CDHA CAAR » neurodegeneration http://www.ssc.wisc.edu/cdha/cinfo Current Awareness in Aging Research Thu, 02 May 2013 21:40:03 +0000 en hourly 1 http://wordpress.org/?v=3.1.4 CAAR – Nature Neuroscience Article, Brief Communication Abstracts- April 25, 2013 http://www.ssc.wisc.edu/cdha/cinfo/?p=4996 http://www.ssc.wisc.edu/cdha/cinfo/?p=4996#comments Thu, 25 Apr 2013 21:11:16 +0000 admin http://www.ssc.wisc.edu/cdha/cinfo/?p=4996 A. “Spike bursts increase amyloid-{beta} 40/42 ratio by inducing a presenilin-1 conformational change,” by Iftach Dolev, Hilla Fogel, Hila Milshtein, Yevgeny Berdichevsky, Noa Lipstein, Nils Brose, Neta Gazit & Inna Slutsky (Vol. 16, No. 5, May 2013, p. 587-595).

www.nature.com/neuro/journal/v16/n5/abs/nn.3376.html

B. “Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-{beta},” by Elsa Suberbielle, Pascal E Sanchez, Alexxai V Kravitz, Xin Wang, Kaitlyn Ho, Kirsten Eilertson, Nino Devidze, Anatol C Kreitzer and Lennart Mucke (Vol. 16, No. 5, May 2013, p. 613-619).

www.nature.com/neuro/journal/v16/n5/abs/nn.3356.html

C. “Dopamine restores reward prediction errors in old age,” by Rumana Chowdhury, Marc Guitart-Masip, Christian Lambert, Peter Dayan, Quentin Huys, Emrah Düzel & Raymond J Dolan (Vol. 16, No. 5, May 2013, p. 648-653).

www.nature.com/neuro/journal/v16/n5/abs/nn.3364.html

D. “Activation of transposable elements during aging and neuronal decline in Drosophila,” by Wanhe Li, Lisa Prazak, Nabanita Chatterjee, Servan Gruninger, Lisa Krug, Delphine Theodorou & Josh Dubnau (Vol. 16, No. 5, May 2013, p. 529-531).

www.nature.com/neuro/journal/v16/n5/abs/nn.3368.html

]]> http://www.ssc.wisc.edu/cdha/cinfo/?feed=rss2&p=4996 0 CAAR – Public Library of Science (PLoS) Article – April 23, 2013 http://www.ssc.wisc.edu/cdha/cinfo/?p=4972 http://www.ssc.wisc.edu/cdha/cinfo/?p=4972#comments Tue, 23 Apr 2013 21:53:09 +0000 admin http://www.ssc.wisc.edu/cdha/cinfo/?p=4972 “Molecular Ageing of Alpha- and Beta-Synucleins: Protein Damage and Repair Mechanisms,” by Vasanthy Vigneswara, Simon Cass, Declan Wayne, Edward L. Bolt, David E. Ray, and Wayne G. Carter (PLoS ONE 8(4): e61442. doi:10.1371/journal.pone.0061442, XML, HTML, and .pdf format, 12p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0061442

]]> http://www.ssc.wisc.edu/cdha/cinfo/?feed=rss2&p=4972 0 CAAR – Lancet Neurology Article Abstract – April 19, 2013 http://www.ssc.wisc.edu/cdha/cinfo/?p=4934 http://www.ssc.wisc.edu/cdha/cinfo/?p=4934#comments Fri, 19 Apr 2013 21:40:03 +0000 admin http://www.ssc.wisc.edu/cdha/cinfo/?p=4934 “Neurodegenerative disease status and post-mortem pathology in idiopathic rapid-eye-movement sleep behaviour disorder: an observational cohort study,” by Dr. Alex Iranzo, Prof. Eduard Tolosa, Ellen Gelpi, Jose Luis Molinuevo, Francesc Valldeoriola, Monica Serradell, Raquel Sanchez-Valle, Isabel Vilaseca, Francisco Lomena, Dolores Vilas, Albert LLado, Carles Gaig, and Joan Santamaria (Vol. 12, No. 4, April 2013, p. 443-453).

