 2014, p. 157-166).

www.nature.com/ncb/journal/v16/n2/abs/ncb2901.html

January 23, 2014

CAAR – Proceedings of the National Academy of Sciences Article – January 23, 2014

Filed under: Reports and Articles — Tags: — admin @ 3:19 pm

“Tau pathology involves protein phosphatase 2A in Parkinsonism-dementia of Guam,” by Mohammad Arif, Syed Faraz Kazim, Inge Grundke-Iqbal, Ralph M. Garrutoc, and Khalid Iqbal (Vol. 111, No. 3, Jan. 21, 2014, HTML and .pdf format,  p. 1144-1149). This article is available free of charge.

www.pnas.org/content/111/3/1144.full

January 22, 2014

CAAR – Lancet Neurology Article Abstract – January 22, 2014

Filed under: Reports and Articles — Tags: — admin @ 4:42 pm

Note: Lancet requires free registration prior to providing access. “Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson’s disease: a randomised, controlled, double-blind, double-dummy study,” by Prof. C. Warren Olanow, Karl Kieburtz, Per Odin, Alberto J. Espay, David G. Standaert, Hubert H. Fernandez, Arvydas Vanagunas, Ahmed A. Othman, Katherine L. Widnell, Weining Z. Robieson, Yili Pritchett, Krai Chatamra, Janet Benesh, Robert A. Lenz, and Angelo Antonini (Vol. 13, No. 2, February 2014, p. 141-149).

www.thelancet.com/journals/laneur/article/PIIS1474-4422(13)70293-X/abstract

January 9, 2014

CAAR – Public Library of Science (PLoS) Article – January 9, 2014

Filed under: Reports and Articles — Tags: — admin @ 4:12 pm

Dopamine Reduction in the Substantia Nigra of Parkinson’s Disease Patients Confirmed by In Vivo Magnetic Resonance Spectroscopic Imaging,” by Adriane Groger, Rupert Kolb, Rita Schafer, and Uwe Klose (PLoS ONE 9(1): e84081. doi:10.1371/journal.pone.0084081, XML, HTML, and .pdf format, p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0084081

December 16, 2013

CAAR – Tables of Contents – December 16, 2013

Filed under: Journal Table of Contents — Tags: , , , , — admin @ 4:21 pm

Ageing and Mental Health (Vol. 18, No. 1, 2014).

www.tandfonline.com/toc/camh20/18/1

Educational Gerontology (Vol. 40, No. 4, April 2013).

www.ingentaconnect.com/content/routledg/uedg/2014/00000040/00000004

Health Economics, Policy and Law (Vol. 9, No. 1, January 2014).

journals.cambridge.org/action/displayIssue?decade=2010&jid=HEP&volumeId=9&issueId=01&iid=9123698

Journal of Parkinson’s Disease (Vol. 3, No. 4, 2013).

iospress.metapress.com/content/m15676085n34/

Journal of Pension Economics and Finance (Vol. 13, No. 1, January 2014).

journals.cambridge.org/action/displayIssue?decade=2010&jid=PEF&volumeId=13&issueId=01&iid=9118408

November 26, 2013

CAAR – Proceedings of the National Academy of Sciences Article Abstracts – November 26, 2013

Filed under: Reports and Articles — Tags: , — admin @ 4:22 pm

A. “BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer’s disease,” by Rebecca M. Burke, Timothy A. Norman, Tarik F. Haydar, Barbara E. Slack, Susan E. Leeman, Jan Krzysztof Blusztajn, and Tiffany J. Mellott (Vol. 110, No. 48, November 26, 2013, p. 19567-19572).

www.pnas.org/content/110/48/19567.abstract

B. “Fungal-derived semiochemical 1-octen-3-ol disrupts dopamine packaging and causes neurodegeneration,” by Arati A. Inamdar, Muhammad M. Hossain, Alison I. Bernstein, Gary W. Miller, Jason R. Richardson, and Joan Wennstrom Bennett (Vol. 110, No. 48, November 26, 2013, p. 19561-19566).

www.pnas.org/content/110/48/19561.abstract

November 22, 2013

CAAR – Science Report Abstract – November 22, 2013

Filed under: Reports and Articles — Tags: — admin @ 5:09 pm

“Identification and Rescue of alpha-Synuclein Toxicity in Parkinson Patient-Derived Neurons,” by Chee Yeun Chung, Vikram Khurana, Pavan K. Auluck, Daniel F. Tardiff, Joseph R. Mazzulli, Frank Soldner, Valeriya Baru, Yali Lou, Yelena Freyzon, Sukhee Cho, Alison E. Mungenast, Julien Muffat, Maisam Mitalipova, Michael D. Pluth, Nathan T. Jui, Birgitt Schule, Stephen J. Lippard, Li-Huei Tsai, Dimitri Krainc, Stephen L. Buchwald, Rudolf Jaenisch, and Susan Lindquist (Vol. 342, No. 6161, November 22, 2013, p. 983-987).

www.sciencemag.org/content/342/6161/983.abstract

November 12, 2013

CAAR – Proceedings of the National Academy of Sciences Article Abstract – November 12, 2013

Filed under: Reports and Articles — Tags: — admin @ 4:43 pm

Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism,” by Daniella Rylander, Vincenza Bagetta, Valentina Pendolino, Elisa Zianni, Shane Grealish, Fabrizio Gardoni, Monica Di Luca, Paolo Calabresi, M. Angela Cenci, and Barbara Picconi (Vol. 110, No. 46, November 12, 2013, p. E4375-E4384).

www.pnas.org/content/110/46/E4375.abstract

October 30, 2013

CAAR – Public Library of Science (PLoS) Articles – October 30, 2013

Filed under: Reports and Articles — Tags: , — admin @ 4:42 pm

A. “Patterns of Frailty in Older Adults: Comparing Results from Higher and Lower Income Countries Using the Survey of Health, Ageing and Retirement in Europe (SHARE) and the Study on Global AGEing and Adult Health (SAGE),” by Kenneth Harttgen, Paul Kowal, Holger Strulik, Somnath Chatterji, and Sebastian Vollmer (PLoS ONE 8(10): e75847. doi:10.1371/journal.pone.0075847, XML, HTML, and .pdf format, 11p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0075847

B. “Altered Resting State Brain Networks in Parkinson’s Disease,” by Martin Gottlich, Thomas F. Munte, Marcus Heldmann, Meike Kasten, Johann Hagenah, and Ulrike M. Kramer (PLoS ONE 8(10): e77336. doi:10.1371/journal.pone.0077336, XML, HTML and .pdf format, 13p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0077336

October 29, 2013

CAAR – Proceedings of the National Academy of Sciences Article Abstracts – October 29, 2013

Filed under: Reports and Articles — Tags: , , — admin @ 4:21 pm

A. “Synthetic polyubiquitinated alpha-Synuclein reveals important insights into the roles of the ubiquitin chain in regulating its pathophysiology,” by Mahmood Haj-Yahya, Bruno Fauvet, Yifat Herman-Bachinsky, Mirva Hejjaoui, Sudhir N. Bavikar, Subramanian Vedhanarayanan Karthikeyan, Aaron Ciechanover, Hilal A. Lashuel, and Ashraf Brik (Vol. 110, No. 44, October 29, 2013, p. 17726-17731).

www.pnas.org/content/110/44/17726.abstract.html?etoc

B. “Depressed pacemaker activity of sinoatrial node myocytes contributes to the age-dependent decline in maximum heart rate,” by Eric D. Larson, Joshua R. St. Clair, Whitney A. Sumner, Roger A. Bannister, and Cathy Proenza (Vol. 110, No. 44, October 29, 2013, p. 18011-18016).

www.pnas.org/content/110/44/18011.abstract

October 1, 2013

CAAR – Public Library of Science (PLoS) Article – October 1, 2013

Filed under: Reports and Articles — Tags: , — admin @ 4:16 pm

Brain Imaging of Vesicular Monoamine Transporter Type 2 in Healthy Aging Subjects by 18F-FP-(+)-DTBZ PET,” by Kun-Ju Lin, Yi-Hsin Weng, Chia-Ju Hsieh, Wey-Yil Lin, Shiaw-Pyng Wey, Mei-Ping Kung, Tzu-Chen Yen, Chin-Song Lu, and Ing-Tsung Hsiao (PLoS ONE 8(9): e75952. doi:10.1371/journal.pone.0075952, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0075952

September 25, 2013

CAAR – Nature Article Abstract – September 25, 2013

Filed under: Reports and Articles — Tags: , — admin @ 5:06 pm

The ubiquitin ligase parkin mediates resistance to intracellular pathogens,” by Paolo S. Manzanillo, Janelle S. Ayres, Robert O. Watson, Angela C. Collins, Gianne Souza, Chris S. Rae, David S. Schneider, Ken Nakamura, Michael U. Shiloh & Jeffery S. Cox (Vol. 501, No. 7468, September 25, 2013, p. 512-516).

www.nature.com/nature/journal/v501/n7468/abs/nature12566.html

CAAR – Tables of Contents – September 25, 2013

Filed under: Journal Table of Contents — Tags: , — admin @ 5:00 pm

Journal of Aging & Social Policy (Vol. 25, No. 4, 2013).

www.tandfonline.com/toc/wasp20/current

Journal of Parkinson’s Disease (Vol. 3, No. 3, 2013).

www.journalofparkinsonsdisease.com/JPD/Current_Issue.html

September 24, 2013

CAAR – Public Library of Science (PLoS) Articles – September 24, 2013

A. “Motor Timing Deficits in Sequential Movements in Parkinson Disease Are Related to Action Planning: A Motor Imagery Study,” by Laura Avanzino, Elisa Pelosin, Davide Martino, and Giovanni Abbruzzese (PLoS ONE 8(9): e75454. doi:10.1371/journal.pone.0075454, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0075454

B. “Huperzine A for Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Randomized Clinical Trials,” by Guoyan Yang, Yuyi Wang, Jinzhou Tian, and Jian-Ping Liu (PLoS ONE 8(9): e74916. doi:10.1371/journal.pone.0074916, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0074916

C. “Age-Related Hearing Loss and the Factors Determining Continued Usage of Hearing Aids among Elderly Community-Dwelling Residents,” by Kunio Mizutari, Takehiro Michikawa, Hideyuki Saito, Yasuhide Okamoto, Chieko Enomoto, Toru Takebayashi, Kaoru Ogawa, and Yuji Nishiwaki (PLoS ONE 8(9): e73622. doi:10.1371/journal.pone.0073622, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0073756

September 18, 2013

CAAR – Lancet Neurology Article Abstracts – September 18, 2013

Filed under: Reports and Articles — Tags: , — admin @ 4:32 pm

A. “Integrated multidisciplinary care in Parkinson’s disease: a non-randomised, controlled trial (IMPACT),” by Marjolein A. van der Marck, Marten Munneke, Wim Mulleners, Edo M. Hoogerwaard, George F. Borm, Sebastiaan Overeem, Bastiaan R. Bloem, for the IMPACT study group (Vol 12, No. 10, October 2013, p. 947-956).

www.thelancet.com/journals/laneur/article/PIIS1474-4422(13)70196-0/abstract

B. “Preclinical Alzheimer’s disease and its outcome: a longitudinal cohort study,” by Stephanie J.B. Vos, Chengjie Xiong, Pieter Jelle Visser, Mateusz S. Jasielec, Jason Hassenstab, Elizabeth A. Grant, Nigel J. Cairns, John C. Morris, David M. Holtzman, and Anne M. Fagan(Vol 12, No. 10, October 2013, p. 957-965).

www.thelancet.com/journals/laneur/article/PIIS1474-4422(13)70194-7/abstract

September 3, 2013

CAAR – Public Library of Science (PLoS) Articles – September 3, 2013

A. “Cognitive Declines Precede and Predict Functional Declines in Aging and Alzheimer’s Disease,” by Laura B. Zahodne, Jennifer J. Manly, Anna MacKay-Brandt, and Yaakov Stern (PLoS ONE 8(9): e73645. doi:10.1371/journal.pone.0073645, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0073645

B. “Long-Term Effects of Statin Treatment in Elderly People: Extended Follow-Up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER),” by Suzanne M. Lloyd, David J. Stott, Anton J. M. de Craen, Patricia M. Kearney, Naveed Sattar, Ivan Perry, Christopher J. Packard, Andrew Briggs, Laura Marchbank, Harry Comber, J. Wouter Jukema, Rudi G. J. Westendorp, Stella Trompet, Brendan M. Buckley, and Ian Ford (PLoS ONE 8(9): e72642. doi:10.1371/journal.pone.0072642, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0072642

C. “Parkinson’s Disease Is Related to an Increased Risk of Ischemic Stroke-A Population-Based Propensity Score-Matched Follow-Up Study,” by Ya-Ping Huang, Li-Sheng Chen, Ming-Fang Yen, Ching-Yuan Fann, Yueh-Hsia Chiu, Hsiu-Hsi Chen, and Shin-Liang Pan (PLoS ONE 8(9): e68314. doi:10.1371/journal.pone.0068314, XML, HTML, and .pdf format, 6p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068314