www.thelancet.com/journals/laneur/article/PIIS1474-4422(13)70056-5/abstract

]]> http://www.ssc.wisc.edu/cdha/cinfo/?feed=rss2&p=4934 0 CAAR – Public Library of Science (PLoS) Articles – July 26, 2012 http://www.ssc.wisc.edu/cdha/cinfo/?p=2325 http://www.ssc.wisc.edu/cdha/cinfo/?p=2325#comments Thu, 26 Jul 2012 20:53:49 +0000 admin http://www.ssc.wisc.edu/cdha/cinfo/?p=2325 A. “Establishment of Induced Pluripotent Stem Cells from Centenarians for Neurodegenerative Disease Research,” by Takuya Yagi, Arifumi Kosakai, Daisuke Ito, Wado Akamatsu, Yoshihiro Nihei, Akira Nabetani, Fuyuki Ishikawa, Yasumichi Arai, Nobuyoshi Hirose, Hideyuki Okano, and Norihiro Suzuki (PLoS ONE 7(7): e41572. doi:10.1371/journal.pone.0041572, XML, HTML, and .pdf format, 7p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0041572

B. “Disruption of Arterial Perivascular Drainage of Amyloid-{beta} from the Brains of Mice Expressing the Human APOE e4 Allele,” by Cheryl A. Hawkes, Patrick M. Sullivan, Sarah Hands, Roy O. Weller, James A. R. Nicoll, and Roxana O. Carare (PLoS ONE 7(7): e41636. doi:10.1371/journal.pone.0041636, XML, HTML, and .pdf format, 11p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0041636

]]> http://www.ssc.wisc.edu/cdha/cinfo/?feed=rss2&p=2325 0 CAAR – Public Library of Science (PLoS) Articles – July 5, 2012 http://www.ssc.wisc.edu/cdha/cinfo/?p=2077 http://www.ssc.wisc.edu/cdha/cinfo/?p=2077#comments Thu, 05 Jul 2012 20:37:15 +0000 admin http://www.ssc.wisc.edu/cdha/cinfo/?p=2077 A. “25-Hydroxyvitamin D Depletion Does Not Exacerbate MPTP-Induced Dopamine Neuron Damage in Mice,” by E. Danielle Dean, Lydia M. Mexas, Natalie L. Capiro, Jeanne E. McKeon, Mahlon R. DeLong, Kurt D. Pennell, Jonathan A. Doorn, Vin Tangpricha, Gary W. Miller, and Marian L. Evatt (PLoS ONE 7(7): e39227. doi:10.1371/journal.pone.0039227, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0039227

B. “Plasma BDNF Levels Vary in Relation to Body Weight in Females,” by Anilkumar Pillai, Davide Bruno, Antero S. Sarreal, Raymundo T. Hernando, Leslie A. Saint-Louis, Jay Nierenberg, Stephen D. Ginsberg, Nunzio Pomara, Pankaj D. Mehta, Henrik Zetterberg, Kaj Blennow, and Peter F. Buckley (PLoS ONE 7(7): e39358. doi:10.1371/journal.pone.0039358, XML, HTML, and .pdf format, 6p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0039358

C. “Executive Function and Falls in Older Adults: New Findings from a Five-Year Prospective Study Link Fall Risk to Cognition,” by Anat Mirelman, Talia Herman, Marina Brozgol, Moran Dorfman, Elliot Sprecher, Avraham Schweiger, Nir Giladi, and Jeffrey M. Hausdorff (PLoS ONE 7(6): e40297. doi:10.1371/journal.pone.0040297, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0040297

D. “Sexual Dimorphism in Healthy Aging and Mild Cognitive Impairment: A DTI Study,” by Laurence O’Dwyer, Franck Lamberton, Arun L. W. Bokde, Michael Ewers, Yetunde O. Faluyi, Colby Tanner, Bernard Mazoyer, Desmond O’Neill, Mairead Bartley, Ronan Collins, Tara Coughlan, David Prvulovic, and Harald Hampel (PLoS ONE 7(7): e37021. doi:10.1371/journal.pone.0037021, XML, HTML, and .pdf format, 12p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0037021