D. “The Dopamine D3 Receptor Knockout Mouse Mimics Aging-Related Changes in Autonomic Function and Cardiac Fibrosis,” by Tracy L. Johnson, David A. Tulis, Benjamin E. Keeler, Jitka A. Virag, Robert M. Lust, and Stefan Clemens (PLoS ONE 8(8): e74116. doi:10.1371/journal.pone.0074116, XML, HTML, and .pdf format, 12p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0074116

August 28, 2013

CAAR – Nature Neuroscience Article Abstract – August 28, 2013

Filed under: Reports and Articles — Tags: — admin @ 4:58 pm

The Parkinson’s disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy,” by Victoria S. Burchell, David E. Nelson, Alvaro Sanchez-Martinez, Marta Delgado-Camprubi, Rachael M. Ivatt, Joe H. Pogson, Suzanne J. Randle, Selina Wray, Patrick A. Lewis, Henry Houlden, Andrey Y. Abramov, John Hardy, Nicholas W. Wood, Alexander J. Whitworth, Heike Laman & Helene Plun-Favreau (Vol. 16, No. 9, September 2013, p. 1257-1265).

www.nature.com/neuro/journal/v16/n9/abs/nn.3489.html

August 26, 2013

CAAR – Public Library of Science (PLoS) Articles – August 26, 2013

Filed under: Reports and Articles — Tags: , — admin @ 4:21 pm

A. “Elevated Alpha-Synuclein Impairs Innate Immune Cell Function and Provides a Potential Peripheral Biomarker for Parkinson’s Disease,” by Shyra J. Gardai, Wenxian Mao, Birgitt Schüle, Michael Babcock, Sue Schoebel, Carlos Lorenzana, Jeff Alexander, Sam Kim, Heather Glick, Kathryn Hilton, J. Kent Fitzgerald, Manuel Buttini, San-San Chiou, Lisa McConlogue, John P. Anderson, Dale B. Schenk, Frederique Bard, J. William Langston, Ted Yednock, and Jennifer A. Johnston (PLoS ONE 8(8): e71634. doi:10.1371/journal.pone.0071634, XML, HTML, and .pdf format, 21p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0071634

B. “Phototoxic Action Spectrum on a Retinal Pigment Epithelium Model of Age-Related Macular Degeneration Exposed to Sunlight Normalized Conditions,” by Emilie Arnault, Coralie Barrau, Celine Nanteau, Pauline Gondouin, Karine Bigot, Francoise Vienot, Emmanuel Gutman, Valerie Fontaine, Thierry Villette, Denis Cohen-Tannoudji, Jose-Alain Sahel, and Serge Picaud (PLoS ONE 8(8): e71398. doi:10.1371/journal.pone.0071398, XML, HTML, and .pdf format, 12p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0071398

August 2, 2013

CAAR – Public Library of Science (PLoS) Articles – August 2, 2013

Filed under: Reports and Articles — Tags: , , — admin @ 4:12 pm

A. “The Heterogeneity of Early Parkinson’s Disease: A Cluster Analysis on Newly Diagnosed Untreated Patients,” by Roberto Erro, Carmine Vitale, Marianna Amboni, Marina Picillo, Marcello Moccia, Katia Longo, Gabriella Santangelo, Anna De Rosa, Roberto Allocca, Flavio Giordano, Giuseppe Orefice, Giuseppe De Michele, Lucio Santoro, Maria Teresa Pellecchia, and Paolo Barone (PLoS ONE 8(8): e70244. doi:10.1371/journal.pone.0070244, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0070244

B. “Conformational Stability of Fibrillar Amyloid-Beta Oligomers via Protofilament Pair Formation – A Systematic Computational Study,” by Anna Kahler, Heinrich Sticht, Anselm H. C. Horn (PLoS ONE 8(7): e70521. doi:10.1371/journal.pone.0070521, XML, HTML, and .pdf format, 12p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0070521

C. “Defensive Effect of Lansoprazole in Dementia of AD Type in Mice Exposed to Streptozotocin and Cholesterol Enriched Diet,” by Rupinder K. Sodhi and Nirmal Singh (PLoS ONE 8(7): e70487. doi:10.1371/journal.pone.0070487, XML, HTML, and .pdf format, 10p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0070487

D. “Grasping the Changes Seen in Older Adults When Reaching for Objects of Varied Texture,” by Raymond J. Holt, Alexis S. Lefevre, Ian J. Flatters, Pete Culmer, Richard M. Wilkie, Brian W. Henson, Geoff P. Bingham, and Mark Mon-Williams (PLoS ONE 8(7): e69040. doi:10.1371/journal.pone.0069040, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069040

July 25, 2013

CAAR – Public Library of Science (PLoS) Articles – July 25, 2013

Filed under: Reports and Articles — Tags: , , , — admin @ 3:58 pm

A. “Prevalence and Burden of Gait Disorders in Elderly Men and Women Aged 60-97 Years: A Population-Based Study,” by Philipp Mahlknecht, Stefan Kiechl, Bastiaan R. Bloem, Johann Willeit, Christoph Scherfler, Arno Gasperi, Gregorio Rungger, Werner Poewe, and Klaus Seppi (PLoS ONE 8(7): e69627. doi:10.1371/journal.pone.0069627, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069627

B. “Early Enriched Environment Exposure Protects Spatial Memory and Accelerates Amyloid Plaque Formation in APPSwe/PS1L166P Mice,” by Francesca Montarolo, Roberta Parolisi, Eriola Hoxha, Enrica Boda, and Filippo Tempia (PLoS ONE 8(7): e69381. doi:10.1371/journal.pone.0069381, XML, HTML, and .pdf format, 14p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069381

C. “High Glucose Promotes A{beta} Production by Inhibiting APP Degradation,” by Yi Yang, Yili Wu, Shuting Zhang, and Weihong Song (PLoS ONE 8(7): e69824. doi:10.1371/journal.pone.0069824, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069824

D. “Rotigotine Transdermal Patch in Parkinson’s Disease: A Systematic Review and Meta-Analysis,” by Chang-Qing Zhou, Shan-Shan Li, Zhong-Mei Chen, Feng-Qun Li, Peng Lei, and Guo-Guang Peng (PLoS ONE 8(7): e69738. doi:10.1371/journal.pone.0069738, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069738

E. “Dopaminergic Neuronal Imaging in Genetic Parkinson’s Disease: Insights into Pathogenesis,” by Alisdair McNeill, Ruey-Meei Wu, Kai-Yuan Tzen, Patricia C. Aguiar, Jose M. Arbelo, Paolo Barone, Kailash Bhatia, Orlando Barsottini, Vincenzo Bonifati, Sevasti Bostantjopoulou, Rodrigo Bressan, Giovanni Cossu, Pietro Cortelli, Andre Felicio, Henrique B. Ferraz, Joanna Herrera, Henry Houlden, Marcelo Hoexter, Concepcion Isla, Andrew Lees, Oswaldo Lorenzo-Betancor, Niccolo E. Mencacci, Pau Pastor, Sabina Pappata, Maria Teresa Pellecchia, Laura Silveria-Moriyama, Andrea Varrone, Tom Foltynie, and Anthony H. V. Schapira (PLoS ONE 8(7): e69190. doi:10.1371/journal.pone.0069190, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069190

F. “Glucose Metabolism during Resting State Reveals Abnormal Brain Networks Organization in the Alzheimer’s Disease and Mild Cognitive Impairment,” by Gretel Sanabria-Diaz, Eduardo Martínez-Montes, and Lester Melie-Garcia, the Alzheimer’s Disease Neuroimaging Initiative (PLoS ONE 8(7): e68860. doi:10.1371/journal.pone.0068860, XML, HTML, and .pdf format, 25p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0068860

July 19, 2013

CAAR – Lancet Neurology Article Abstract – July 19, 2013

Filed under: Reports and Articles — Tags: — admin @ 3:42 pm

Pramipexole in patients with early Parkinson’s disease (PROUD): a randomised delayed-start trial,” by Prof. Anthony H.V. Schapira, Prof. Michael P. McDermott, Prof. Paolo Barone, Prof Cynthia L. Comella, Stefan Albrecht, Helen H. Hsu, Daniel H. Massey, Prof. Yoshikuni Mizuno, Prof. Werner Poewe, Prof. Olivier Rascol, and Kenneth Marek (Vol. 12, No. 8, August 2013, p. 747-755).

www.thelancet.com/journals/laneur/article/PIIS1474-4422(13)70117-0/abstract

July 16, 2013

CAAR – Public Library of Science (PLoS) Article – July 16, 2013

Filed under: Reports and Articles — Tags: — admin @ 4:34 pm

Automated, High Accuracy Classification of Parkinsonian Disorders: A Pattern Recognition Approach,” by Andre F. Marquand, Maurizio Filippone, John Ashburner, Mark Girolami, Janaina Mourao-Miranda, Gareth J. Barker, Steven C. R. Williams, P. Nigel Leigh, and Camilla R. V. Blain ( PLoS ONE 8(7): e69237. doi:10.1371/journal.pone.0069237, XML, HTML, and .pdf format, 10p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069237

June 26, 2013

CAAR – Public Library of Science (PLoS) Articles – June 26, 2013

Filed under: Reports and Articles — Tags: , — admin @ 4:27 pm

A. “Understanding the Relationship between Type 2 Diabetes Mellitus and Falls in Older Adults: A Prospective Cohort Study,” by Tine Roman de Mettelinge, Dirk Cambier, Patrick Calders, Nele Van Den Noortgate, and Kim Delbaere (PLoS ONE 8(6): e67055. doi:10.1371/journal.pone.0067055, XML, HTML, and .pdf format, 5p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0067055

B. “A Functional Magnetic Resonance Imaging Study of Pathophysiological Changes Responsible for Mirror Movements in Parkinson’s Disease,” by Alice Poisson, Benedicte Ballanger, Elise Metereau, Jerome Redoute, Danielle Ibarolla, Jean-Christophe Comte, Helene Gervais Bernard, Marie Vidailhet, Emmanuel Broussolle, and Stephane Thobois (PLoS ONE 8(6): e66910. doi:10.1371/journal.pone.0066910, XML, HTML, and .pdf format, 6p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0066910

C. “Complexity of Motor Sequences and Cortical Reorganization in Parkinson’s Disease: A Functional MRI Study,” by Stefano Caproni, Marco Muti, Massimo Principi, Pierfausto Ottaviano, Domenico Frondizi, Giuseppe Capocchi, Piero Floridi, Aroldo Rossi, Paolo Calabresi, and Nicola Tambasco (PLoS ONE 8(6): e66834. doi:10.1371/journal.pone.0066834, XML, HTML, and .pdf format, 10p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0066834

June 21, 2013

CAAR – Science Report Abstract – June 21, 2013

Filed under: Reports and Articles — Tags: — admin @ 4:12 pm

Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation,” by Jean-Francois Trempe, Veronique Sauve, Karl Grenier, Marjan Seirafi, Matthew Y. Tang, Marie Menade, Sameer Al-Abdul-Wahid, Jonathan Krett, Kathy Wong, Guennadi Kozlov, Bhushan Nagar, Edward A. Fon, and Kalle Gehring (Vol. 340, No. 6139, June 21, 2013, p. 1451-1455).

www.sciencemag.org/content/340/6139/1451.abstract

June 20, 2013

CAAR – Public Library of Science (PLoS) Articles – June 20, 2013

Filed under: Reports and Articles — Tags: , , , — admin @ 4:23 pm

A. “Alcohol Consumption, Types of Alcohol, and Parkinson’s Disease,” by Rui Liu, Xuguang Guo, Yikyung Park, Jian Wang, Xuemei Huang, Albert Hollenbeck, Aaron Blair, and Honglei Chen (PLoS ONE 8(6): e66452. doi:10.1371/journal.pone.0066452, HTML, XML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0066452

B. “Longitudinal Assessment of Amyloid Pathology in Transgenic ArcA{beta} Mice Using Multi-Parametric Magnetic Resonance Imaging,” by Jan Klohs, Igna Wojtyna Politano, Andreas Deistung, Joanes Grandjean, Anna Drewek, Marco Dominietto, Ruth Keist, Ferdinand Schweser, Jurgen R. Reichenbach, Roger M. Nitsch, Irene Knuesel, and Markus Rudin (PLoS ONE 8(6): e66097. doi:10.1371/journal.pone.0066097, XML, HTML, and .pdf format, 12p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0066097

C. “Outcomes of a Geriatric Liaison Intervention to Prevent the Development of Postoperative Delirium in Frail Elderly Cancer Patients: Report on a Multicentre, Randomized, Controlled Trial,” by Liesbeth Hempenius, Joris P. J. Slaets, Dieneke van Asselt, Geertruida H. de Bock, Theo Wiggers, and Barbara L. van Leeuwen (PLoS ONE 8(6): e64834. doi:10.1371/journal.pone.0064834, XML, HTML, and .pdf format, 11p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0064834

May 28, 2013

CAAR – Tables of Contents – May 28, 2013

Filed under: Journal Table of Contents — Tags: , , — admin @ 4:22 pm

Educational Gerontology (Vol. 39, No. 8, August 2013).