]]> http://www.ssc.wisc.edu/cdha/cinfo/?feed=rss2&p=2077 0 CAAR – Nature Letter Abstracts – May 23, 2012 http://www.ssc.wisc.edu/cdha/cinfo/?p=1660 http://www.ssc.wisc.edu/cdha/cinfo/?p=1660#comments Wed, 23 May 2012 20:30:53 +0000 admin http://www.ssc.wisc.edu/cdha/cinfo/?p=1660 A. “Apolipoprotein E controls cerebrovascular integrity via cyclophilin A,” by Robert D. Bell, Ethan A. Winkler, Itender Singh, Abhay P. Sagare, Rashid Deane, Zhenhua Wu, David M. Holtzman, Christer Betsholtz, Annika Armulik, Jan Sallstrom, Bradford C. Berk, & Berislav V. Zlokovic (Vol. 485, No. 7399, May 24, 2012, p. 512-516).

www.nature.com/nature/journal/v485/n7399/abs/nature11087.html

B. “Sustained translational repression by eIF2a-P mediates prion neurodegeneration,” by Julie A. Moreno, Helois Radford, Diego Peretti, Joern R. Steinert, Nicholas Verity, Maria Guerra Martin, Mark Halliday, Jason Morgan, David Dinsdale, Catherine A. Ortori, David A. Barrett, Pavel Tsaytler, Anne Bertolotti, Anne E. Willis, Martin Bushell, & Giovanna R. Mallucci (Vol. 485, No. 7399, May 24, 2012, p. 507-511).

www.nature.com/nature/journal/v485/n7399/abs/nature11058.html

]]> http://www.ssc.wisc.edu/cdha/cinfo/?feed=rss2&p=1660 0 CAAR – Proceedings of the National Academy of Sciences Article – March 14, 2012 http://www.ssc.wisc.edu/cdha/cinfo/?p=870 http://www.ssc.wisc.edu/cdha/cinfo/?p=870#comments Wed, 14 Mar 2012 20:33:44 +0000 admin http://www.ssc.wisc.edu/cdha/cinfo/?p=870 Proceedings of the National Academy of Sciences Article Abstracts:

A. “Telomere maintenance and telomerase activity are differentially regulated in asexual and sexual worms,” by Thomas C.J. Tan, Ruman Rahman, Farah Jaber-Hijazi, Daniel A. Felix, Chen Chen, Edward J. Louis, and Aziz Aboobaker (Vol. 109, No. 11, Mar. 13, 2012, HTML and .pdf format, p. 4209-4214). This article is available free of charge.

www.pnas.org/content/109/11/4209.full

B. ”ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila,” by Andrew J. Petersen, Stacey A. Rimkus, and David A. Wassarman (Vol. 109, No. 11, March 14, 2012, p. E656-E664).

www.pnas.org/content/109/11/E656.abstract

]]> http://www.ssc.wisc.edu/cdha/cinfo/?feed=rss2&p=870 0 CAAR – Public Library of Science (PLoS) Articles – February 9, 2012 http://www.ssc.wisc.edu/cdha/cinfo/?p=461 http://www.ssc.wisc.edu/cdha/cinfo/?p=461#comments Thu, 09 Feb 2012 21:26:41 +0000 admin http://www.ssc.wisc.edu/cdha/cinfo/?p=461 A. “Creatine Protects against Excitoxicity in an In Vitro Model of Neurodegeneration,” by Just Genius, Johanna Geiger, Andreas Bender, Hans-Jurgen Moller, Thomas Klopstock, and Dan Rujescu (PLoS ONE 7(2): e30554. doi:10.1371/journal.pone.0030554, XML, HTML, and .pdf format, 8p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0030554

B. “Massage Therapy for Osteoarthritis of the Knee: A Randomized Dose-Finding Trial,” by Adam I. Perlman, Ather Ali, Valentine Yanchou Njike, David Hom, Anna Davidi, Susan Gould-Fogerite, Carl Milak, and David L. Katz (PLoS ONE 7(2): e30248. doi:10.1371/journal.pone.0030248, XML, HTML, and .pdf format, 9p.).

www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0030248

]]> http://www.ssc.wisc.edu/cdha/cinfo/?feed=rss2&p=461 0