www.ingentaconnect.com/content/routledg/uedg/2013/00000039/00000008

Journal of Parkinson’s Disease (Vol. 3, No. 2, 2013).

iospress.metapress.com/content/q0202723np5m/

Rotman International Journal of Pension Management (Vol. 6, No. 1, Spring 2013).

www.rijpm.com/journal/journal_s/39

May 23, 2013

CAAR – Public Library of Science (PLoS) Articles – May 23, 2013

Filed under: Reports and Articles — Tags: , , — admin @ 4:11 pm

A. “Anatomical Correlates of Cognitive Functions in Early Parkinson’s Disease Patients,” by Roberta Biundo, Massimiliano Calabrese, Luca Weis, Silvia Facchini, Gianluigi Ricchieri, Paolo Gallo, and Angelo Antonini (PLoS ONE 8(5): e64222. doi:10.1371/journal.pone.0064222, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0064222

B. “Abnormal Baseline Brain Activity in Non-Depressed Parkinson’s Disease and Depressed Parkinson’s Disease: A Resting-State Functional Magnetic Resonance Imaging Study,” by Xuyun Wen, Xia Wu, Jiangtao Liu, Ke Li, and Li Yao (PLoS ONE 8(5): e63691. doi:10.1371/journal.pone.0063691, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063691

C. “A Longitudinal Study of Cognition, Proton MR Spectroscopy and Synaptic and Neuronal Pathology in Aging Wild-type and A{beta}PPswe-PS1dE9 Mice,” by Diane Jansen, Valerio Zerbi, Carola I. F. Janssen, Pieter J. W. C. Dederen, Martina P. C. Mutsaers, Anne Hafkemeijer, Anna-Lena Janssen, Cindy L. M. Nobelen, Andor Veltien, Jack J. Asten, Arend Heerschap, and Amanda J. Kiliaan (PLoS ONE 8(5): e63643. doi:10.1371/journal.pone.0063643, XML, HTML, and .pdf format, 17p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063643

D. “Association between Dopamine D4 Receptor Polymorphism and Age Related Changes in Brain Glucose Metabolism,” by Nora D. Volkow, Dardo Tomasi, Gene-Jack Wang, Frank Telang, Joanna S. Fowler, Rita Z. Goldstein, Nelly Klein, Christopher Wong, James M. Swanson, and Elena Shumay (PLoS ONE 8(5): e63492. doi:10.1371/journal.pone.0063492, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063492

May 21, 2013

CAAR – Proceedings of the National Academy of Sciences Article Abstract – May 21, 2013

Filed under: Reports and Articles — Tags: — admin @ 4:32 pm

Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan,” by Anil Rana, Michael Rera, and David W. Walker (Vol. 110, No. 21, May 21, 2013, p. 8638-8643).

www.pnas.org/content/110/21/8638.abstract.html?etoc

May 16, 2013

CAAR – Public Library of Science (PLoS) Articles – May 16, 2013

Filed under: Reports and Articles — Tags: , , , — admin @ 4:31 pm

A. “Diagnostic Value of the Impairment of Olfaction in Parkinson’s Disease,” by Swaantje Casjens, Angelika Eckert, Dirk Woitalla, Gisa Ellrichmann, Michael Turewicz, Christian Stephan, Martin Eisenacher, Caroline May, Helmut E. Meyer, Thomas Bruning, and Beate Pesch (PLoS ONE 8(5): e64735. doi:10.1371/journal.pone.0064735, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0064735

B. “Movement Disorders in Elderly Users of Risperidone and First Generation Antipsychotic Agents: A Canadian Population-Based Study,” by Irina Vasilyeva, Robert G. Biscontri, Murray W. Enns, Colleen J. Metge, and Silvia Alessi-Severini (PLoS ONE 8(5): e64217. doi:10.1371/journal.pone.0064217, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0064217

C. “Intravenous Immunglobulin Binds Beta Amyloid and Modifies Its Aggregation, Neurotoxicity and Microglial Phagocytosis In Vitro,” by Susann Cattepoel, Alexander Schaub, Miriam Ender, Annette Gaida, Alain Kropf, Ursula Guggisberg, Marc W. Nolte, Louis Fabri, Paul A. Adlard, David I. Finkelstein, Reinhard Bolli, and Sylvia M. Miescher (PLoS ONE 8(5): e63162. doi:10.1371/journal.pone.0063162, XML, HTML, and .pdf format, 14p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063162

May 9, 2013

CAAR – Public Library of Science (PLoS) Articles – May 9, 2013

Filed under: Reports and Articles — Tags: , , — admin @ 4:13 pm

A. “Effect of Hormone Replacement Therapy on Cardiovascular Outcomes: A Meta-Analysis of Randomized Controlled Trials,” by Dicheng Yang, Jing Li, Zhongxiang Yuan, and Xu Liu (PLoS ONE 8(5): e62329. doi:10.1371/journal.pone.0062329, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062329

B. “Colour Constancy Across the Life Span: Evidence for Compensatory Mechanisms,” by Sophie Wuerger (PLoS ONE 8(5): e63921. doi:10.1371/journal.pone.0063921, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063921

C. “Could Sensory Mechanisms Be a Core Factor That Underlies Freezing of Gait in Parkinson’s Disease?” by Kaylena A. Ehgoetz Martens, Frederico Pieruccini-Faria, and Quincy J. Almeida (PLoS ONE 8(5): e62602. doi:10.1371/journal.pone.0062602, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062602

May 8, 2013

CAAR – Public Library of Science (PLoS) Articles – May 8, 2013

Filed under: Reports and Articles — Tags: , , , — admin @ 4:42 pm

A. “Metabolic States Following Accumulation of Intracellular Aggregates: Implications for Neurodegenerative Diseases,” by Alexei Vazquez (PLoS ONE 8(5): e63822. doi:10.1371/journal.pone.0063822, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063822

B. “The Relationship between P3 Amplitude and Working Memory Performance Differs in Young and Older Adults,” by Emi Saliasi, Linda Geerligs, Monicque M. Lorist, and Natasha M. Maurits (PLoS ONE 8(5): e63701. doi:10.1371/journal.pone.0063701, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063701

C. “Impairment of Mitochondria in Adult Mouse Brain Overexpressing Predominantly Full-Length, N-Terminally Acetylated Human {alpha}-Synuclein,” by Theodore A. Sarafian, Christopher M. Ryan, Puneet Souda, Eliezer Masliah, Upendra K. Kar, Harry V. Vinters, Gary W. Mathern, Kym F. Faull, Julian P. Whitelegge, and Joseph B. Watson (PLoS ONE 8(5): e63557. doi:10.1371/journal.pone.0063557, XML, HTML, and .pdf format, 15p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063557

D. “Cerebrospinal Fluid Melanin-Concentrating Hormone (MCH) and Hypocretin-1 (HCRT-1, Orexin-A) in Alzheimer’s Disease,” by Frank M. Schmidt, Juergen Kratzsch, Hermann-Josef Gertz, Mandy Tittmann, Ina Jahn, Uta-Carolin Pietsch, Udo X. Kaisers, Joachim Thiery, Ulrich Hegerl, and Peter Schonknecht (PLoS ONE 8(5): e63136. doi:10.1371/journal.pone.0063136, XML, HTML, and .pdf format, 6p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063136

E. “Rapamycin Attenuates the Progression of Tau Pathology in P301S Tau Transgenic Mice,” by Sefika Ozcelik, Graham Fraser, Perrine Castets, Veronique Schaeffer, Zhiva Skachokova, Karin Breu, Florence Clavaguera, Michael Sinnreich, Ludwig Kappos, Michel Goedert, Markus Tolnay, and David Theo Winkler (PLoS ONE 8(5): e62459. doi:10.1371/journal.pone.0062459, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062459

April 24, 2013

CAAR – Public Library of Science (PLoS) Articles – April 24, 2013

Filed under: Reports and Articles — Tags: , , — admin @ 4:15 pm

A. “FDG PET and MRI in Logopenic Primary Progressive Aphasia versus Dementia of the Alzheimer’s Type,” by Ajay Madhavan, Jennifer L. Whitwell, Stephen D. Weigand, Joseph R. Duffy, Edythe A. Strand, Mary M. Machulda, Nirubol Tosakulwong, Matthew L. Senjem, Jeffrey L. Gunter, Val J. Lowe, Ronald C. Petersen, Clifford R. Jack, and Keith A. Josephs (PLoS ONE 8(4): e62471. doi:10.1371/journal.pone.0062471, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062471

B. “TOM40 Mediates Mitochondrial Dysfunction Induced by {alpha}-Synuclein Accumulation in Parkinson’s Disease,” by Andreas Bender, Paula Desplats, Brian Spencer, Edward Rockenstein, Anthony Adame, Matthias Elstner, Christoph Laub, Sarina Mueller, Andrew O. Koob, Michael Mante, Emily Pham, Thomas Klopstock, and Eliezer Masliah (PLoS ONE 8(4): e62277. doi:10.1371/journal.pone.0062277, XML, HTML, and .pdf format, 11p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062277

C. “Calcitriol Imparts Neuroprotection In Vitro to Midbrain Dopaminergic Neurons by Upregulating GDNF Expression,” by Rowan P. Orme, Manminder S. Bhangal, and Rosemary A. Fricker (PLoS ONE 8(4): e62040. doi:10.1371/journal.pone.0062040, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062040

D. “Population-Based 5-Year Follow-Up Study in Taiwan of Dementia and Risk of Stroke,” by Mu-En Liu, Shih-Jen Tsai, Wei-Chiao Chang, Chun-Hung Hsu, Ti Lu, Kuo-Sheng Hung, Wen-Ta Chiu, and Wei-Pin Chang (PLoS ONE 8(4): e61771. doi:10.1371/journal.pone.0061771, XML, HTML, and .pdf format, 6p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0061771

April 19, 2013

CAAR – Public Library of Science (PLoS) Articles – April 19, 2013

A. “Bee Venom and Its Component Apamin as Neuroprotective Agents in a Parkinson Disease Mouse Model,” by Daniel Alvarez-Fischer, Carmen Noelker, Franca Vulinovic, Anne Grunewald, Caroline Chevarin, Christine Klein, Wolfgang H. Oertel, Etienne C. Hirsch, Patrick P. Michel, and Andreas Hartmann (PLoS ONE 8(4): e61700. doi:10.1371/journal.pone.0061700, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0061700

B. “Social Participation and Dental Health Status among Older Japanese Adults: A Population-Based Cross-Sectional Study,” by Kenji Takeuchi, Jun Aida, Katsunori Kondo, and Ken Osaka (PLoS ONE 8(4): e61741. doi:10.1371/journal.pone.0061741, XML, HTML, and .pdf format, 6p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0061741

C. “Olfactory Training in Patients with Parkinson’s Disease,” by Antje Haehner, Clara Tosch, Martin Wolz, Lisa Klingelhoefer, Mareike Fauser, Alexander Storch, Heinz Reichmann, and Thomas Hummel (PLoS ONE 8(4): e61680. doi:10.1371/journal.pone.0061680, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0061680

D. “Minocycline Attenuates Cognitive Impairment Induced by Isoflurane Anesthesia in Aged Rats,” by Feijuan Kong, Shuping Chen, Yuan Cheng, Leilei Ma, Huishun Lu, Honghai Zhang, and Wenwen Hu (PLoS ONE 8(4): e61385. doi:10.1371/journal.pone.0061385, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0061385

E. “Mild Oxidative Stress Induces Redistribution of BACE1 in Non-Apoptotic Conditions and Promotes the Amyloidogenic Processing of Alzheimer’s Disease Amyloid Precursor Protein,” by Jiang-Li Tan, Qiao-Xin Li, Giuseppe D. Ciccotosto, Peter John Crouch, Janetta Gladys Culvenor, Anthony Robert White, and Genevieve Evin (PLoS ONE 8(4): e61246. doi:10.1371/journal.pone.0061246, XML, HTML, and .pdf format, 14p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0061246

April 17, 2013

CAAR – Nature Letter Abstract – April 17, 2013

Filed under: Reports and Articles — Tags: — admin @ 4:37 pm

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization,” by Shireen A. Sarraf, Malavika Raman, Virginia Guarani-Pereira, Mathew E. Sowa, Edward L. Huttlin, Steven P. Gygi & J. Wade Harper (Vol. 496, No. 745, April 17, 2013, p. 372-376).

www.nature.com/nature/journal/v496/n7445/abs/nature12043.html

April 3, 2013

CAAR – Public Library of Science (PLoS) Articles – April 3, 2013

A. “Hunger in the Absence of Caloric Restriction Improves Cognition and Attenuates Alzheimer’s Disease Pathology in a Mouse Model,” by Emily J. Dhurandhar, David B. Allison, Thomas van Groen, and Inga Kadish (PLoS ONE 8(4): e60437. doi:10.1371/journal.pone.0060437, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0060437

B. “SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians,” by Akinori Miyashita, Asako Koike, Gyungah Jun, Li-San Wang, Satoshi Takahashi, Etsuro Matsubara, Takeshi Kawarabayashi, Mikio Shoji, Naoki Tomita, Hiroyuki Arai, Takashi Asada, Yasuo Harigaya, Masaki Ikeda, Masakuni Amari, Haruo Hanyu, Susumu Higuchi, Takeshi Ikeuchi, Masatoyo Nishizawa, Masaichi Suga, Yasuhiro Kawase, Hiroyasu Akatsu, Kenji Kosaka, Takayuki Yamamoto, Masaki Imagawa, Tsuyoshi Hamaguchi, Masahito Yamada, Takashi Moriaha, Masatoshi Takeda, Takeo Takao, Kenji Nakata, Yoshikatsu Fujisawa, Ken Sasaki, Ken Watanabe, Kenji Nakashima, Katsuya Urakami, Terumi Ooya, Mitsuo Takahashi, Takefumi Yuzuriha, Kayoko Serikawa, Seishi Yoshimoto, Ryuji Nakagawa, Jong-Won Kim, Chang-Seok Ki, Hong-Hee Won, Duk L. Na, Sang Won Seo, Inhee Mook-Jung, The Alzheimer Disease Genetics Consortium, Peter St. George-Hyslop, Richard Mayeux, Jonathan L. Haines, Margaret A. Pericak-Vance, Makiko Yoshida, Nao Nishida, Katsushi Tokunaga, Ken Yamamoto, Shoji Tsuji, Ichiro Kanazawa, Yasuo Ihara, Gerard D. Schellenberg, Lindsay A. Farrer, and Ryozo Kuwano (PLoS ONE 8(4): e58618. doi:10.1371/journal.pone.0058618, XML, HTML, and .pdf format, 11p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058618

C. “Age-Dependent Effects of A53T Alpha-Synuclein on Behavior and Dopaminergic Function,” by Adam W. Oaks, Maya Frankfurt, David I. Finkelstein, and Anita Sidhu (PLoS ONE 8(4): e60378. doi:10.1371/journal.pone.0060378, XML, HTML, and .pdf format, 15p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0060378

D. “Neuroinflammation and Neuronal Loss Precede A{beta} Plaque Deposition in the hAPP-J20 Mouse Model of Alzheimer’s Disease,” by Amanda L. Wright, Raphael Zinn, Barbara Hohensinn, Lyndsey M. Konen, Sarah B. Beynon, Richard P. Tan, Ian A. Clark, Andrea Abdipranoto, and Bryce Vissel (PLoS ONE 8(4): e59586. doi:10.1371/journal.pone.0059586, XML, HTML, and .pdf format, 14p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059586

E. “Time’s Up. Descriptive Epidemiology of Multi-Morbidity and Time Spent on Health Related Activity by Older Australians: A Time Use Survey,” by Tanisha Jowsey, Ian S. McRae, Jose M. Valderas, Paul Dugdale, Rebecca Phillips, Robin Bunton, James Gillespie, Michelle Banfield, Lesley Jones, Marjan Kljakovic, and Laurann Yen (PLoS ONE 8(4): e59379. doi:10.1371/journal.pone.0059379, XML, HTML, and .pdf format, 6p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059379

April 2, 2013

CAAR – Tables of Contents – April 2, 2013

Filed under: Journal Table of Contents — Tags: , — admin @ 4:44 pm

Journal of Parkinson’s Disease (Vol. 3, No. 1, 2013).

iospress.metapress.com/content/x7246m80h058/

Research on Aging (Vol. 35, No. 3, May 2013).

roa.sagepub.com/content/35/3.toc

March 26, 2013

CAAR – Public Library of Science (PLoS) Articles – March 26, 2013

A. “Waist Circumference, Not Body Mass Index, Is Associated with Renal Function Decline in Korean Population: Hallym Aging Study,” by Hyunju Oh, Shan Ai Quan, Jin-Young Jeong, Soong-Nang Jang, Jung Eun Lee, and Dong-Hyun Kim (PLoS ONE 8(3): e59071. doi:10.1371/journal.pone.0059071, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059071

B. “Mortality Risk amongst Nursing Home Residents Evacuated after the Fukushima Nuclear Accident: A Retrospective Cohort Study,” by Shuhei Nomura, Stuart Gilmour, Masaharu Tsubokura, Daisuke Yoneoka, Amina Sugimoto, Tomoyoshi Oikawa, Masahiro Kami, and Kenji Shibuya (PLoS ONE 8(3): e60192. doi:10.1371/journal.pone.0060192, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0060192

C. “Ovariectomy Induces a Shift in Fuel Availability and Metabolism in the Hippocampus of the Female Transgenic Model of Familial Alzheimer’s,” by Fan Ding, Jia Yao, Liqin Zhao, Zisu Mao, Shuhua Chen, and Roberta Diaz Brinton (PLoS ONE 8(3): e59825. doi:10.1371/journal.pone.0059825, XML, HTML, and .pdf format, 11p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059825

D. “Characterization of a Single-Chain Variable Fragment Recognizing a Linear Epitope of A{beta}: A Biotechnical Tool for Studies on Alzheimer’s Disease?” by Silke Dornieden, Andreas Müller-Schiffmann, Heinrich Sticht, Nan Jiang, Yeliz Cinar, Michael Wordehoff, Carsten Korth, Susanne Aileen Funke, and Dieter Willbold (PLoS ONE 8(3): e59820. doi:10.1371/journal.pone.0059820, XML, HTML, and .pdf format, 11p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059820

E. “Enhanced Functional Connectivity between Putamen and Supplementary Motor Area in Parkinson’s Disease Patients,” by Rongjun Yu, Bo Liu, Lingling Wang, Jun Chen, and Xian Liu (PLoS ONE 8(3): e59717. doi:10.1371/journal.pone.0059717, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059717

CAAR – Nature Neuroscience Article Abstracts – March 26, 2013

Filed under: Reports and Articles — Tags: , , — admin @ 4:56 pm

A. “Interplay of LRRK2 with chaperone-mediated autophagy,” by Samantha J. Orenstein, Sheng-Han Kuo, Inmaculada Tasset, Esperanza Arias, Hiroshi Koga, Irene Fernandez-Carasa, Etty Cortes, Lawrence S Honig, William Dauer, Antonella Consiglio, Angel Raya, David Sulzer and Ana Maria Cuervo (Vol. 16, No. 4, April 2013, p. 394-406).

www.nature.com/neuro/journal/v16/n4/abs/nn.3350.html

B. “Low hippocampal PI(4,5)P2 contributes to reduced cognition in old mice as a result of loss of MARCKS,” by Laura Trovo, Tariq Ahmed, Zsuzsanna Callaerts-Vegh, Andrea Buzzi, Claudia Bagni, Marinee Chuah, Thierry VandenDriessche, Rudi D’Hooge, Detlef Balschun and Carlos G. Dotti (Vol. 16, No. 4, April 2013, p. 449-455).

www.nature.com/neuro/journal/v16/n4/abs/nn.3342.html

March 19, 2013

CAAR – Proceedings of the National Academy of Sciences Article Abstracts – March 19, 2013

Filed under: Reports and Articles — Tags: , — admin @ 4:06 pm

A. “Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity,” by Neda Jahanshad, Priya Rajagopalan, Xue Hua, Derrek P. Hibar, Talia M. Nir, Arthur W. Toga, Clifford R. Jack, Jr, Andrew J. Saykin, Robert C. Green, Michael W. Weiner, Sarah E. Medland, Grant W. Montgomery, Narelle K. Hansell, Katie L. McMahon, Greig I. de Zubicaray, Nicholas G. Martin, Margaret J. Wright, Paul M. Thompson, and the Alzheimer’s Disease Neuroimaging Initiative (Vol. 110, No. 12, March 19, 2013, .pdf and HTML format, p. 4768-4773). Note: PNAS is providing open access to the full-text of this article.

www.pnas.org/content/110/12/4768.abstract.html?etoc

B. “Exaggerated phase-amplitude coupling in the primary motor cortex in Parkinson disease,” by Coralie de Hemptinne, Elena S. Ryapolova-Webb, Ellen L. Air, Paul A. Garcia, Kai J. Miller, Jeffrey G. Ojemann, Jill L. Ostrem, Nicholas B. Galifianakis, and Philip A. Starr (Vol. 110, No. 12, March 19, 2013, p. 4780-4785).

www.pnas.org/content/110/12/4780.abstract.html?etoc

March 18, 2013

CAAR – Lancet Neurology Article Abstracts – March 18, 2013

Filed under: Reports and Articles — Tags: , — admin @ 3:46 pm

Note: Lancet requires free registration prior to providing content.

A. “Amyloid {beta} deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer’s disease: a prospective cohort study,” by Victor L. Villemagne, Samantha Burnham, Pierrick Bourgeat, Belinda Brown, Kathryn A. Ellis, Olivier Salvado, Cassandra Szoeke, S. Lance Macaulay, Ralph Martins, Paul Maruff, David Ames, Christopher C. Rowe, and Colin L. Masters, for the Australian Imaging Biomarkers and Lifestyle (AIBL) Research Group (Vol. 12, No. 4, April 4, p. 357-367).

www.thelancet.com/journals/laneur/article/PIIS1474-4422%2813%2970044-9/abstract

B. “Extended-release carbidopa-levodopa (IPX066) compared with immediate-release carbidopa-levodopa in patients with Parkinson’s disease and motor fluctuations: a phase 3 randomised, double-blind trial,” by Robert A. Hauser, Ann Hsu, Sherron Kell, Alberto J. Espay, Kapil Sethi, Mark Stacy, William Ondo, Martin O’Connell, and Suneel Gupta, for the IPX066 ADVANCE-PD investigators (Vol. 12, No. 4, April 4, p. 346-356).

www.thelancet.com/journals/laneur/article/PIIS1474-4422%2813%2970025-5/abstract

March 12, 2013

CAAR – Public Library of Science (PLoS) Articles – March 12, 2013

A. “Subclinical Thyroid Dysfunction and Cognitive Decline in Old Age,” by Liselotte W. Wijsman, Anton J. M. de Craen, Stella Trompet, Jacobijn Gussekloo, David J. Stott, Nicolas Rodondi, Paul Welsh, J. Wouter Jukema, Rudi G. J. Westendorp, and Simon P. Mooijaart (PLoS ONE 8(3): e59199. doi:10.1371/journal.pone.0059199, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059199

B. “PINCH in the Cellular Stress Response to Tau-Hyperphosphorylation,” by Ahmet Yunus Ozdemir, Inna Rom, Jane Kovalevich, William Yen, Radhika Adiga, Rajnish S. Dave, and Dianne Langford (PLoS ONE 8(3): e58232. doi:10.1371/journal.pone.0058232, XML, HTML, and .pdf format, 11p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058232

C. “Single-Subject Grey Matter Graphs in Alzheimer’s Disease,” by Betty M. Tijms, Christiane Moller, Hugo Vrenken, Alle Meije Wink, Willem de Haan, Wiesje M. van der Flier, Cornelis J. Stam, Philip Scheltens, and Frederik Barkhof (PLoS ONE 8(3): e58921. doi:10.1371/journal.pone.0058921, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058921

D. “United States Acculturation and Cancer Patients’ End-of-Life Care,” by Alexi A. Wright, Heather Stieglitz, Yankel M. Kupersztoch, M. Elizabeth Paulk, Yookyung Kim, Ingrid T. Katz, Francisco Munoz, Rachel B. Jimenez, Jan Mutchler, Lorna Rivera, Anthony L. Back, and Holly G. Prigerson (PLoS ONE 8(3): e58663. doi:10.1371/journal.pone.0058663, XML, HTML, and .pdf format, 10p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058663

E. “Force Control Deficits in Individuals with Parkinson’s Disease, Multiple Systems Atrophy, and Progressive Supranuclear,” by Palsy Kristina A. Neely, Peggy J. Planetta, Janey Prodoehl, Daniel M. Corcos, Cynthia L. Comella, Christopher G. Goetz, Kathleen L. Shannon, and David E. Vaillancourt (PLoS ONE 8(3): e58403. doi:10.1371/journal.pone.0058403, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0058403

March 8, 2013

CAAR – British Medical Journal Articles – March 8, 2013

Filed under: Reports and Articles — Tags: , — admin @ 4:54 pm

A. “Promotion of physical activity and fitness in sedentary patients with Parkinson’s disease: randomised controlled trial,” by Marlies van Nimwegen, Arlene D. Speelman, Sebastiaan Overeem, Bart P. van de Warrenburg, Katrijn Smulders, Manon L. Dontje, George F. Borm, Frank J. G. Backx, Bastiaan R. Bloem, and Marten Munneke, on behalf of the ParkFit Study Group (Vol. 346, No. 7898, BMJ 2013;346:f576, .pdf and HTML format).

www.bmj.com/content/346/bmj.f576

B. “Income inequality and 30 day outcomes after acute myocardial infarction, heart failure, and pneumonia: retrospective cohort study,” by Peter K. Lindenauer, Tara Lagu, Michael B. Rothberg, Jill Avrunin, Penelope S. Pekow, Yongfei Wang, and Harlan M. Krumholz (Vol. 346, No. 7898, BMJ 2013;346:f521, .pdf and HTML format).

www.bmj.com/content/346/bmj.f521

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